Results 101 to 110 of about 10,500,405 (214)

NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice

eLife, 2018
Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus.
Chrysanthi Fergani, Silvia Leon, Stephanie L Padilla, Anne MJ Verstegen, Richard D Palmiter, Victor M Navarro   +5 more
doaj   +1 more source

Neurokinin B peptide serum levels are higher in normotensive pregnant women than in preeclamptic pregnant women.

, 2003
OBJECTIVES: The purpose of this study was to examine neurokinin B levels in serum from preeclamptic and normotensive and to investigate the role of neurokinin B in preeclampsia.
Schlembach, D;Scalera, F;Fischer, T;Marx, SG;Beinder, E;Garfield, RE
core  

[In Press] Endocytic recycling prevents copper accumulation in astrocytoma cells stimulated with copper-bound neurokinin B

, 2020
Neurokinin B (NKB) is a key neuropeptide in reproductive endocrinology where it contributes to the generation of pulses of gonadotropin-releasing hormone.
Jones, Christopher E. (R15179), Christofides, Katerina (S34306), Menon, Resmi (S33885)   +2 more
core   +1 more source

Effects of Variable Doses of Neurokinin B on Hematological and Coagulation    Parameters in Adult Male Rats

Pakistan Armed Forces Medical Journal
Objective: To evaluate the dose-dependent effects of Neurokinin B on hematological and coagulation parameters in adult male Sprague Dawley rats. Study Design: Laboratory-based experimental study Place and Duration of Study: Gomal University and KMU ...
Faiqah Ramzan, Tahira Atta, Muhammad Waqas Luqman, Muhammad Haris Ramzan   +3 more
doaj   +1 more source

High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons

eLife, 2016
Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (Kiss1ARH) co-express Kiss1, NKB, dynorphin and glutamate and are postulated to provide ...
Jian Qiu, Casey C Nestor, Chunguang Zhang, Stephanie L Padilla, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv   +6 more
doaj   +1 more source

Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse

, 2013
Kisspeptin neurons located in the arcuate nucleus (ARN) coexpress dynorphin and neurokinin B (NKB) and may interact to influence gonadotropin secretion.
de Croft, Simon, Boehm, Ulrich, Herbison, Allan E.   +2 more
core   +1 more source

Suppressive Effects of Glycyrrhetinic Acid Derivatives on Tachykinin Receptor Activation and Hyperalgesia

Journal of Pharmacological Sciences, 2011
.: Glycyrrhetinic acid (GA), an aglycone of glycyrrhizin, isolated from the licorice root (Glycyrrhizia), and its semi-synthetic derivatives have a wide range of pharmacological effects. To investigate whether GA derivatives may be used as a new class of
Yuko Akasaka, Atsushi Sakai, Kumiko Takasu, Michiko Tsukahara, Akira Hatta, Hidenori Suzuki, Hideo Inoue   +6 more
doaj   +1 more source

Placental human neurokinin b precursor

, 2001
Methods of diagnosing pregnancy induced hypertension or pre-eclampsia by the measuremnt of the production of neurokinin B, its precursor and fragments thereof are provided, as are kits for use in the methods.
Lowry, Philip, Page, Nigel
core  

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

The neurokinin B pathway in the treatment of menopausal hot flushes

Climacteric, 2018
Hot flushes remain a debilitating aspect of menopause, disrupting daytime activities and sleep, and may last for years. Estrogen replacement is an effective treatment, but takes time to become maximally effective and is contraindicated in a significant proportion of women, most notably after breast cancer.
Anderson, Richard, Skorupskaite, Karolina, Sassarini, Jenifer   +2 more
openaire   +4 more sources