Results 41 to 50 of about 180,518 (195)

Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile [PDF]

, 2022
Michael Spedding, C. Sebban, Thérèse M. Jay, Cyril Rocher, B Tesolin‐Decros, Paul L. Chazot, Esther Schenker, Gábor Szénási, György Lévay, Katalin Megyeri, József Barkóczy, László G. Hársing, Ian Thomson, Mark O. Cunningham, Miles A. Whittington, Lori‐An Etherington, Jeremy J. Lambert, F. Antoni, István Gacsályi   +18 more
openalex   +1 more source

Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels

Neural Plasticity, 2021
Hippocampal cell death and cognitive dysfunction are common following global cerebral ischemia across all ages, including children. Most research has focused on preventing neuronal death.
Robert M. Dietz, James E. Orfila, Nicholas Chalmers, Crystal Minjarez, Jose Vigil, Guying Deng, Nidia Quillinan, Paco S. Herson   +7 more
doaj   +1 more source

Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein

eLife, 2017
The amyloid precursor protein (APP) harbors physiological roles at synapses and is central to Alzheimer’s disease (AD) pathogenesis. Evidence suggests that APP intracellular domain (AICD) could regulate synapse function, but the underlying molecular ...
Paula A Pousinha, Xavier Mouska, Elisabeth F Raymond, Carole Gwizdek, Gihen Dhib, Gwenola Poupon, Laure-Emmanuelle Zaragosi, Camilla Giudici, Ingrid Bethus, Emilie Pacary, Michael Willem, Hélène Marie   +11 more
doaj   +1 more source

Cell Type-specific Metabolic Labeling of Proteins with Azidonorleucine in Drosophila

Bio-Protocol, 2017
Advanced mass spectrometry technology has pushed proteomic analyses to the forefront of biological and biomedical research. Limitations of proteomic approaches now often remain with sample preparations rather than with the sensitivity of protein ...
Ines Erdmann, Kathrin Marter, Oliver Kobler, Sven Niehues, Julia Bussmann, Anke Müller, Julia Abele, Erik Storkebaum, Ulrich Thomas, Daniela Dieterich   +9 more
doaj   +1 more source

Strategies for the Identification of Bioactive Neuropeptides in Vertebrates

Frontiers in Neuroscience, 2019
Neuropeptides exert essential functions in animal physiology by controlling e.g., reproduction, development, growth, energy homeostasis, cardiovascular activity and stress response.
Auriane Corbière, Hubert Vaudry, Hubert Vaudry, Philippe Chan, Marie-Laure Walet-Balieu, Thierry Lecroq, Arnaud Lefebvre, Charles Pineau, David Vaudry, David Vaudry, David Vaudry   +10 more
doaj   +1 more source

Neuronal plasticity in nematode worms [PDF]

Nature, 2018
Neuronal activity induces changes in the connectivity of a neuron called DVB in adult male nematode worms. This discovery provides an opportunity to study a fundamental process in this powerful model organism. Neuronal activity induces changes in the connectivity of a neuron called DVB in adult male nematode worms.
openaire   +2 more sources

The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows Reduced Fear-Promoting Effects in Mice

Frontiers in Pharmacology, 2019
Rimonabant was the first selective CB1 antagonist/inverse agonist introduced into clinical practice to treat obesity and metabolic-related disorders. It was withdrawn from market due to the notably increased rates of psychiatric side effects.
Vincenzo Micale, Vincenzo Micale, Vincenzo Micale, Filippo Drago, Pia K. Noerregaard, Christian E. Elling, Carsten T. Wotjak   +6 more
doaj   +1 more source

Stimulation of the ventral tegmental area induces visual cortical plasticity at the neuronal level [PDF]

, 2021
Jerome Herpers, John T. Arsenault, Wim Vanduffel, Rufin Vogels   +3 more
openalex   +1 more source

The chromatin landscape of neuronal plasticity

Current Opinion in Neurobiology, 2019
Examining the links between neuronal activity, transcriptional output, and synaptic function offers unique insights into how neurons adapt to changing environments and form memories. Epigenetic markers, such as DNA methylation and histone modifications, have been implicated in the formation of not only cellular memories such as cell fate, but also ...
Margaret, Herre, Erica, Korb
openaire   +3 more sources

SYNAPTIC IMBALANCE AND THE NITRIC OXIDE PATHWAY IN THE VPA MOUSE MODEL OF AUTISM

IBRO Neuroscience Reports, 2023
Valeria Lorena Cabedo Navarro, David Pérez-Boyero, Laura Pérez-Revuelta, Eduardo Weruaga Prieto, David Díaz López, José Ramón Alonso Peña   +5 more
doaj   +1 more source