Results 21 to 30 of about 2,828,690 (175)

Treatment of Neuromyelitis Optica Spectrum Disorders [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune central nervous system (CNS) inflammatory disorder that can lead to serious disability and mortality. Females are predominantly affected, including those within the reproductive age. Most patients develop relapsing attacks of optic neuritis; longitudinally extensive transverse myelitis ...
Chan, Koon-Ho, Lee, Chi-Yan
openaire   +2 more sources

Neuromyelitis Optica Spectrum Disorder

open access: yesCureus, 2023
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune condition characterized by recurrent episodes of optic neuritis (ON) and transverse myelitis. This case report aims to highlight the importance of considering atypical presentations of NMOSD when confronted with MRI-detected Wernicke's encephalopathy.
Cazzaniga, Juliana   +5 more
openaire   +2 more sources

Update on neuromyelitis optica spectrum disorder [PDF]

open access: yesCurrent Opinion in Ophthalmology, 2020
Purpose of reviewNeuromyelitis optica spectrum disorder is an autoimmune disease that causes optic neuritis and transverse myelitis. Attacks can cause severe neurological damage leading to blindness and paralysis. Understanding of the immunopathogenesis of this disease has led to major breakthroughs in diagnosis and treatment.
Kathryn B, Holroyd   +2 more
openaire   +2 more sources

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients [PDF]

open access: yes, 2012
BACKGROUND: The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so far about the clinical impact of
Jarius Sven   +269 more
core   +2 more sources

Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate [PDF]

open access: yesBMC Neurology, 2014
To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD).We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample
Ramanathan, Ramnath Santosh   +2 more
openaire   +2 more sources

Research progress of neuromyelitis optica spectrum disorders: Chinese scholars' reports published abroad

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2016
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of central nervous system (CNS), characterized by severe optic neuritis (ON) and transverse myelitis (TM). Since the discovery of NMO-immunoglobulin G (NMO-IgG), the definition of NMO
Jie-xi WEN   +3 more
doaj   +1 more source

Course of neuromyelitis optica during inadvertent pregnancy in a patient treated with rituximab [PDF]

open access: yes, 2009
In neuromyelitis optica (NMO), the monoclonal B-cell antibody rituximab is a therapeutic option. Little is known about the course of NMO and the safety of rituximab during pregnancy.
Hohlfeld, R.   +4 more
core   +1 more source

Neuromyelitis optica spectrum disorder: an overview [PDF]

open access: yesActa Neurobiologiae Experimentalis, 2020
Neuromyelitis optica also known as Devic's syndrome is a rare autoimmune disorder that predominantly targets the optic nerves and the spinal cord. It is a debilitating disorder that damages a person's health. Initially it was considered as a variant of multiple sclerosis (MS).
Ramakrishnan, Pooja   +1 more
openaire   +2 more sources

Volume of hippocampal subfields and cognitive deficits in neuromyelitis optica spectrum disorders

open access: yes, 2021
Aquaporin-4 (AQP4) water channel is involved in hippocampal plasticity and is the target of neuromyelitis optica spectrum disorders (NMOSD) autoimmunity.
Laura Cacciaguerra   +13 more
core   +1 more source

Status of the neuromyelitis optica spectrum disorder in Latin America

open access: yes, 2021
Background: Neuromyelitis optica spectrum disorders (NMOSD) is an increasing diagnostic and therapeutic challenge in Latin America (LATAM). Despite the heterogeneity of this population, ethnic and socioeconomic commonalities exist, and epidemiologic ...
Douglas Kazutoshi Sato   +88 more
core   +1 more source

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