Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation. [PDF]
, 2019 Memory and learning involve activity-driven expression of proteins and cytoskeletal reorganization at new synapses, requiring posttranscriptional regulation of localized mRNA a long distance from corresponding nuclei.
Davis, Ilan +6 more
core +4 more sources
Network self-organization explains the statistics and dynamics of synaptic connection strengths in cortex [PDF]
, 2013 The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function.
Dimitrakakis, Christos +2 more
core +3 more sources
A geographically distributed bio-hybrid neural network with memristive plasticity [PDF]
, 2017 Throughout evolution the brain has mastered the art of processing real-world inputs through networks of interlinked spiking neurons. Synapses have emerged as key elements that, owing to their plasticity, are merging neuron-to-neuron signalling with ...
Corna, Andrea +10 more
core +1 more source
Epigenetic mechanisms of major depression: Targeting neuronal plasticity
Psychiatry and Clinical Neurosciences, 2018 Major depressive disorder is one of the most common mental illnesses as it affects more than 350 million people globally. Major depressive disorder is etiologically complex and disabling.
S. Uchida +3 more
semanticscholar +1 more source
Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network
Nature, 2020 Behavioural experiences activate the FOS transcription factor in sparse populations of neurons that are critical for encoding and recalling specific events1–3.
Ee-Lynn Yap +12 more
semanticscholar +1 more source
Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity
Journal of Neuroscience, 2018 In the adult brain, the extracellular matrix (ECM) influences recovery after injury, susceptibility to mental disorders, and is in general a strong regulator of neuronal plasticity.
D. Rowlands +8 more
semanticscholar +1 more source
The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]
, 2017 One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A. +32 more
core +2 more sources
Relation between gamma oscillations and neuronal plasticity in the visual cortex
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Learning is thought to be mediated by activity-dependent modification of neuronal interactions. To avoid maladaptive modifications of synaptic transmission by spurious activity, synaptic plasticity has to be gated.
R. Galuske, M. Munk, W. Singer
semanticscholar +1 more source
Alterations in brain connectivity due to plasticity and synaptic delay
, 2017 Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M. +8 more
core +1 more source
GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration
Journal of Neural Transplantation and Plasticity, 2019 In neurons, Glycogen Synthase Kinase-3β (GSK-3β) has been shown to regulate various critical processes underlying structural and functional synaptic plasticity.
T. Jaworski +2 more
semanticscholar +1 more source