Results 101 to 110 of about 15,518,026 (208)

Neurokinin B peptide serum levels are higher in normotensive pregnant women than in preeclamptic pregnant women.

, 2003
OBJECTIVES: The purpose of this study was to examine neurokinin B levels in serum from preeclamptic and normotensive and to investigate the role of neurokinin B in preeclampsia.
Schlembach, D;Scalera, F;Fischer, T;Marx, SG;Beinder, E;Garfield, RE
core  

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Kisspeptin and neurokinin B in the regulation of the human hypothalamic-pituitary-gonadal axis [PDF]

, 2017
Background: Hypothalamic kisspeptin and neurokinin B (NKB) are central regulators of GnRH and thus gonadotropin (LH and FSH) secretion. Men and women with loss-of-function mutations in NKB-kisspeptin pathway show hypogonadotropic pubertal delay with ...
Skorupskaite, Karolina
core   +3 more sources

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

International Journal of Cancer, Volume 159, Issue 8, Page 1990-2003, 15 October 2026.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner, Henning Schäffler, Lothar Häberle, Chloë Goossens, Kerstin Pfister, Elena Leinert, Kristina Veselinovic, Sara Y. Brucker, Uwe Köhler, Georg Heinrich, Andreas Schneeweiss, Matthias W. Beckmann, Peter A. Fasching, Wolfgang Janni, Brigitte Rack, Sabine Heublein, Philipp Ziegler   +16 more
wiley   +1 more source

Neuronorm is a potent and water soluble neurokinin A receptor antagonist.

, 1998
We report here the synthesis and preliminary pharmacological characterization of a novel water soluble Neurokinin A receptor antagonist named Neuronorm.
FILIPPELLI, Amelia, C. Pedone, V. Pavone, B. D'Agostino, M. Falciani, LOMBARDI, ANGELINA, A. Lombardi, M. G. Matera, F. Rossi, M. De Rosa, A. FILIPPELLI, B. DAGOSTINO, PAVONE, VINCENZO, Mario De Rosa, Angela Lombardi, Carlo Pedone, Francesco Rossi, Bruno D'Agostino, Maddalena Falciani, Vincenzo Pavone, Amelia Filippelli, Maria Gabriella Matera   +21 more
core   +1 more source

NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice

eLife, 2018
Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus.
Chrysanthi Fergani, Silvia Leon, Stephanie L Padilla, Anne MJ Verstegen, Richard D Palmiter, Victor M Navarro   +5 more
doaj   +1 more source

The tachykinin peptide neurokinin B binds copper(I) and silver(I) and undergoes quasi-reversible electrochemistry : towards a new function for the peptide in the brain

, 2014
The tachykinin neuropeptide family, which includes substance P and neurokinin B, is involved in a wide array of biological functions. Among these is the ability to protect against the neurotoxic processes in Alzheimer’s Disease, but the mechanisms ...
Williams, Peter A. (R8843), Jones, Christopher E. (R15179), Grosas, Aidan B. (S30549), Kalimuthu, Palraj, Bernhardt, Paul V., Millar, Thomas (R8217), Smith, Alison C.   +6 more
core   +1 more source

Effects of Variable Doses of Neurokinin B on Hematological and Coagulation    Parameters in Adult Male Rats

Pakistan Armed Forces Medical Journal
Objective: To evaluate the dose-dependent effects of Neurokinin B on hematological and coagulation parameters in adult male Sprague Dawley rats. Study Design: Laboratory-based experimental study Place and Duration of Study: Gomal University and KMU ...
Faiqah Ramzan, Tahira Atta, Muhammad Waqas Luqman, Muhammad Haris Ramzan   +3 more
doaj   +1 more source

High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons

eLife, 2016
Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (Kiss1ARH) co-express Kiss1, NKB, dynorphin and glutamate and are postulated to provide ...
Jian Qiu, Casey C Nestor, Chunguang Zhang, Stephanie L Padilla, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv   +6 more
doaj   +1 more source

Suppressive Effects of Glycyrrhetinic Acid Derivatives on Tachykinin Receptor Activation and Hyperalgesia

Journal of Pharmacological Sciences, 2011
.: Glycyrrhetinic acid (GA), an aglycone of glycyrrhizin, isolated from the licorice root (Glycyrrhizia), and its semi-synthetic derivatives have a wide range of pharmacological effects. To investigate whether GA derivatives may be used as a new class of
Yuko Akasaka, Atsushi Sakai, Kumiko Takasu, Michiko Tsukahara, Akira Hatta, Hidenori Suzuki, Hideo Inoue   +6 more
doaj   +1 more source