Results 51 to 60 of about 12,605,538 (213)

The organisation of spinoparabrachial neurons in the mouse [PDF]

open access: yes, 2015
The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception.
Cameron, Darren   +5 more
core   +1 more source

Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice

open access: yesCell Reports, 2023
Summary: The mechanism by which arcuate nucleus kisspeptin (ARNKISS) neurons co-expressing glutamate, neurokinin B, and dynorphin intermittently synchronize their activity to generate pulsatile hormone secretion remains unknown.
Su Young Han   +7 more
doaj   +1 more source

Tachykinin neuropeptides in cerebellar granule neurons: an immunocytochemical study

open access: yesEuropean Journal of Histochemistry, 2009
We previously demonstrated that exogenously administered neurokinin A and neurokinin B, but not substance P, increased the sensitivity of cultured cerebellar granule neurons (CGNs) to glutamate.
C Barbato, MT Ciotti
doaj   +1 more source

The Role of the Brain in the Pathogenesis and Physiology of Polycystic Ovary Syndrome (PCOS). [PDF]

open access: yes, 2019
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder, affecting at least 10% of women of reproductive age. PCOS is typically characterized by the presence of at least two of the three cardinal features of hyperandrogenemia (high ...
Coutinho, Eulalia A   +1 more
core   +1 more source

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. [PDF]

open access: yes, 2020
Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones.
Biglia, Nicoletta   +14 more
core   +4 more sources

Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows

open access: yesThe Journal of Reproduction and Development, 2022
The reproductive performance of dairy cows has declined, along with an increase in their milk yield. First-service conception rates in lactating dairy cows are often lower than 50%.
Natsumi ENDO
doaj   +1 more source

The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism

open access: yesJournal of Neuroinflammation, 2011
Background Neurogenic inflammation is orchestrated by a large number of neuropeptides. Tachykinins (substance P, neurokinin A and neurokinin B) are pro-inflammatory neuropeptides that may play an important role in some autoimmune neuroinflammatory ...
Mostafa Gehan A, AL-Ayadhi Laila Y
doaj   +1 more source

Proteomic and phosphoproteomic analysis reveals that neurokinin-1 receptor (NK1R) blockade with aprepitant in human keratinocytes activates a distinct subdomain of EGFR signaling: Implications for the anti-pruritic activity of NK1R antagonists [PDF]

open access: yes, 2019
Background: Epidermal growth factor receptor (EGFR) inhibitors can cause serious cutaneous toxicities, including pruritus and papulopustular acneiform skin eruptions.
Boozalis, Emily   +10 more
core   +2 more sources

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

open access: yes, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core   +1 more source

Neuropeptide modulation of lymphatic smooth muscle tone in the canine forelimb

open access: yesMediators of Inflammation, 1992
Neurokinin A and B are putative inflammatory mediators. We assessed their ability to alter prenodal lymphatic resistance. Intralymphatic neurokinin A (3.0 × 10−6, 3.0 × 10−5 and 3.0 × 10−4 mol l−1) significantly constricted lymphatics at the two highest ...
David E. Dobbins
doaj   +1 more source

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