Results 21 to 30 of about 188,649 (338)

Astrocyte control bursting mode of spiking neuron network with memristor-implemented plasticity [PDF]

open access: yes, 2023
A mathematical model of a spiking neuron network accompanied by astrocytes is considered. The network is composed of excitatory and inhibitory neurons with synaptic connections supplied by a memristor-based model of plasticity. Another mechanism for changing the synaptic connections involves astrocytic regulations using the concept of tripartite ...
arxiv   +1 more source

Event-driven simulations of a plastic, spiking neural network [PDF]

open access: yesPhys. Rev. E 84, 031908 (2011), 2011
We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing randomly with the same mean frequency.
arxiv   +1 more source

Critical neural networks with short and long term plasticity [PDF]

open access: yesPhys. Rev. E 97, 032312 (2018), 2017
In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems. It has been shown that dynamical synapses, as a form of short-term plasticity, can cause critical neuronal dynamics.
arxiv   +1 more source

Olfactory bulb plasticity ensures proper olfaction after severe impairment in postnatal neurogenesis

open access: yesScientific Reports, 2017
The olfactory bulb (OB) neurons establish a complex network that ensures the correct processing of the olfactory inputs. Moreover, the OB presents a lifelong addition of new neurons into its existing circuitry.
D. Díaz   +5 more
doaj   +1 more source

Birdsongs alleviate anxiety and paranoia in healthy participants

open access: yesScientific Reports, 2022
The present study investigated the effect of urban (traffic noise) vs. natural (birdsongs) soundscapes on mood, state paranoia, and cognitive performance, hypothesizing that birdsongs lead to significant improvements in these outcomes. An additional goal
E. Stobbe   +3 more
doaj   +1 more source

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

open access: yesAntioxidants, 2020
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins   +13 more
doaj   +1 more source

Evaluating the extent to which homeostatic plasticity learns to compute prediction errors in unstructured neuronal networks [PDF]

open access: yesarXiv, 2022
The brain is believed to operate in part by making predictions about sensory stimuli and encoding deviations from these predictions in the activity of "prediction error neurons." This principle defines the widely influential theory of predictive coding.
arxiv  

Neuronal plasticity and antidepressant actions [PDF]

open access: yesTrends in Neurosciences, 2013
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
René Hen, Eero Castrén
openaire   +3 more sources

Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila

open access: yesBio-Protocol, 2019
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter   +8 more
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington’s Disease Models: Role of PAC1 Receptor

open access: yesFrontiers in Pharmacology, 2022
Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés   +11 more
doaj   +1 more source

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