Results 71 to 80 of about 10,500,405 (214)

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Placental neurokinin B mRNA expression increases at preterm labor

, 2007
Introduction: Neurokinin B (NKB) is a neuropeptide belonging to the family of tachykinins-related peptides that elicits contractility of human myometrial strips in vitro.
FLORIO, P., F.M. Reis, E. Leucci, G. De Falco, LEONCINI, L., TORRES, P. B., TORRICELLI, M., F. Petraglia, REIS, F. M., GIOVANNELLI, A., P. Florio, P.B. Torres, A. Giovannelli, PETRAGLIA, F., L. Leoncini, M. Torricelli, LEUCCI, E., DE FALCO, G.   +17 more
core   +1 more source

Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models [PDF]

, 2007
It has been proposed that substance P and calcitonin gene-related peptide (CGRP) are upregulated in low-threshold myelinated primary afferents after certain types of nerve injury, and that release of substance P from these afferents contributes to the ...
Todd, A.J., Riddell, J.S., Scott, D.T., Hughes, D.I.   +3 more
core   +2 more sources

Decoding the molecular and structural determinants of the neurokinin A and Aβ1-42 peptide cross-interaction in the amyloid cascade pathway

iScience
Summary: Tachykinins are short neuropeptides, such as substance P and neurokinin B, that have been shown to interact with Alzheimer’s β-amyloid (Aβ) peptide.
Mohsen Habibnia, Eric Catalina-Hernandez, Mario Lopez-Martin, David Masnou-Sanchez, Alex Peralvarez-Marin   +4 more
doaj   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Neurokinin B signaling in puberty: Human and animal studies

, 2010
PubMedID: 20176081Recent reports of humans who have normosmic idiopathic hypogonadotropic hypogonadism due to TAC3 or TACR3 (encoding neurokinin B and its receptor, NK3R, respectively) mutations provided compelling evidence for the involvement of ...
Topaloglu A.K.
core   +1 more source

Molecular characterisation, expression and localisation of human neurokinin-3 receptor [PDF]

, 1992
The complete amino acid sequence of the human neurokinin-3 receptor was deduced by DNA sequence analysis of human genomic fragments. Comparison of the predicted primary structure with those for the human neurokinin receptors 1 and 2 shows a highly ...
Arkinstall, S.J., Adami, N., Kawashima, E., N. Adami, E. Kawashima, S.J. Arkinstall, Schulz, M.F., Missotten, M., Talabot, F., M.F. Schulz, K. Maury, Buell, G., Maury, K., F. Talabot, G. Buell, M. Missotten   +15 more
core   +1 more source

Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproduction [PDF]

Proceedings of the National Academy of Sciences, 2012
The endocrine regulation of vertebrate reproduction is achieved by the coordinated actions of several peptide neurohormones, tachykinin among them. To study the evolutionary conservation and physiological functions of neurokinin B (NKB), we identified tachykinin ( tac ) and
Jakob, Biran, Ori, Palevitch, Shifra, Ben-Dor, Berta, Levavi-Sivan   +3 more
openaire   +2 more sources

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

New Insights into the Control of Pulsatile GnRH Release: the Role of Kiss1/Neurokinin B Neurons

Frontiers in Endocrinology, 2012
Gonadotropin-releasing hormone (GnRH) is the ultimate output signal of an intricate network of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release.
Víctor M. Navarro
doaj   +1 more source