Results 21 to 30 of about 12,605,538 (213)

Undernutrition reduces kisspeptin and neurokinin B expression in castrated male sheep [PDF]

Reprod Fertil, 2020
Summary Undernutrition impairs reproductive success through suppression of gonadotropin-releasing hormone (GnRH), and subsequently luteinizing hormone (LH), secretion.
C. M. Merkley, Allison N Renwick, Sydney L. Shuping, K. Harlow, Jeffrey R. Sommer, Casey C Nestor   +5 more
semanticscholar   +2 more sources

Kisspeptin and neurokinin B interactions in modulating gonadotropin secretion in women with polycystic ovary syndrome [PDF]

Hum Reprod, 2020
STUDY QUESTION What is the role of the hypothalamic neuropeptide neurokinin B (NKB) and its interaction with kisspeptin on GnRH/LH secretion in women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER Administration of neurokinin 3 receptor antagonist
K. Skorupskaite, J. George, J. Veldhuis, R. Millar, R. Anderson   +4 more
semanticscholar   +2 more sources

Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]

, 2012
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Bloom, Stephen R., Borsay, Beáta Á., Ciofi, Philippe, Dhillo, Waljit S., Ghatei, Mohammad A., Herczeg, László, Hrabovszky, Erik, Liposits, Zsolt, Molnár, Csilla S., Rácz, Kálmán, Sipos, Máté T., Vida, Barbara   +11 more
core   +3 more sources

Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro [PDF]

Journal of Veterinary Research
Neurokinin B (NKB), dynorphin A (Dyn A) and kisspeptin (KiSS) are key agents that participate in the neuroendocrine regulation of the development and functioning of the reproductive system.
Szysiak Natalia, Kosior-Korzecka Urszula, Greguła-Kania Monika, Patkowski Krzysztof, Fila Mateusz, Junkuszew Andrzej   +5 more
doaj   +2 more sources

Expression of Neurokinin B Receptor in the Gingival Squamous Cell Carcinoma Bone Microenvironment [PDF]

Diagnostics, 2021
Gingival squamous cell carcinoma (SCC) frequently invades the maxillary or mandibular bone, and bone destruction is known as a key prognostic factor in gingival SCCs.
Shoko Yoshida, Tsuyoshi Shimo, Kiyofumi Takabatake, Yurika Murase, Kyoichi Obata, Tatsuo Okui, Yuki Kunisada, Soichiro Ibaragi, Hitoshi Nagatsuka, Akira Sasaki   +9 more
doaj   +2 more sources

Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep.

Endocrinology, 2020
Evidence suggests that the hypothalamic-pituitary-gonadal (HPG) axis is active during the critical period for sexual differentiation of the ovine sexually dimorphic nucleus, which occurs between gestational day (GD) 60 and 90.
R. Amodei, Kyle P. Gribbin, W. He, I. Lindgren, Keely R. Corder, S. Jonker, C. Estill, L. Coolen, M. Lehman, W. Whitler, F. Stormshak, C. Roselli   +11 more
semanticscholar   +2 more sources

A New Hope for Woman with Vasomotor Symptoms: Neurokinin B Antagonists [PDF]

J Clin Med
KNDy (kisspeptine, neurokinin B, dynorphin) neurons, located in the hypothalamus, play a crucial role in the development of vasomotor symptoms (VSM) in menopausal women.
Błażej Męczekalski, Anna Kostrzak, Christian Unogu, Stefania Bochynska, M. Maciejewska-Jeske, G. Bala, A. Szeliga   +6 more
semanticscholar   +2 more sources

Investigating the KNDy hypothesis in humans by co-administration of kisspeptin, neurokinin B and naltrexone in men [PDF]

J Clin Endocrinol Metab, 2016
Context: A subpopulation of hypothalamic neurons co-localise three neuropeptides namely kisspeptin, neurokinin B (NKB) and dynorphin collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis);
Abbara, A, Bassett, P, Bloom, S, COMNINOS, A, Dhillo, WS, Jayasena, C, Mizamtsidi, M, Narayanaswamy, S, Papadopoulou, D, Prague, J, Shah, A, Veldhuis, J   +11 more
core   +2 more sources

Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling.

J Clin Endocrinol Metab, 2019
CONTEXT Kisspeptin-Neurokinin B-Dynorphin neurons are critical regulators of the hypothalamic-pituitary-gonadal axis. Neurokinin B (NKB) and dynorphin are hypothesized to influence the frequency of gonadotropin-releasing hormone (GnRH) pulses; whereas ...
Margaret F. Lippincott, S. León, Yee-Ming Chan, Yee-Ming Chan, C. Fergani, Rajae Talbi, I. Farooqi, Christopher M. Jones, Wiebke Arlt, Wiebke Arlt, Wiebke Arlt, S. Stewart, T. Cole, E. Terasawa, J. Hall, N. Shaw, V. Navarro, S. Seminara   +17 more
semanticscholar   +2 more sources

Expression of Kisspeptin, Neurokinin B, and Dynorphin During Pubertal Development in Female Sheep [PDF]

J Endocr Soc, 2021
Eliana G Aerts, KaLynn Harlow, Max J Griesgraber, Elizabeth C. Bowdridge, Steven L. Hardy, Casey C Nestor, Stanley M. Hileman   +6 more
openalex   +2 more sources