Results 91 to 100 of about 15,518,026 (208)

Neurokinin B signaling in puberty: Human and animal studies

, 2010
PubMedID: 20176081Recent reports of humans who have normosmic idiopathic hypogonadotropic hypogonadism due to TAC3 or TACR3 (encoding neurokinin B and its receptor, NK3R, respectively) mutations provided compelling evidence for the involvement of ...
Topaloglu A.K., A. Kemal Topaloglu
core   +1 more source

The efficacy of a newly developed neurokinin 3 receptor agonist B21-750 on luteinizing hormone secretion in cycling goats

The Journal of Reproduction and Development, 2019
This study aimed to investigate the efficacy of a newly developed NK3 receptor agonist (B21-750) on the secretion of luteinizing hormone (LH) in association with ovarian steroid hormones during the follicular phase (FP, n = 5) and luteal phase (LP, n = 5)
Larasati Puji RAHAYU, Natsumi ENDO, Shinji KUWAI, Shinya OISHI, Tomomi TANAKA   +4 more
doaj   +1 more source

Actions of tachykinins on the rabbit mesenteric artery: substance P and [Glp6,L-Pro9]SP6-11 are potent agonists for endothelial neurokinin-1 receptors

, 1989
1. Identification of the subtype of neurokinin receptor on the endothelium of the rabbit mesenteric artery was demonstrated by comparing the relative potencies of the naturally occurring tachykinins, substance P, neurokinin A and neurokinin B and the ...
Geoffrey Burnstock, Burnstock, G., Stewart-Lee, A.; id_orcid, Anne Stewart-Lee   +3 more
core   +1 more source

Physiological Functions and Molecular Mechanisms of Neurokinin B in Fish

Progress in Fishery Sciences
Neurokinin B (NKB) is a hypothalamic neuropeptide containing 10 amino acids and is an essential member of the tachykinin family. Based on studies in mammals, Kiss, NKB, and dynorphin A are located in the common neurons, named KNDy neurons, and NKB and ...
Bin WANG, Zhenfang TIAN, Huiying GUO, Yongjiang XU, Aijun CUI, Yan JIANG   +5 more
doaj   +1 more source

German wine and respiration: Remarks on the discovery, properties and significance of the Bötzinger complex

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram of the proposed and documented functions of the Bötzinger complex (BötC; highlighted in yellow) and its inhibitory synaptic connectivity with the pre‐Bötzinger complex (preBötC). The BötC was named after wine bottles served at the conference dinner of a meeting held in Germany (image source: https ...
Janusz Lipski
wiley   +1 more source

Placental human neurokinin b precursor

, 2001
Methods of diagnosing pregnancy induced hypertension or pre-eclampsia by the measuremnt of the production of neurokinin B, its precursor and fragments thereof are provided, as are kits for use in the methods.
Lowry, Philip, Page, Nigel
core  

Senktide, a selective neurokinin B-like agonist, elicits serotonin-mediated behaviour following intracisternal administration in the mouse.

, 2016
Behavioural responses to tachykinins were observed following intracisternal administration in mice. The synthetic NK-3 agonists senktide and L-363,851 caused behaviour typically associated with serotonergic stimulation, including head twitches ...

core   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, Volume 65, Issue 12, Page 2497-2508, December 2026.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Neurokinin A-induced Ca²⁺-responses in mouse taste cells involve activation of both the neurokinin 1 and neurokinin 2 receptors.

, 2013
A, Inhibition of Ca2+- responses to neurokinin A (NKA, 300 nM) in an isolated taste cell by the neurokinin 2 receptor (NK-2R) antagonist GR159897 (GR,1 µM) and the neurokinin 1 receptor (NK-1R) antagonist RP67580 (RP, 1 µM).
Jeff Grant (331942)
core   +1 more source

Arcuate kisspeptin neurons display two types of calcium events: Regulation by sex, gonads, and senktide

Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract The pattern of gonadotropin‐releasing hormone (GnRH) release controls reproduction in vertebrates and is regulated by feedback from the gonads. Evidence is accumulating that steroid‐sensitive hypothalamic arcuate kisspeptin–neurokinin B–dynorphin (KNDy) neurons drive GnRH pulses.
R. Anthony DeFazio, Christian R. Burgess, Laura L. Burger, Amanda G. Gibson, Suzanne M. Moenter   +4 more
wiley   +1 more source