Results 41 to 50 of about 11,252 (195)
Neurokinin B Analogs Substituted with Glycine [PDF]
Bulletin of the Chemical Society of Japan, 1986 Abstract Four Neurokinin B analogs substituted with glycine at position 4, 5, 6, or 7 were synthesized by Merrifield’s solid phase method. Pharmacological property of the analogs is described. The results suggest that Phe6 and Val7 residues may be essential for intrinsic activity on smooth muscle.
Tadashi Hashimoto +2 more
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Decreased neurokinin B as a risk factor of functional hypothalamic amenorrhea
Gynecological Endocrinology, 2023 Background Neurokinin B (NKB) belongs to the tachykinin family of proteins who’s regulation is essential for proper function of the reproductive system.
Anna Szeliga +3 more
doaj +1 more source
Role of neurokinin B in ovine puberty
Domestic Animal Endocrinology, 2020 Puberty is the process whereby an individual acquires the ability to reproduce, and the attainment of puberty in a timely manner is critical for both humans and livestock. For livestock, the initiation of puberty at the appropriate time aids in increasing lifetime productivity, thus maximizing profitability for producers.
M.N. Bedenbaugh +2 more
openaire +3 more sources
Neurokinin receptors in the gastrointestinal muscle wall: cell distribution and possible roles
Biomolecular Concepts, 2013 The neurokinin receptors are G-protein-linked receptors; three distinct molecules, called neurokinin-1, neurokinin-2, and neurokinin-3 receptors, have been identified.
Vannucchi Maria Giuliana +1 more
doaj +1 more source
A Neural Circuit Underlying the Generation of Hot Flushes
Cell Reports, 2018 Summary: Hot flushes are a sudden feeling of warmth commonly associated with the decline of gonadal hormones at menopause. Neurons in the arcuate nucleus of the hypothalamus that express kisspeptin and neurokinin B (Kiss1ARH neurons) are candidates for ...
Stephanie L. Padilla +4 more
doaj +1 more source
Fertility & Reproduction, 2022 Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine condition affecting up to 20% of reproductively aged women worldwide. Owing to an ambiguous etiology and complicated pathophysiology, current PCOS treatments remain purely ...
Irene E. SUCQUART +12 more
doaj +1 more source
An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis [PDF]
The Journal of Cell Biology, 2006 Establishment of angiogenic circuits that orchestrate blood vessel development and remodeling requires an exquisite balance between the activities of pro- and antiangiogenic factors. However, the logic that permits complex signal integration by vascular endothelium is poorly understood.
Pal, Saumen +10 more
openaire +2 more sources
Autocrine regulation of human sperm motility by tachykinins
Reproductive Biology and Endocrinology, 2010 Background We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa.
Pinto Francisco M +7 more
doaj +1 more source
Therapeutic Advances in Reproductive Health, 2023 Vasomotor symptoms of menopause (VMS), otherwise known as hot flashes, can significantly impact women’s quality of life. Up to 87% of women report hot flashes during or after their menopause transition, and can last for a median duration of 7.4 years ...
Melissa Conklin, Nanette Santoro
doaj +1 more source
The effects of supraphysiological levels of testosterone on neural networks upstream of gonadotropin-releasing hormone neurons [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Several pathological conditions are associated with hyper-production of testosterone; however, its impacts are not well understood. Hence, we evaluated the effects of supraphysiological levels of testosterone on gonadotropin-releasing ...
Mohammad Saied Salehi +3 more
doaj +1 more source