Results 101 to 110 of about 26,034 (198)

Evaluación del uso de rituximab en la neuromielitis óptica

Neurología, 2015
Resumen: Introducción: La neuromielitis óptica es un trastorno autoinmune, inflamatorio y desmielinizante del sistema nervioso central que afecta a la médula espinal y al nervio óptico, de carácter recurrente.
M.J. Fernández-Megía, B. Casanova-Estruch, F. Pérez-Miralles, J. Ruiz-Ramos, C. Alcalá-Vicente, J.L. Poveda-Andrés   +5 more
doaj   +1 more source

Spinal anesthesia for cesarean delivery in a woman with neuromyelitis optica. [PDF]

, 2014
Neuromyelitis optica (NMO), or Devic's disease, is an idiopathic severe demyelinating disease that preferentially affects the optic nerve and spinal cord. Neuraxial anesthesia in women with multiple sclerosis is widely accepted, but reports of the use of
Ciliberto, C, Dinges, E, Greene, N, Landau, R, Sedensky, M   +4 more
core   +1 more source

Successful Treatment of Recurrent Painful Muscle Spasms After Total Hip Arthroplasty With Oxcarbazepine: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Painful muscle spasms are characterized by sudden onset of involuntary muscle contractions accompanying severe pain. The occurrence of painful muscle spasms after total hip arthroplasty (THA) is extremely rare in clinical practice. We report a case in which a patient developed painful muscle spasms after THA, and symptoms were controlled by ...
Youhan Yang, Wanqin Zheng, Yinxian Wen, Liaobin Chen   +3 more
wiley   +1 more source

A Rare Clinical Manifestation of Disseminated Tuberculosis: Case Report of Tuberculous Meningitis With Flaccid Paralysis

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case highlights a rare presentation of disseminated tuberculosis in a child, manifesting as tuberculous meningitis and flaccid paralysis due to spinal tuberculosis. Timely initiation of antitubercular therapy, corticosteroids, and ventriculoperitoneal shunt placement led to full recovery, emphasizing tuberculosis consideration in atypical
Aisha Haleem, Saad Ashraf, Areeba Ahsan, Maria Qadri, Iqra shahid, Biruk Demisse Ayalew   +5 more
wiley   +1 more source

Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome [PDF]

, 2016
Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG-IgG).
Asgari, Nasrin, Borisow, Nadja, Jarius, Sven, Kleiter, Ingo, Pache, Florence [u. v. m.], Pitarokoili, Kalliopi, Ruprecht, Klemens   +6 more
core   +1 more source

Elevated CHI3L1 as a Potential Biomarker of Cognitive Dysfunction in Anti‐NMDAR Encephalitis: Evidence From Clinical Results and Mice Model

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Astrocyte‐derived CHI3L1 is elevated in both a mouse model and pediatric patients with anti‐NMDAR encephalitis, coinciding with impaired hippocampal neurogenesis and cognitive deficits. CHI3L1 may serve as a potential biomarker for long‐term cognitive dysfunction in anti‐NMDAR encephalitis. ABSTRACT Background Anti‐N‐methyl‐D‐aspartate receptor (NMDAR)
Yuhang Li, Ran Ding, Jiaxin Yang, Xiaoyue Yang, Ziyao Han, Xue Li, Jie Liu, Yan Jiang, Li Cheng, Jiannan Ma, Hanyu Luo, Li Jiang   +11 more
wiley   +1 more source

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

Nano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini, Gillian D. Mahumane, Pradeep Kumar, Yahya E. Choonara   +3 more
wiley   +1 more source

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Asgari, Nasrin, Berg, Carsten Tue, Khorooshi, Reza, Mørch, Marlene Thorsen, Owens, Trevor   +4 more
core   +2 more sources

B Cell Differentiation Model for Identifying Predictors of Responses to Rituximab‐Mediated B Cell Depletion in Rheumatic Diseases

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Rituximab (RTX), an anti‐CD20 monoclonal antibody, has been used to treat autoimmune diseases such as rheumatoid arthritis (RA). However, variability in therapeutic response to RTX remains a challenge. Here, a systems model is developed to mimic B cell differentiation leading to antibody‐secreting cells (ASCs), including plasmablasts (PBs) and
Tomohisa Nakada, Donald E. Mager
wiley   +1 more source

Neuromyelitis optica (devic’s disease) in a 10 years old boy. [PDF]

, 2016
Neuromyelitis optica (NMO) also known as Devic’s disease is an acute demyelinating disorder combined with optic neuritis and transverse myelitis.A 10 years old boy presented in the ER with the complaints of fever and back pain for past 10 days and ...
Ibrahim, Shahnaz, Jan, Dr.Farida, Shabir, Amber   +2 more
core   +1 more source