Results 11 to 20 of about 270,002 (292)

Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases

open access: yesBiomolecules, 2021
Biomolecules has launched a Special Issue entitled “Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases [...]
Philippe De Deurwaerdère   +1 more
doaj   +1 more source

Melatonin: Facts, Extrapolations and Clinical Trials

open access: yesBiomolecules, 2023
Melatonin is a fascinating molecule that has captured the imagination of many scientists since its discovery in 1958. In recent times, the focus has changed from investigating its natural role as a transducer of biological time for physiological systems ...
J. A. Boutin, D. J. Kennaway, R. Jockers
doaj   +1 more source

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

open access: yesFrontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki   +16 more
doaj   +1 more source

Differentiating lower motor neuron syndromes [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2016
Lower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and may arise from pathology affecting the distal motor nerve up to the level of the anterior horn cell. A variety of hereditary causes are recognised, including spinal muscular atrophy, distal hereditary motor neuropathy and LMN variants of familial motor neuron ...
Garg, N   +12 more
openaire   +3 more sources

Characterization of the EM66 Biomarker in the Pituitary and Plasma of Healthy Subjects With Different Gonadotroph Status and Patients With Gonadotroph Tumor

open access: yesFrontiers in Endocrinology, 2019
Granins and their derived-peptides are useful markers of secretion from normal and tumoral neuroendocrine cells. The need to identify new diagnostic markers for neuroendocrine tumors, including pituitary tumors prompted us to determine plasma levels of ...
Johann Guillemot   +6 more
doaj   +1 more source

Nrf2 promotes neuronal cell differentiation [PDF]

open access: yesFree Radical Biology and Medicine, 2009
The transcription factor Nrf2 has emerged as a master regulator of the endogenous antioxidant response, which is critical in defending cells against environmental insults and in maintaining intracellular redox balance. However, whether Nrf2 has any role in neuronal cell differentiation is largely unknown. In this report, we have examined the effects of
Fei, Zhao   +8 more
openaire   +2 more sources

The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

open access: yesEndocrine Connections, 2019
Objective: Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity.
Gaëtan Prévost   +14 more
doaj   +1 more source

Eel Kisspeptins: Identification, Functional Activity, and Inhibition on both Pituitary LH and GnRH Receptor Expression

open access: yesFrontiers in Endocrinology, 2018
The European eel (Anguilla anguilla) presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins.
Jérémy Pasquier   +10 more
doaj   +1 more source

Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Against Cognitive Decline in Neurodegenerative Diseases

open access: yesFrontiers in Cellular Neuroscience, 2020
Cognitive impairment is one of the major symptoms in most neurodegenerative disorders such as Alzheimer’s (AD), Parkinson (PD), and Huntington diseases (HD), affecting millions of people worldwide.
Irene Solés-Tarrés   +3 more
doaj   +1 more source

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