Results 51 to 60 of about 10,500,405 (214)

Neurokinin B levels in maternal circulation during early pregnancy

, 2004
Neurokinin B levels were measured between the 10th-20th weeks of pregnancy, i.e., prior to the development of clinical symptoms, in women who developed preeclampsia or delivered a growth-restricted baby.
Tjoa, May Lee, Oudejans, Cees B M, van Wijk, Inge J, Blankenstein, Marinus A, Lomecky, Marie, van Vugt, John M G, Martens, Frans   +6 more
core   +1 more source

The Role of Neurokinin B Signalling in Reproductive Neuroendocrinology [PDF]

Neuroendocrinology, 2013
The KNDy neuropeptides, kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn), have been implicated in regulating pulsatile luteinising hormone (LH) secretion. Studies of the interactions between KNDy signalling systems, however, are currently few.
Grachev, P, Millar, R P, O'Byrne, K T
openaire   +4 more sources

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Mapping of neurokinin b in the cat brainstem [PDF]

, 2020
We studied the distribution of neurokinin B-immunoreactive cell bodies and fibers in the cat brainstem using an indirect immunoperoxidase technique. The highest density of immunoreactive fibers was found in the motor trigeminal nucleus, the laminar and ...
Ae J A Narvaez, L A Aguilar, J Rioja, I Cuadrado, Sabio, Incyl, Ae R Coven˜as, Alfonso X El, Ae J Rioja, Ae J A Aguirre, Anat Embryol, J A Aguirre, Ae L A Aguilar   +12 more
core  

Neurokinin B is hydrolysed by synaptic membranes and by endopeptidase-24.11 (‘enkephalinase’) but not by angiotensin converting enzyme [PDF]

, 1985
Endopeptidase-24.11 (‘enkephalinase’, EC 3.4.24.11) from pig kidney hydrolysed neurokinin B at 4 sites:The major site of hydrolysis was the Gly8-Leu9 bond.
Hooper, Nigel M., Turner, Anthony J., Anthony J. Turner, Nigel M. Hooper   +3 more
core   +1 more source

Beyond leptin: emerging candidates for the integration of metabolic and reproductive function during negative energy balance

Frontiers in Endocrinology, 2011
Reproductive status is tightly coupled to metabolic state in females, and ovarian cycling in mammals is halted when energy output exceeds energy input, a metabolic condition known as negative energy balance.
Cadence eTrue, Kevin eGrove, M Susan eSmith   +2 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Modeling temporal lobe epilepsy with hippocampal sclerosis in rats using the selective neurotoxin stable substance P‐saporin

Epilepsia, EarlyView.
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta, Mitchell T. Kesler, Morris H. Scantlebury, Robert S. Sloviter, G. Campbell Teskey   +4 more
wiley   +1 more source

Serum neurokinin B levels in newly diagnosed nondipper hypertensive patients

, 2015
Objective Cardiovascular diseases are more common in patients with nondipper hypertension (NDHT) compared with those with dipper hypertension (DHT). The aim of this study is to evaluate the serum neurokinin B levels in DHT and NDHT patients.
Erselcan, Kubilay, Akkoyun, Dursun Çayan, Akyüz, Aydın, Alpsoy, Şeref, Aydın, Murat   +4 more
core   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source