Structural basis of neuropeptide Y signaling through Y1 receptor
Nature Communications, 2022 The human neuropeptide Y (NPY) acts through G-protein coupled receptors and is involved in food intake, stress response, anxiety, and memory retention.
Chaehee Park +12 more
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The neuropeptide transcriptome of a model echinoderm, the sea urchin Strongylocentrotus purpuratus [PDF]
, 2012 The work reported here was supported by a grant from the University of London Central Research ...
Elphick, MR, Rowe, ML
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Neuropeptide Y Y2 receptor in health and disease [PDF]
British Journal of Pharmacology, 2008 British Journal of Pharmacology (2008) 155, 1307; doi:10.1038/bjp.2008 ...
Ambikaipakan Balasubramaniam +1 more
openaire +4 more sources
The Role of NPY in the Regulation of Bone Metabolism
Frontiers in Endocrinology, 2022 Bone diseases are the leading causes of disability and severely compromised quality of life. Neuropeptide Y (NPY) is a multifunctional neuropeptide that participates in various physiological and pathological processes and exists in both the nerve system ...
Qing-Chang Chen +2 more
doaj +1 more source
Sex Differences in the Neuropeptide Y System and Implications for Stress Related Disorders
Biomolecules, 2020 The neuropeptide Y (NPY) system is emerging as a promising therapeutic target for neuropsychiatric disorders by intranasal delivery to the brain. However, the vast majority of underlying research has been performed with males despite females being twice ...
Roxanna J. Nahvi, Esther L. Sabban
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What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]
, 2019 Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra +13 more
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Cell Death and Disease, 2013 It has been claimed that glutamate excitotoxicity might have a role in the pathogenesis of several retinal degenerative diseases, including glaucoma and diabetic retinopathy.
A. Santos-Carvalho +4 more
semanticscholar +1 more source
Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]
, 2014 Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
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Proceedings of the National Academy of Sciences of the United States of America, 1988 Neuropeptide Y (NPY) inhibited the Ca2+ current (ICa) in rat dorsal root ganglion neurons in vitro. NPY inhibited the sustained ICa evoked by steps to 0 mV from a holding potential of -40 mV and the inactivating ICa, which was additionally evoked from a ...
D. Ewald +2 more
semanticscholar +1 more source
Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion
Brazilian Journal of Medical and Biological Research, 1999 We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
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