Results 81 to 90 of about 211,053 (311)

Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction. [PDF]

, 2016
BACKGROUND: Postoperative cognitive dysfunction (POCD) is a common complication after surgery, especially amongst elderly patients. Neuroinflammation and iron homeostasis are key hallmarks of several neurological disorders. In this study, we investigated
Guocai Tao, Ke Pan, Jiao-lin Ning, Tao, Guocai, Lin Chen (54305), Yuping Li, Niccolò Terrando, Ting Yang, Li, Yuping, Lin Chen, Xiaojun Li, Chen, Lin, Jiao-lin Ning (3451655), Guocai Tao (3451661), Jianteng Gu (3451658), Jianteng Gu, Ning, Jiao-Lin, Pan, Ke, Xiaojun Li (138162), Terrando, Niccolò, Ke Pan (200562), Yuping Li (157863), Li, Xiaojun, Yang, Ting, Gu, Jianteng   +24 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Advances in Neuroinflammation

Brain Sciences
Recent research in neuroscience has shown significant advancements in relation to neuroinflammation, especially its role in neurological diseases, including neurodegenerative diseases [...]
Junhui Wang, Jing Sun, Hongxing Wang
openaire   +3 more sources

Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFκB pathway following asphyxial cardiac arrest in rats

, 2020
Background: Cardiac arrest survivors suffer from neurological dysfunction including cognitive impairment. Cerebral mast cells, the key regulators of neuroinflammation contribute to neuroinflammation-associated cognitive dysfunction.
Xu, Weilin, Zhang, Guangyu, Huang, Lei, Gamdzyk, Marcin, Ocak, Umut, Mo, Jun, Li, Peng, Zhang, John H, Zuo, Gang, Zuo, Yuchun   +9 more
core   +1 more source

4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis

, 2021
Background: Multiple sclerosis (MS) is a progressive autoimmune disease characterized by the accumulation of pathogenic inflammatory immune cells in the central nervous system (CNS) that subsequently causes focal inflammation, demyelination, axonal ...
Brown, Dennis A., Wang, Pei-Yu, Paraiso, Hallel C., Yu, I-Chen, Yen, Jui-Hung, Kuo, Ping-Chang, Scofield, Barbara A., Furnas, Destin, Weng, Wen-Tsan   +8 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Magnetisation transfer ratio combined with magnetic resonance neurography is feasible in the proximal lumbar plexus using healthy volunteers at 3T

Scientific Reports, 2020
Magnetic resonance neurography (MRN) has been used extensively to study pathological conditions affecting the peripheral nervous system (PNS).
Marios C. Yiannakas, Torben Schneider, Masami Yoneyama, Innocent Aforlabi-Logoh, Ferran Prados, Olga Ciccarelli, Claudia A. M. Wheeler-Kingshott   +6 more
doaj   +1 more source

CD22 modulation alleviates amyloid β-induced neuroinflammation

Neuroinflammation is a crucial driver of multiple neurodegenerative diseases, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD).
Fung, Cheuk Lim, Chong, Chi Ho, Mai, Yu Dong, Zhang, Qingqing, Leung, Shui On   +4 more
core   +1 more source

Neuroinflammation and its Resolution: From Molecular Mechanisms to Therapeutic Perspectives

, 2020
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source