Results 31 to 40 of about 12,119 (223)

Immunopathological Effects Of Aquaporin-4 Ig G In Neuromyelitis Optica Spectrum Disorders [PDF]

, 2017
published_or_final_versio
Chan, KH, Ng, CL, Yick, LW
core   +1 more source

Treatment of Neuromyelitis Optica Spectrum Disorders [PDF]

International Journal of Molecular Sciences, 2021
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune central nervous system (CNS) inflammatory disorder that can lead to serious disability and mortality. Females are predominantly affected, including those within the reproductive age. Most patients develop relapsing attacks of optic neuritis; longitudinally extensive transverse myelitis ...
Chan, Koon-Ho, Lee, Chi-Yan
openaire   +2 more sources

Neuromyelitis optica spectrum disorders in pediatric patients

Неврология, нейропсихиатрия, психосоматика, 2018
Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord.
Yu. V. Tokareva, A. S. Kotov, M. V. Panteleeva, M. S. Bunak   +3 more
doaj   +1 more source

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias, Asseyer, Susanna, Bellmann-Strobl, Judith, Hauser, Anja E., Koppen, Sofie van, Lindquist, Randall L., Mothes, Ronja, Niesner, Raluca A., Ostendorf, Lennard, Paul, Friedemann, Radbruch, Helena, Ruprecht, Klemens   +11 more
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Consensus of expert advices on routing, diagnosis, and management of patients with neuromyelitis optica spectrum disorders

Неврология, нейропсихиатрия, психосоматика, 2021
Neuromyelitis optica spectrum disorders (NMOSDs) are autoimmune inflammatory disorders accompanied by central nervous system damage, widespread immunemediated demyelination, and axonal damage, involving mainly the optic nerves, spinal cord, and area ...
A. N. Boyko, K. Z. Bakhtiyarova, L. V. Brylev, M. N. Zakharova, D. S. Kasatkin, D. S. Korobko, S. V. Kotov, V. S. Krasnov, N. A. Malkova, E. V. Popova, S. A. Sivertseva, T. O. Simaniv, A. A. Sokolova, N. A. Totolyan, T. N. Trushnikova, F. A. Khabirov, N. V. Khachanova   +16 more
doaj   +1 more source

The Gut Microbiome in Neuromyelitis Optica. [PDF]

, 2017
Neuromyelitis optica (NMO) is a rare, disabling, sometimes fatal central nervous system inflammatory demyelinating disease that is associated with antibodies ("NMO IgG") that target the water channel protein aquaporin-4 (AQP4) expressed on astrocytes ...
Baranzini, Sergio E, Cree, Bruce AC, Spencer, Collin M, Zamvil, Scott S   +3 more
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Double-negative neuromyelitis optica spectrum disorder

Multiple Sclerosis Journal, 2023
Most patients with neuromyelitis optica spectrum disorders (NMOSD) test positive for aquaporin-4 antibody (AQP4-IgG) or myelin oligodendrocyte glycoprotein antibodies (MOG-IgG). Those who are negative are termed double-negative (DN) NMOSD and may constitute a diagnostic and therapeutic challenge.
Yan Wu, Ruth Geraldes, Maciej Juryńczyk, Jacqueline Palace   +3 more
openaire   +2 more sources

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders: progress of experimental models based on disease pathogenesis

Neural Regeneration Research
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction. To date, no effective treatment exists as the exact causative mechanism remains unknown.
Li Xu, Huiming Xu, Changyong Tang
doaj   +1 more source

Late Onset of Neuromyelitis Optica Spectrum Disorders

Neurology and Therapy, 2019
Introduction Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system. NMOSD starting after the age of 50 years is considered a “late onset” (LO-NMOSD) and seems to be particularly aggressive ...
Yara Dadalti Fragoso, Heloisa Helena Ruocco, Ronaldo Maciel Dias, Hideraldo Cabeça, Ricardo Gonçalves, Nise A. de Carvalho Sousa, Caroline Vieira Spessotto, Carlos Bernardo Tauil, Soniza Vieira Alves-Leon, Sidney Gomes, Marcus Vinicius M. Gonçalves, Suzana C. Nunes Machado, Andrea Anacleto, Eber Castro Correa, Maria Lucia V. Pimentel, Gutemberg Augusto C. Santos   +15 more
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Neuromyelitis optic spectrum disorders (NMOSD): from pathogenesis to targeted therapy

Неврология, нейропсихиатрия, психосоматика, 2023
In the review, we present the main pathogenetic mechanisms of the development of neuromyelitis optic spectrum disorders (NMOSD) associated with the appearance of anti-aquaporin-4 (APQ4-IgG) autoantibodies: damage to astrocytes, including complement ...
P. A. Zaitseva, A. N. Boyko
doaj   +1 more source