Results 21 to 30 of about 1,018,658 (375)

Phosphatidylcholine restores neuronal plasticity of neural stem cells under inflammatory stress

open access: yesScientific Reports, 2021
The balances between NSCs growth and differentiation, and between glial and neuronal differentiation play a key role in brain regeneration after any pathological conditions.
Dario Magaquian   +3 more
semanticscholar   +1 more source

Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice

open access: yesTranslational Psychiatry, 2021
Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz   +6 more
doaj   +1 more source

GPCR voltage dependence controls neuronal plasticity and behavior

open access: yesNature Communications, 2021
G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions. Almost 20 years ago, GPCR activity was shown to be regulated by membrane potential in vitro, but whether the voltage dependence of GPCRs contributes to neuronal coding ...
Eyal Rozenfeld   +3 more
semanticscholar   +1 more source

Neuronal-Plasticity and Reward-Propagation Improved Recurrent Spiking Neural Networks

open access: yesFrontiers in Neuroscience, 2021
Different types of dynamics and plasticity principles found through natural neural networks have been well-applied on Spiking neural networks (SNNs) because of their biologically-plausible efficient and robust computations compared to their counterpart ...
Shuncheng Jia   +4 more
semanticscholar   +1 more source

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma

open access: yesPharmaceutics, 2022
Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which neuroinflammation and glial cells play an important role in exerting a functional immune and damage-
Ana Belen Lopez-Rodriguez   +5 more
doaj   +1 more source

Lobe X of the Cerebellum: A Natural Neuro-Resistant Region

open access: yesAnatomia, 2023
The cerebellum is an encephalic region classically known for its central role in the control of movement, although recent research has revealed its involvement in other cognitive and affective tasks. Several different pathologies are known to affect this
Carlos Hernández-Pérez   +2 more
doaj   +1 more source

Intranasal Administration of PACAP Is an Efficient Delivery Route to Reduce Infarct Volume and Promote Functional Recovery After Transient and Permanent Middle Cerebral Artery Occlusion

open access: yesFrontiers in Endocrinology, 2021
Intranasal (IN) administration appears to be a suitable route for clinical use as it allows direct delivery of bioactive molecules to the central nervous system, reducing systemic exposure and sides effects.
Asma Cherait   +10 more
doaj   +1 more source

Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

open access: yesNature Communications, 2020
Brain organoids are promising tools for disease modeling and drug development. For proper neuronal network formation excitatory and inhibitory neurons as well as glia need to co-develop.
M. Zafeiriou   +8 more
semanticscholar   +1 more source

Secretagogin expression in the mouse olfactory bulb under sensory impairments

open access: yesScientific Reports, 2020
The interneurons of the olfactory bulb (OB) are characterized by the expression of different calcium-binding proteins, whose specific functions are not fully understood.
L. Pérez-Revuelta   +6 more
doaj   +1 more source

Whole-brain tracking of cocaine and sugar rewards processing

open access: yesTranslational Psychiatry, 2023
Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch   +7 more
doaj   +1 more source

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