Astrocyte control bursting mode of spiking neuron network with memristor-implemented plasticity [PDF]
A mathematical model of a spiking neuron network accompanied by astrocytes is considered. The network is composed of excitatory and inhibitory neurons with synaptic connections supplied by a memristor-based model of plasticity. Another mechanism for changing the synaptic connections involves astrocytic regulations using the concept of tripartite ...
arxiv +1 more source
Event-driven simulations of a plastic, spiking neural network [PDF]
We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing randomly with the same mean frequency.
arxiv +1 more source
Critical neural networks with short and long term plasticity [PDF]
In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems. It has been shown that dynamical synapses, as a form of short-term plasticity, can cause critical neuronal dynamics.
arxiv +1 more source
Olfactory bulb plasticity ensures proper olfaction after severe impairment in postnatal neurogenesis
The olfactory bulb (OB) neurons establish a complex network that ensures the correct processing of the olfactory inputs. Moreover, the OB presents a lifelong addition of new neurons into its existing circuitry.
D. Díaz+5 more
doaj +1 more source
Birdsongs alleviate anxiety and paranoia in healthy participants
The present study investigated the effect of urban (traffic noise) vs. natural (birdsongs) soundscapes on mood, state paranoia, and cognitive performance, hypothesizing that birdsongs lead to significant improvements in these outcomes. An additional goal
E. Stobbe+3 more
doaj +1 more source
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins+13 more
doaj +1 more source
Evaluating the extent to which homeostatic plasticity learns to compute prediction errors in unstructured neuronal networks [PDF]
The brain is believed to operate in part by making predictions about sensory stimuli and encoding deviations from these predictions in the activity of "prediction error neurons." This principle defines the widely influential theory of predictive coding.
arxiv
Neuronal plasticity and antidepressant actions [PDF]
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
René Hen, Eero Castrén
openaire +3 more sources
Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter+8 more
doaj +1 more source
Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés+11 more
doaj +1 more source