Results 11 to 20 of about 15,518,026 (208)
Neurokinin B and pre-eclampsia: a decade of discovery [PDF]
Reproductive Biology and Endocrinology, 2010 At the start of the last decade, we provided evidence that levels of the peptide neurokinin B were highly elevated in pre-eclampsia. We hypothesized that elevated levels of neurokinin B may be an indicator of pre-eclampsia and that treatment with certain
Page Nigel M
doaj +6 more sources
Neurokinin B Signalling in Human Puberty [PDF]
Journal of Neuroendocrinology, 2010 Recent identification ofTAC3orTACR3(encoding neurokinin B and its receptor, NK3R, respectively) mutations as the causes of normosmic idiopathic hypogonadotrophic hypogonadism has provided compelling evidence for the involvement of neurokinin B (NKB) signalling in puberty.
A K, Topaloglu, L D, Kotan, B, Yuksel
openaire +3 more sources
Effect of kassinin, neurokinin A and neurokinin B on drinking behaviour in the pigeon
Regulatory Peptides, 1987 Intracerebroventricular (i.c.v.) injection of kassinin produced a prompt and copious drinking response at doses of 10-1000 ng/pigeon, in the absence of other behavioural alterations or of changes in core temperature. Neurokinin A and B evoked drinking, but they were respectively 10 and 100 times less potent than kassinin.
MASSI, Maurizio +3 more
core +5 more sources
The Emerging Therapeutic Potential of Kisspeptin and Neurokinin B
Endocrine Reviews, 2023 Abstract Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) neuronal activity and pulsatile GnRH secretion. Their critical role in reproductive health was first identified after inactivating variants in genes encoding ...
Waljit S Dhillo +2 more
exaly +4 more sources
Neurokinin B signalling in the human reproductive axis
Molecular and Cellular Endocrinology, 2011 Recent human genetic studies have established that neurokinin B (NKB) signalling via the neurokinin 3 receptor (NK3R) is required for normal developmental activation of pulsatile GnRH secretion from the hypothalamus. As increasing numbers of patients with loss-of-function mutations have been described, evidence has emerged that peripheral NKB is not ...
Topaloglu, A. Kemal, Semple, Robert K.
core +5 more sources
Alteration of Neurokinin B Gene Expression and Hypothalamic-Pituitary- Gonadal Axis in Response to One-month Regular Moderate Physical Activity [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017 Background: The advantageous effects of the regular moderate physical activity (Exercise) on reproduction is widely accepted, but until now, the alterations of the expression of hypothalamic arcuate nuclei gene affecting on reproduction axis in response ...
Nazli Khajehnasiri +2 more
doaj +1 more source
Role of Kisspeptin and Neurokinin B in Puberty in Female Non-Human Primates [PDF]
Frontiers in Endocrinology, 2018 In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty.
Ei Terasawa +4 more
doaj +2 more sources
A New Hope for Woman with Vasomotor Symptoms: Neurokinin B Antagonists. [PDF]
J Clin MedKNDy (kisspeptine, neurokinin B, dynorphin) neurons, located in the hypothalamus, play a crucial role in the development of vasomotor symptoms (VSM) in menopausal women.
Meczekalski B +6 more
europepmc +2 more sources
Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health. [PDF]
J Neuroendocrinol, 2022 The reproductive neuropeptide kisspeptin has emerged as the master regulator of mammalian reproduction due to its key roles in the initiation of puberty and the control of fertility.
Mills EG, Dhillo WS.
europepmc +2 more sources
Romanian Medical Journal, 2021 Hot flashes (HF), transitory episodes of erythema, heat sensation, anxiety followed by chills, are described in carcinoid syndrome, mastocytosis, medullary thyroid cancer, hyperthyroidism, pheochromocytoma, alcohol consumption, side effects of drugs, and
Florica Sandru +7 more
doaj +1 more source