Results 111 to 120 of about 15,518,026 (208)

Neurokinin B and serum albumin limit copper binding to mammalian gonadotropin releasing hormone

, 2018
Gonadotropin releasing hormone (GnRH) triggers secretion of luteinizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary gland. GnRH is able to bind copper, and both invitro and invivo studies have suggested that
Jones, Christopher E. (R15179), Kevin K. Tran, Tran, Kevin K., Ahmad Samir Gul, Christopher E. Jones, Gul, Ahmad S.   +5 more
core   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

The role of kisspeptin/neurokinin B/dynorphin neurons in pathomechanism of vasomotor symptoms in postmenopausal women: from physiology to potential therapeutic applications

, 2018
Women during perimenopausal period experience a range of symptoms, which interfere with physical, sexual, and social life. About 65–75% of symptoms connected with postmenopausal period are vasomotor symptoms (VMS), such as hot flushes and night sweats ...
Czyzyk A., Szeliga A., Meczekalski B., Podfigurna A., Genazzani A. R., Genazzani A. D., Adam Czyzyk, Agnieszka Podfigurna, Alessandro D. Genazzani, Blazej Meczekalski, Anna Szeliga, Andrea R. Genazzani   +11 more
core   +1 more source

Projection neurons in lamina III of the rat spinal cord are selectively innervated by local dynorphin-containing excitatory neurons [PDF]

, 2012
Large projection neurons in lamina III of the rat spinal cord that express the neurokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents. However, we know little about
Todd, A.J., Polgar, Erika, Furuta, T., Watanabe, M., Baseer, N., Todd, A., Kaneko, T.   +6 more
core   +1 more source

The neurokinin B pathway in the treatment of menopausal hot flushes

Climacteric, 2018
Hot flushes remain a debilitating aspect of menopause, disrupting daytime activities and sleep, and may last for years. Estrogen replacement is an effective treatment, but takes time to become maximally effective and is contraindicated in a significant proportion of women, most notably after breast cancer.
Anderson, Richard, Skorupskaite, Karolina, Sassarini, Jenifer   +2 more
openaire   +4 more sources

The Inhibitory Effects of Neurokinin B on GnRH Pulse Generator Frequency in the Female Rat

, 2012
Neurokinin B (NKB) and its receptor (neurokinin-3 receptor) are coexpressed with kisspeptin and dynorphin A (Dyn) within neurons of the hypothalamic arcuate nucleus, the suggested site of the GnRH pulse generator.
James S. Kinsey-Jones, Grachev, P, O'Byrne, KT, Lin, Yuan Shao, Li, Xiao Feng, Grachev, Pasha, Milligan, SR, Pasha Grachev, Stafford L. Lightman, Xiao Feng Li, Kinsey-Jones, JS, Lightman, Stafford L., Lightman, SL, O'Byrne, Kevin, Li, XF, Yuan Shao Lin, Lin, YS, Stuart R. Milligan, Kinsey-Jones, James S., Kevin T. O'Byrne, Milligan, Stuart R.   +20 more
core   +1 more source

Genetics of Idiopathic Hypogonadotropic Hypogonadism

JCRPE
Idiopathic hypogonadotropic hypogonadism (IHH) comprises a group of disorders characterized by deficient secretion or action of gonadotropin-releasing hormone (GnRH), leading to impaired pubertal development and infertility.
A. Kemal Topaloğlu, Leman Damla Kotan
doaj   +1 more source

Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin

Frontiers in Endocrinology, 2019
Pubertal onset is thought to be timed by an increase in pulsatile gonadotropin-releasing hormone (GnRH)/gonadotropin secretion in mammals. The underlying mechanism of pubertal onset in mammals is still an open question.
Yoshihisa Uenoyama, Naoko Inoue, Sho Nakamura, Hiroko Tsukamura   +3 more
doaj   +1 more source

Assessment of Relationship of Serum Neurokinin-B Level in the Pathophysiology of Pre-eclampsia: A Case–Control Study

, 2018
Introduction Pre-eclampsia is a pregnancy-induced disorder that complicates approximately 5–7% of pregnancies. It is the leading cause of maternal and foetal morbidity and mortality worldwide. Aim To determine the role of serum neurokinin-B level in
Aziz A., Asma Aziz, Ali A., Vitale S. G., Henna Salman, Salman H., Shah M., Mohsin Shah, Salvatore Giovanni Vitale, Asif Ali   +9 more
core   +1 more source

Effect of neurokinin 3 receptor agonist senktide on the activation of hypothalamic nNOS neurons in cycling female rats

Asian Pacific Journal of Reproduction
Objective: To examine the effect of an neurokinin 3 receptor (NK3R) agonist, senktide, on neuronal nitric oxide synthase (nNOS) activation in the median eminence-arcuate nucleus (ME-ARC) and preoptic area (POA) regions of the hypothalamus across ...
Vikash Prashar, Tania Arora, Randeep Singh, Arti Sharma, Jyoti Parkash   +4 more
doaj   +1 more source