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The Histone Modifications of Neuronal Plasticity. [PDF]
Neural Plast, 2021 Nucleosomes composed of histone octamer and DNA are the basic structural unit in the eukaryote chromosome. Under the stimulation of various factors, histones will undergo posttranslational modifications such as methylation, phosphorylation, acetylation ...
Geng H, Chen H, Wang H, Wang L.
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Cathepsins in neuronal plasticity.
Neural Regen Res, 2021 Proteases comprise a variety of enzymes defined by their ability to catalytically hydrolyze the peptide bonds of other proteins, resulting in protein lysis.
Tran AP, Silver J.
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Autophagy in Neuronal Development and Plasticity [PDF]
Trends in Neurosciences, 2020 Autophagy is a highly conserved intracellular clearance pathway in which cytoplasmic contents are trafficked to the lysosome for degradation. Within neurons, it helps to remove damaged organelles and misfolded or aggregated proteins and has therefore been the subject of intense research in relation to neurodegenerative disease.
Angeleen Fleming, D. Rubinsztein
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Oligodendrocytes and myelin limit neuronal plasticity in visual cortex. [PDF]
NatureDevelopmental myelination is a protracted process in the mammalian brain1. One theory for why oligodendrocytes mature so slowly posits that myelination may stabilize neuronal circuits and temper neuronal plasticity as animals age2–4.
Xin W +7 more
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Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. [PDF]
Mol Neurodegener, 2022 Background Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer’s disease (AD) and is considered to result from neurodegeneration.
Visser PJ +29 more
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Plasticity of intrinsic neuronal excitability [PDF]
Current Opinion in Neurobiology, 2019 Long-term synaptic modification is not the exclusive mode of memory storage, and persistent regulation of voltage-gated ion channels also participates in memory formation. Intrinsic plasticity is expressed in virtually all neuronal types including principal cells and interneurons.
D. Debanne +2 more
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Neuronal Plasticity in the Entorhinal Cortex
Neural Plasticity, 2008 The entorhinal cortex (EC) is a unique and fascinating structure, constituting a highly parallel interface between phylogenetically old cortex (hippocampus) and higher neocortical areas. The literature related to the EC has increased dramatically in the past 30 years. A simple PubMed search for EC lists around 20–40 articles per year in the early 1980s.
C. Andrew Chapman +2 more
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Astrocyte and Neuronal Plasticity in the Somatosensory System [PDF]
Neural Plasticity, 2015 Changing the whisker complement on a rodent's snout can lead to two forms of experience-dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are somatotopically represented.
Robert E. Sims +3 more
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Science Advances, 2022 The comorbidity of chronic pain and mental dysfunctions such as depression and anxiety disorders has long been recognized, but the underlying mechanisms remain poorly understood.
Naoki Yamauchi +7 more
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S‐nitrosation and neuronal plasticity [PDF]
British Journal of Pharmacology, 2014 Nitric oxide (NO) has long been recognized as a multifaceted participant in brain physiology. Despite the knowledge that was gathered over many years regarding the contribution of NO to neuronal plasticity, for example the ability of the brain to change in response to new stimuli, only in recent years have we begun to understand how NO acts on the ...
Inês M. Araújo +3 more
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