Results 91 to 100 of about 1,018,658 (375)
Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]
, 2014 Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun +3 more
core +1 more source
Palatable Hyper-Caloric Foods Impact on Neuronal Plasticity
Frontiers in Behavioral Neuroscience, 2017 Neural plasticity is an intrinsic and essential characteristic of the nervous system that allows animals “self-tuning” to adapt to their environment over their lifetime.
Jean-Pascal Morín +6 more
semanticscholar +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Cell Transplantation, 2012 Bone marrow-derived cells have different plastic properties, especially regarding cell fusion, which increases with time and is prompted by tissue injury.
David Díaz +3 more
doaj +1 more source
Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome
Frontiers in Molecular Neuroscience, 2023 Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized molecular phenotypes of Fmr1 KO mice, a model of FXS, is increased translation of synaptic proteins ...
Magdalena Chojnacka +7 more
doaj +1 more source
MiRNAs in Astrocyte-Derived Exosomes as Possible Mediators of Neuronal Plasticity
Journal of Experimental Neuroscience, 2016 Astrocytes use gliotransmitters to modulate neuronal function and plasticity. However, the role of small extracellular vesicles, called exosomes, in astrocyte-to-neuron signaling is mostly unknown.
C. Lafourcade +4 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Stroke is a leading cause of long‐term disability in adults, with upper limb hemiparesis being a common impairment. Traditional training is mostly aimed at paralyzed limbs, but the effect of bilateral training is still unclear.
Fangfang Qian +7 more
wiley +1 more source
Cellular excitability and the regulation of functional neuronal identity: from gene expression to neuromodulation [PDF]
, 2006 The intrinsic properties of a neuron determine the translation of synaptic input to axonal output. It is this input– output relationship that is the heart of all nervous system activity.
Baines, Richard A. +5 more
core +2 more sources
Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration
Journal of Neural Transplantation and Plasticity, 2016 Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central nervous system, ranging from the regulation of gene transcription, cellular signaling, modulation of synaptic structure, and transmission and glial function to ...
S. Vyas +6 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source