Results 31 to 40 of about 999,561 (325)

Neuronal plasticity and antidepressant actions [PDF]

Trends in Neurosciences, 2013
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
René Hen, Eero Castrén
openaire   +3 more sources

Fractal analyses of networks of integrate-and-fire stochastic spiking neurons

, 2018
Although there is increasing evidence of criticality in the brain, the processes that guide neuronal networks to reach or maintain criticality remain unclear.
Amon, Mary Jean, Costa, Ariadne de Andrade, Favela, Luis, Sporns, Olaf   +3 more
core   +1 more source

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

eLife, 2018
Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the nervous system under non-pathological conditions has remained poorly understood.
Matthew C. W. Oswald, Paul Brooks, Maarten F. Zwart, A. Mukherjee, Ryan J H West, Carlo N G Giachello, Khomgrit Morarach, R. Baines, S. Sweeney, M. Landgraf   +9 more
semanticscholar   +1 more source

Neuronal Plasticity and Function

Clinical Neuropharmacology, 1993
Neuronal plasticity is a key issue in neuroscience. It is defined as the capability of the neuron to adapt to a changing internal or external environment, to previous experience or to trauma. It appears that during all phases of the individual life span in the nervous system, changes take place that relate to development, degeneration, and regeneration.
openaire   +4 more sources

Neuronal avalanches of a self-organized neural network with active-neuron-dominant structure [PDF]

, 2012
Neuronal avalanche is a spontaneous neuronal activity which obeys a power-law distribution of population event sizes with an exponent of -3/2. It has been observed in the superficial layers of cortex both \emph{in vivo} and \emph{in vitro}. In this paper
Beggs J., Destexhe A., Michael Small, Xiumin Li   +3 more
core   +2 more sources

Neuronal plasticity and neurotrophic factors in drug responses

Molecular Psychiatry, 2017
Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other members of the neurotrophin family, are central mediators of the activity-dependent plasticity through which environmental experiences, such as sensory information are ...
E. Castrén, H. Antila
semanticscholar   +1 more source

Critical neural networks with short and long term plasticity

, 2017
In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems.
de Arcangelis, L., Herrmann, H. J., Luković, M., van Kessenich, L. Michiels   +3 more
core   +2 more sources

Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis [PDF]

, 2010
Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo.
Bender, F.L.P., Brockington, A., Carmeliet, P., Claes, F., Heath, P.R., Holden, H., Kasher, P., Lambrechts, D., Sendtner, M., Shaw, P.J.   +9 more
core   +4 more sources

Triiodothyronine modulates neuronal plasticity mechanisms to enhance functional outcome after stroke

Acta Neuropathologica Communications, 2019
The development of new therapeutic approaches for stroke patients requires a detailed understanding of the mechanisms that enhance recovery of lost neurological functions. The efficacy to enhance homeostatic mechanisms during the first weeks after stroke
D. Talhada, J. Feiteiro, A. Costa, Tiago Talhada, E. Cairrão, T. Wieloch, E. Englund, C. Santos, I. Gonçalves, K. Ruscher   +9 more
semanticscholar   +1 more source

THE FUNDAMENTS OF NEURONAL PLASTICITY

Annals of the Russian academy of medical sciences, 2012
 Plasticity of the nervous system  is determined by the modification of efficacy of synaptic transmission: long- term potentiation and long- term depression. Different modern technical approaches such as: registration of ionic currents in single neuron, molecular- genetic analysis, neurovisualization, and others reveal the molecular mechanisms of ...
M. B. Shtark, V. G. Skrebitskii
openaire   +3 more sources