Results 41 to 50 of about 191,422 (338)
Associative properties of structural plasticity based on firing rate homeostasis in recurrent neuronal networks [PDF]
, 2017 Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity. Here we investigate another, new aspect of this dichotomy: Can Hebbian associative properties also emerge as a network effect from a plasticity rule based on homeostatic ...
arxiv +1 more source
Neuron–glia metabolic coupling and plasticity [PDF]
Journal of Experimental Biology, 2006 SUMMARY The coupling between synaptic activity and glucose utilization(neurometabolic coupling) is a central physiological principle of brain function that has provided the basis for 2-deoxyglucose-based functional imaging with positron emission tomography (PET).
openaire +9 more sources
Biomedicines, 2021 Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide without any validated biomarker or set of biomarkers to help the diagnosis and evaluation of the evolution/prognosis of TBI patients.
Víctor Farré-Alins +20 more
doaj +1 more source
Astrocytes: orchestrating synaptic plasticity? [PDF]
, 2015 Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain ...
arxiv +1 more source
THE FUNDAMENTS OF NEURONAL PLASTICITY
Annals of the Russian academy of medical sciences, 2012 Plasticity of the nervous system is determined by the modification of efficacy of synaptic transmission: long- term potentiation and long- term depression. Different modern technical approaches such as: registration of ionic currents in single neuron, molecular- genetic analysis, neurovisualization, and others reveal the molecular mechanisms of ...
M. B. Shtark, V. G. Skrebitskii
openaire +3 more sources
Foldscope as an Innovative Teaching Tool
Education Sciences, 2022 This study deals with the descriptive analysis of the opinion of a pilot group of students at the University of Salamanca about the use of an innovative origami microscope: the Foldscope.
Carlos Hernández-Pérez +1 more
doaj +1 more source
Dis-inhibitory neuronal circuits can control the sign of synaptic plasticity [PDF]
arXiv, 2023 How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely functionally motivated models assume distinct neuronal compartments to represent local error signals that determine ...
arxiv
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Frontiers in Neurology, 2022 BackgroundPatient-reported quality of life (QoL) may help to capture sequela of stroke more comprehensively. We aimed to investigate QoL in working age persons with ischemic stroke regarding impaired domains and identify factors associated with better ...
Daniela Pinter +15 more
doaj +1 more source
A Spiking Neuron Synaptic Plasticity Model Optimized for Unsupervised Learning [PDF]
arXiv, 2021 Spiking neural networks (SNN) are considered as a perspective basis for performing all kinds of learning tasks - unsupervised, supervised and reinforcement learning. Learning in SNN is implemented through synaptic plasticity - the rules which determine dynamics of synaptic weights depending usually on activity of the pre- and post-synaptic neurons ...
arxiv