Results 1 to 10 of about 349,501 (328)

Cathepsins in neuronal plasticity.

Neural Regen Res, 2021
Proteases comprise a variety of enzymes defined by their ability to catalytically hydrolyze the peptide bonds of other proteins, resulting in protein lysis. Cathepsins, specifically, encompass a class of at least twenty proteases with potent endopeptidase activity.
Tran AP, Silver J.
europepmc   +4 more sources

The role of neuronal plasticity in cervical spondylotic myelopathy surgery: functional assessment and prognostic implication. [PDF]

Neurosurg Rev, 2023
Bonosi L, Musso S, Cusimano LM, Porzio M, Giovannini EA, Benigno UE, Giammalva GR, Gerardi RM, Brunasso L, Costanzo R, Paolini F, Sciortino A, Campisi BM, Giardina K, Scalia G, Iacopino DG, Maugeri R.   +16 more
europepmc   +3 more sources

Neuronal plasticity and its role in Alzheimer's disease and Parkinson's disease. [PDF]

Neural Regen Res
Jahan I, Harun-Ur-Rashid M, Islam MA, Sharmin F, Al Jaouni SK, Kaki AM, Selim S.   +6 more
europepmc   +2 more sources

ß‐Hydroxy ß‐methyl butyrate, a muscle‐building supplement, restores neuronal plasticity in Alzheimer’s disease model [PDF]

Alzheimers Dement
Paidi R, Pahan K.
europepmc   +3 more sources

Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice

Translational Psychiatry, 2021
Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz, Vivian A. Schöttle, Paulina Nemcova, Florian P. Binder, Tim Ebert, Katharina Domschke, Carsten T. Wotjak   +6 more
doaj   +1 more source

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma

Pharmaceutics, 2022
Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which neuroinflammation and glial cells play an important role in exerting a functional immune and damage-
Ana Belen Lopez-Rodriguez, Céline Decouty-Perez, Victor Farré-Alins, Alejandra Palomino-Antolín, Paloma Narros-Fernández, Javier Egea   +5 more
doaj   +1 more source

Lobe X of the Cerebellum: A Natural Neuro-Resistant Region

Anatomia, 2023
The cerebellum is an encephalic region classically known for its central role in the control of movement, although recent research has revealed its involvement in other cognitive and affective tasks. Several different pathologies are known to affect this
Carlos Hernández-Pérez, Eduardo Weruaga, David Díaz   +2 more
doaj   +1 more source

Intranasal Administration of PACAP Is an Efficient Delivery Route to Reduce Infarct Volume and Promote Functional Recovery After Transient and Permanent Middle Cerebral Artery Occlusion

Frontiers in Endocrinology, 2021
Intranasal (IN) administration appears to be a suitable route for clinical use as it allows direct delivery of bioactive molecules to the central nervous system, reducing systemic exposure and sides effects.
Asma Cherait, Asma Cherait, Asma Cherait, Julie Maucotel, Julie Maucotel, Benjamin Lefranc, Benjamin Lefranc, Jérôme Leprince, Jérôme Leprince, David Vaudry, David Vaudry   +10 more
doaj   +1 more source

Secretagogin expression in the mouse olfactory bulb under sensory impairments

Scientific Reports, 2020
The interneurons of the olfactory bulb (OB) are characterized by the expression of different calcium-binding proteins, whose specific functions are not fully understood.
L. Pérez-Revuelta, P. G. Téllez de Meneses, M. López, J. G. Briñón, E. Weruaga, D. Díaz, J. R. Alonso   +6 more
doaj   +1 more source

Whole-brain tracking of cocaine and sugar rewards processing

Translational Psychiatry, 2023
Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch, Joanna Klos, Monika Pawłowska, Justyna Wiśniewska, Diana Legutko, Urszula Szachowicz, Leszek Kaczmarek, Anna Beroun   +7 more
doaj   +1 more source