Results 11 to 20 of about 465,559 (289)

Melatonin: Facts, Extrapolations and Clinical Trials

Biomolecules, 2023
Melatonin is a fascinating molecule that has captured the imagination of many scientists since its discovery in 1958. In recent times, the focus has changed from investigating its natural role as a transducer of biological time for physiological systems ...
J. A. Boutin, D. J. Kennaway, R. Jockers
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Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Frontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki, Amira Namsi, Amira Namsi, Yosra Hamdi, Seyma Bahdoudi, Seyma Bahdoudi, Ikram Ghouili, Julien Chuquet, Jérôme Leprince, Jérôme Leprince, Benjamin Lefranc, Benjamin Lefranc, Taoufik Ghrairi, Marie-Christine Tonon, Gérard Lizard, David Vaudry, David Vaudry   +16 more
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Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]

, 2018
Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria, Martellucci, Stefano, Mattei, Vincenzo, Piccoli, Luca, Santacroce, Costantino, Santilli, Francesca, Sorice, Maurizio   +6 more
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APP Expression in Primary Neuronal Cell Cultures fromP6 Mice during in vitro Differentiation [PDF]

, 1993
Primary neuronal cell cultures from P6 mice were investigated in order to study amyloid protein precursor (APP) gene expression in differentiating neurons.
Beyreuther, K., Dichgans, Martin, König, G., Masters, C. L., Mönning, U., Sandbrink, R.   +5 more
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Differentiating lower motor neuron syndromes [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2016
Lower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and may arise from pathology affecting the distal motor nerve up to the level of the anterior horn cell. A variety of hereditary causes are recognised, including spinal muscular atrophy, distal hereditary motor neuropathy and LMN variants of familial motor neuron ...
Garg, N, Park, SB, Vucic, S, Yiannikas, C, Spies, J, Howells, J, Huynh, W, Matamala, JM, Krishnan, AV, Pollard, JD, Cornblath, DR, Reilly, MM, Kiernan, MC   +12 more
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Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

Frontiers in Endocrinology, 2019
Granins and their derived-peptides are useful markers of secretion from normal and tumoral neuroendocrine cells. The need to identify new diagnostic markers for neuroendocrine tumors, including pituitary tumors prompted us to determine plasma levels of ...
Johann Guillemot, Marlène Guérin, Anne-Françoise Cailleux, Antoine-Guy Lopez, Jean-Marc Kuhn, Youssef Anouar, Laurent Yon   +6 more
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Modeling the functional genomics of autism using human neurons. [PDF]

, 2012
Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation,
Chen, L, Gao, F, Gao, K, Geschwind, DH, Konopka, G, Lowe, JK, Lu, D, Mukamel, Z, Osborn, GE, Rosen, E, Wexler, E   +10 more
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Nrf2 promotes neuronal cell differentiation [PDF]

Free Radical Biology and Medicine, 2009
The transcription factor Nrf2 has emerged as a master regulator of the endogenous antioxidant response, which is critical in defending cells against environmental insults and in maintaining intracellular redox balance. However, whether Nrf2 has any role in neuronal cell differentiation is largely unknown. In this report, we have examined the effects of
Fei, Zhao, Tongde, Wu, Alexandria, Lau, Tao, Jiang, Zheping, Huang, Xiao-Jun, Wang, Weimin, Chen, Pak Kin, Wong, Donna D, Zhang   +8 more
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The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

Endocrine Connections, 2019
Objective: Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity.
Gaëtan Prévost, Marie Picot, Marie-Anne Le Solliec, Arnaud Arabo, Hind Berrahmoune, Mouna El Mehdi, Saloua Cherifi, Alexandre Benani, Emmanuelle Nédélec, Françoise Gobet, Valéry Brunel, Jérôme Leprince, Hervé Lefebvre, Youssef Anouar, Nicolas Chartrel   +14 more
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Eel Kisspeptins: Identification, Functional Activity, and Inhibition on both Pituitary LH and GnRH Receptor Expression

Frontiers in Endocrinology, 2018
The European eel (Anguilla anguilla) presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins.
Jérémy Pasquier, Anne-Gaëlle Lafont, Florian Denis, Benjamin Lefranc, Christophe Dubessy, Antonio Moreno-Herrera, Antonio Moreno-Herrera, Hubert Vaudry, Jérôme Leprince, Sylvie Dufour, Karine Rousseau   +10 more
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