Results 41 to 50 of about 12,119 (223)
Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder [PDF]
, 2016 Background: Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are autoimmune demyelinating diseases distinguished clinically by selective involvement in NMOSD of optic nerves and spinal cord. Early clinical manifestations are
Evans, David R. S. +6 more
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Recent developments in MOG-IgG associated neurological disorders
Therapeutic Advances in Neurological Disorders, 2020 In the past few years, acquired demyelinating syndromes of the central nervous system associated with antibodies against myelin oligodendrocyte glycoprotein (MOG) have evolved into a new inflammatory disease entity distinct from neuromyelitis optica ...
Harald Hegen, Markus Reindl
doaj +1 more source
The history of neuromyelitis optica [PDF]
, 2013 The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO).
Jarius, Sven, Wildemann, Brigitte
core +1 more source
Update on neuromyelitis optica spectrum disorder [PDF]
Current Opinion in Ophthalmology, 2020 Purpose of reviewNeuromyelitis optica spectrum disorder is an autoimmune disease that causes optic neuritis and transverse myelitis. Attacks can cause severe neurological damage leading to blindness and paralysis. Understanding of the immunopathogenesis of this disease has led to major breakthroughs in diagnosis and treatment.
Kathryn B, Holroyd +2 more
openaire +2 more sources
Neuromyelitis Optica Spectrum Disorders (NMOSD); Diagnostic criteria (ORP-56) [PDF]
Neurology Letters, 2023 Neuromyelitis optica spectrum disorders (NMOSD) is an autoimmune astrocytopathy. The term NMOSD is used as an umbrella term that refers to Aquaporin-4 (IgG) positive NMO and some closely related clinical syndromes without AQP4-IgG. Core clinical features
Maryam Poursadeghfard
doaj
Research progress of neuroregeneration in neuromyelitis optica spectrum disorders
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 In the treatment of neurological diseases, neuroregeneration is a contentious and challenging issue. Our understanding of the mechanisms related to neuroregeneration in neuromyelitis optica spectrum disorders (NMOSDs) is currently restricted and there ...
QIU Wei , LUO Wen⁃jing
doaj +1 more source
direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate [PDF]
, 2014 Background Neuromyelitis optica (NMO, Devic syndrome) is associated with antibodies to aquaporin-4 (NMO-IgG/AQP4-Ab) in the majority of cases. NMO- IgG/AQP4-Ab seropositivity in patients with NMO and its spectrum disorders has important differential ...
Aktas. Orhan +9 more
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Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate [PDF]
BMC Neurology, 2014 To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD).We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample
Ramanathan, Ramnath Santosh +2 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
The profile of patients followed at the Neuroimmunology Clinic at UNIFESP: 20 years analysis [PDF]
, 2015 Objective: To describe the clinical activities at the Neuroimmunology Clinic of the Universidade Federal de São Paulo (UNIFESP) from 1994 to 2013. Method: the final diagnosis of all patients that attended the center was reviewed and established upon ...
Bichuetti, Denis Bernardi +8 more
core +2 more sources