Response of Pituitary Cells and Tissues to Neurokinin B and F in the Nile tilapia [PDF]
Dev Reprod, 2022 Neurokinin B (NKB) is a neuropeptide involved in the regulation of reproductive endocrine system of vertebrate animals, including fish. However, the pathway of NKB action in fish has not been clearly elucidated.
Seong Hee Mun, H. J. Oh, J. Kwon
semanticscholar +4 more sources
Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes [PDF]
Journal of Veterinary ResearchThe hypothalamic neuropeptides kisspeptin-10 (KiSS-10), neurokinin B (NKB), and dynorphin A (Dyn A) play roles in the endocrine regulation of the hypothalamic–pituitary–ovarian (HPO) axis in puberty.
Szysiak Natalia +7 more
doaj +3 more sources
Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice [PDF]
Sci Rep, 2019 Neurons in the hypothalamic arcuate nucleus (ARC) that co-express kisspeptin, neurokinin B and dynorphin (KNDy cells) are essential for mammalian reproduction as key regulators of gonadotropin-releasing hormone (GnRH) secretion.
Aleisha M. Moore, L. Coolen, M. Lehman
semanticscholar +3 more sources
Expression of genes for Kisspeptin (KISS1), Neurokinin B (TAC3), Prodynorphin (PDYN), and gonadotropin inhibitory hormone (RFRP) across natural puberty in ewes [PDF]
Physiol Rep, 2020 Expression of particular genes in hypothami of ewes was measured across the natural pubertal transition by in situ hybridization. The ewes were allocated to three groups (n = 4); prepubertal, postpubertal and postpubertally gonadectomized (GDX ...
Qun Li +5 more
semanticscholar +3 more sources
Role of Kisspeptin and Neurokinin B Signaling in Male Rhesus Monkey Puberty. [PDF]
Endocrinology, 2018 Despite the well-established concept that an increase in pulsatile GnRH release triggers puberty, the precise signaling mechanism responsible for the pubertal increase in GnRH release remains unclear.
James P. Garcia +4 more
semanticscholar +3 more sources
Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health [PDF]
J Neuroendocrinol, 2022 The reproductive neuropeptide kisspeptin has emerged as the master regulator of mammalian reproduction due to its key roles in the initiation of puberty and the control of fertility.
E. Mills, W. Dhillo
semanticscholar +2 more sources
Essential Role of Histidine for Rapid Copper(II)-Mediated Disassembly of Neurokinin B Amyloid [PDF]
Biomolecules, 2022 Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core secretory vesicles within hypothalamic neurons ...
Bhawantha M. Jayawardena +3 more
doaj +2 more sources
Neurokinin B and pre-eclampsia: a decade of discovery [PDF]
Reproductive Biology and Endocrinology, 2010 At the start of the last decade, we provided evidence that levels of the peptide neurokinin B were highly elevated in pre-eclampsia. We hypothesized that elevated levels of neurokinin B may be an indicator of pre-eclampsia and that treatment with certain
Page Nigel M
doaj +2 more sources
Assessing the effects of menopause and obesity on matriptase-2 and neurokinin B concentrations: A cross-sectional study [PDF]
Journal of Medical BiochemistryBackground: Matriptase-2 (MT2) is implicated in iron metabolism, obesity, insulin resistance, and glucose homeostasis. Neurokinin B (NKB) plays a crucial role in gonadotropin secretion, which is essential for reproduction.
Bulut Arikan Funda, Sagsoz Nevin
doaj +2 more sources
Neurokinin B-Expressing Neurons of the Central Extended Amygdala Mediate Inhibitory Synaptic Input onto Melanin-Concentrating Hormone Neuron Subpopulations [PDF]
J Neurosci, 2021 The lateral hypothalamic area (LHA) is a highly conserved brain region critical for maintaining physiological homeostasis and goal-directed behavior.
Akie Fujita +7 more
semanticscholar +2 more sources