Results 61 to 70 of about 12,605,538 (213)

Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones [PDF]

open access: yes, 2011
Peer reviewedPublisher ...
Davidson, Scott   +4 more
core   +4 more sources

Neurokinin receptors in the gastrointestinal muscle wall: cell distribution and possible roles

open access: yesBiomolecular Concepts, 2013
The neurokinin receptors are G-protein-linked receptors; three distinct molecules, called neurokinin-1, neurokinin-2, and neurokinin-3 receptors, have been identified.
Vannucchi Maria Giuliana   +1 more
doaj   +1 more source

A Neural Circuit Underlying the Generation of Hot Flushes

open access: yesCell Reports, 2018
Summary: Hot flushes are a sudden feeling of warmth commonly associated with the decline of gonadal hormones at menopause. Neurons in the arcuate nucleus of the hypothalamus that express kisspeptin and neurokinin B (Kiss1ARH neurons) are candidates for ...
Stephanie L. Padilla   +4 more
doaj   +1 more source

Pharmacological Antagonism of the Kisspeptin-Neurokinin System Improved Adverse Metabolic Traits in a PCOS Mouse Model

open access: yesFertility & Reproduction, 2022
Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine condition affecting up to 20% of reproductively aged women worldwide. Owing to an ambiguous etiology and complicated pathophysiology, current PCOS treatments remain purely ...
Irene E. SUCQUART   +12 more
doaj   +1 more source

Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]

open access: yes, 2017
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R.   +5 more
core   +1 more source

Colocalization of Cocaine- and Amphetamine-Regulated Transcript with Kisspeptin and Neurokinin B in the Human Infundibular Region [PDF]

open access: gold, 2019
Bloom, Stephen R.   +8 more
core   +3 more sources

Cooperative Brønsted Acid and Photo‐Promoted Stereoselective Synthesis of Substituted Piperidones

open access: yesAngewandte Chemie, EarlyView.
A Brønsted acid cooperates with a photoexcited carbonyl triplet to promote stereoselective C─C bond formation in disubstituted piperidones through a chromophore‐activator strategy. The Brønsted acid lowers the excitation energy gap, directs selective C─N bond cleavage over C─C fragmentation after H‐atom transfer, and enables enantioselective C─C bond ...
Qiupeng Peng   +5 more
wiley   +2 more sources

Autocrine regulation of human sperm motility by tachykinins

open access: yesReproductive Biology and Endocrinology, 2010
Background We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa.
Pinto Francisco M   +7 more
doaj   +1 more source

Opioid regulation of Mu receptor internalisation: relevance to the development of tolerance and dependence [PDF]

open access: yes, 2010
Internalisation of the mu opioid receptor from the surface of cells is generally achieved by receptor occupancy with agonist ligands of high efficacy. However, in many situations the potent analgesic morphine fails to promote internalisation effectively ...
Lopez-Gimenez, J.F., Milligan, G.
core   +2 more sources

Neurokinin receptor antagonists as potential non-hormonal treatments for vasomotor symptoms of menopause

open access: yesTherapeutic Advances in Reproductive Health, 2023
Vasomotor symptoms of menopause (VMS), otherwise known as hot flashes, can significantly impact women’s quality of life. Up to 87% of women report hot flashes during or after their menopause transition, and can last for a median duration of 7.4 years ...
Melissa Conklin, Nanette Santoro
doaj   +1 more source

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