Results 31 to 40 of about 345,454 (237)

Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila

open access: yesBio-Protocol, 2019
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter   +8 more
doaj   +1 more source

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

open access: yesAntioxidants, 2020
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins   +13 more
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington’s Disease Models: Role of PAC1 Receptor

open access: yesFrontiers in Pharmacology, 2022
Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés   +11 more
doaj   +1 more source

Fractal analyses of networks of integrate-and-fire stochastic spiking neurons

open access: yes, 2018
Although there is increasing evidence of criticality in the brain, the processes that guide neuronal networks to reach or maintain criticality remain unclear.
Amon, Mary Jean   +3 more
core   +1 more source

Neuronal avalanches of a self-organized neural network with active-neuron-dominant structure [PDF]

open access: yes, 2012
Neuronal avalanche is a spontaneous neuronal activity which obeys a power-law distribution of population event sizes with an exponent of -3/2. It has been observed in the superficial layers of cortex both \emph{in vivo} and \emph{in vitro}. In this paper
Beggs J.   +3 more
core   +2 more sources

A geographically distributed bio-hybrid neural network with memristive plasticity [PDF]

open access: yes, 2017
Throughout evolution the brain has mastered the art of processing real-world inputs through networks of interlinked spiking neurons. Synapses have emerged as key elements that, owing to their plasticity, are merging neuron-to-neuron signalling with ...
Corna, Andrea   +10 more
core   +1 more source

Associative properties of structural plasticity based on firing rate homeostasis in recurrent neuronal networks

open access: yes, 2018
Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity.
Gallinaro, Júlia V, Rotter, Stefan
core   +2 more sources

Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]

open access: yes, 2016
During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo   +5 more
core   +2 more sources

Social maintenance masks induced aggression in zebrafish

open access: yesScientific Reports
Animal behavior is dynamically shaped by internal states and external social contexts. This study examines how internal states and social buffering influence aggression and social behavior.
Ashil Arroth Kuniyil   +7 more
doaj   +1 more source

Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients

open access: yesBiomedicines, 2021
Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide without any validated biomarker or set of biomarkers to help the diagnosis and evaluation of the evolution/prognosis of TBI patients.
Víctor Farré-Alins   +20 more
doaj   +1 more source

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