Results 41 to 50 of about 2,828,690 (175)

Symptomatic and restorative therapies in neuromyelitis optica spectrum disorders [PDF]

, 2021
Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory conditions that primarily target the optic nerves, spinal cord, brainstem, and occasionally the cerebrum. NMOSD is characterized by recurrent attacks of visual, motor,
Salazar-Camelo, Andrea, Broadley, Simon, Abboud, Hesham, Alroughani, Raed, Goodman, Andrew, Matiello, Marcelo, Mealy, Maureen A, Paolilo, Renata Barbosa, Planchon, Sarah M, Bennett, Jeffrey, Asgari, Nasrin, George, Naveen, Altintas, Ayse, Apiwattanakul, Metha, et al., Kazuo Fujihara, Jeffrey Bennett, Sarah M. Planchon, Celia Oreja-Guevara, Pablo Villoslada, Edgar Carnero Contentti, Renata Barbosa Paolilo, Chao Quan, Esther Melamed, Ayse Altintas, Anne-Katrin Pröbstel, Youssoufa Maiga, Jacqueline Palace, Simon Broadley, Ilya Kister, Andrew Goodman, Raed Alroughani, Jyh Yung Hor, Bassem Yamout, Terrence F. Blaschke, Yang Mao-Draayer, Ingo Kleiter, Andrea Salazar-Camelo, Dorlan Kimbrough, Jose Flores-Rivera, null null, Jeffrey A. Cohen, Dean Wingerchuk, Marcelo Matiello, Nasrin Asgari, Saif Huda, Ibis Soto de Castillo, Maureen A. Mealy, Denis Bernardi Bichuetti, Silvia Tenembaum, Naveen George, Sasitorn Siritho, Hesham Abboud, Guillermo Delgado-Garcia, Kerstin Hellwig, Raffaele Iorio, Marco Lana-Peixoto, Maria Jose Sa, Sara Mariotto, Joachim Havla, Metha Apiwattanakul, Alexey Boyko, Michael Levy, Irena Dujmovic Basuroski, Najib Kissani, Peiqing Qian, Claire Riley, Maria Isabel Leite, Jens Wuerfel, Marius Ringelstein, Veronika E. Neubrand, Sven Jarius, Terry J. Smith, Michael Yeaman   +73 more
core   +1 more source

Research progress of neuroregeneration in neuromyelitis optica spectrum disorders

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
In the treatment of neurological diseases, neuroregeneration is a contentious and challenging issue. Our understanding of the mechanisms related to neuroregeneration in neuromyelitis optica spectrum disorders (NMOSDs) is currently restricted and there ...
QIU Wei , LUO Wen⁃jing
doaj   +1 more source

Frequency of non optico-spinal manifestation in neuromyelitis optica spectrum disorder at tertiary care hospital in Pakistan

Journal of the Pakistan Medical Association
Objective: To determine the frequency of non-optico-spinal manifestations in neuromyelitis optica spectrum disorder patients in a tertiary care setting.
Rashna, Sumera Rafat Umer, Wajid Jawaid, Qamar un Nisa, Tahreem Sajjad, Minna Ahmed   +5 more
doaj   +1 more source

Neuromyelitis Optica Spectrum Disorders (NMOSD); Diagnostic criteria (ORP-56) [PDF]

Neurology Letters, 2023
Neuromyelitis optica spectrum disorders (NMOSD) is an autoimmune astrocytopathy. The term NMOSD is used as an umbrella term that refers to Aquaporin-4 (IgG) positive NMO and some closely related clinical syndromes without AQP4-IgG. Core clinical features
Maryam Poursadeghfard
doaj  

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Neuromyelitis optica spectrum disorder

Brain and nerve = Shinkei kenkyu no shinpo, 2021
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder primarily associated with optic neuritis, myelitis or area postrema syndrome. Several lines of evidence suggest that NMOSD is a humoral immune disease mainly caused by aquaporin-4 antibody and related complement-dependent cytotoxicity against astrocytes.
openaire   +3 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

The efficacy of rituximab in patients with neuromyelitis optica spectrum disorder: A real-world study from Turkey

, 2021
Background Neuromyelitis optica spectrum disorders (NMOSD) are a group of antibody-mediated chronic inflammatory diseases of the central nervous system.
Aksel Siva, Mesude Tütüncü, Murat Kürtüncü, TERZİ, MURAT, GÜMÜŞ, HALUK, Sen, Sedat, Siva, Aksel, Tutuncu, Mesude, Murat Terzi, Cihat Uzunköprü, Uğur Uygunoğlu, ÖZAKBAŞ, SERKAN, Uygunoglu, Ugur, Tutuncu, Melih, BECKMANN, YEŞİM, Rıfat Erdem Toğrol, Gunduz, Tuncay, Melih Tütüncü, Demir, Serkan, Togrol, Rifat Erdem, Yeşim Beckmann, Kurtuncu, Murat, Bilge Piri Çınar, Tuncay Gündüz, Haluk Gümüş, Serkan Demir, TÜRE, HATİCE SABİHA, Serkan Özakbaş, Hatice Sabiha Türe, Uzunkopru, Cihat, ÇİNAR, BİLGE PİRİ, Sedat Şen   +31 more
core   +1 more source

Differential diagnosis of neuromyelitis optica spectrum disorders

Therapeutic Advances in Neurological Disorders, 2017
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central nervous system (CNS) mostly manifesting as optic neuritis and/or myelitis, which are frequently recurrent/bilateral or longitudinally extensive, respectively.
Sung-Min Kim, Seong-Joon Kim, Haeng Jin Lee, Hiroshi Kuroda, Jacqueline Palace, Kazuo Fujihara   +5 more
doaj   +1 more source