Results 81 to 90 of about 14,350 (168)

Proteomic and Phosphoproteomic Characteristics of Multiple Brain Regions in Rhesus Macaques After SARS‐CoV‐2 Infection

MedComm, Volume 7, Issue 8, August 2026.
The study found that SARS‐CoV‐2 Omicron infection causes region‐specific inflammatory, immune, synaptic, and signaling disorders in the brain, and the predicted kinases and differentially expressed proteins may serve as potential targets for COVID‐19‐related drug discovery.
Qiaochu Wang, Yanan Zhou, Tao Ding, Yan Sun, Yehong Yang, Yue Wu, Jiangfeng Liu, Shuaiyao Lu, Juntao Yang   +8 more
wiley   +1 more source

The role of neuropilin-1 (NRP1) in the development of SARS-CoV-2 infection

Якутский медицинский журнал
A review of the literature on the role of neuropilin-1 in the development of SARS-CoV-2 infection and a search for probable links between polymorphic variants of the NRP1 gene and SARS-CoV-2 are presented.
V. A. Markelov, A. V. Danilko
doaj   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, Volume 293, Issue 15, Page 4604-4623, August 2026.
The Notch signaling pathway plays a crucial role in regulating endothelial biology. Notch signaling is sensitive to hemodynamic forces and governs mechanically driven cardiovascular development, physiology, and remodeling. This study reveals a non‐canonical role for the Notch ligand Jagged1 in endothelial mechanotransduction.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

Neuropilin-2 Mediates Radioresistance in Nasopharyngeal Carcinoma via Wnt/β-Catenin Pathway

Cancer Management and Research
Jiawei Chen,* Huimin Fu,* Xiaopeng Huang, Zetan Chen Department of Radiation Oncology, Hainan General Hospital, Affiliated Hospital of HainanMedical University, Haikou, Hainan, 570311, People’s Republic of China*These authors ...
Chen J, Fu H, Huang X, Chen Z
doaj  

Basic implications on three pathways associated with SARS-CoV-2

Biomedical Journal
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts.
Jong hoon Lee, Consolato Sergi, Richard E. Kast, Badar A. Kanwar, Jean Bourbeau, Sangsuk Oh, Mun-Gi Sohn, Chul Joong Lee, Michael D. Coleman   +8 more
doaj   +1 more source

Neuropilin-2 is an entry receptor for Chikungunya virus

Abstract Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes acute febrile illness and chronic arthralgia, yet no approved antivirals exist. Although MXRA8 was previously identified as a CHIKV receptor, it cannot account for viral infection in MXRA8 absence both in vitro
Yibo Chen, Ke Zhang, Hailin Tang, Zhiwei He, Shudan Luo, Zhongtian Qi, Ping Zhao, Cuiling Ding   +7 more
openaire   +1 more source

Jack of many trades: Multifaceted role of neuropilins in pancreatic cancer

Cancer Medicine, 2018
Neuropilins (NRPs) have been described as receptors for class 3 semaphorins and coreceptors for a plethora of ligands, such as members of the vascular endothelial growth factor (VEGF) family of angiogenic cytokines and transforming growth factor (TGF ...
Pratiek N. Matkar, Eric D. Jong, Ramya Ariyagunarajah, Gerald J. Prud'homme, Krishna K. Singh, Howard Leong‐Poi   +5 more
doaj   +1 more source

Neuropilin 1: A Novel Entry Factor for SARS-CoV-2 Infection and a Potential Therapeutic Target

Biologics: Targets & Therapy, 2021
Endeshaw Chekol Abebe,1 Teklie Mengie Ayele,2 Zelalem Tilahun Muche,3 Tadesse Asmamaw Dejenie4 1Department of Medical Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Pharmacy, College of Health ...
Chekol Abebe E, Mengie Ayele T, Tilahun Muche Z, Asmamaw Dejenie T   +3 more
doaj  

Macrophage polarization in immune-inflammatory diseases with lung damage: The promising therapeutic strategies

Научно-практическая ревматология
The article discusses the role of macrophage polarization in the processes of inflammation and fibrosis. Targeting the polarization of alternatively activated M2 macrophages could be a promising strategy to prevent fibrosis progression. The prospects for
T. V. Beketova, E. I. Shchepikhin, L. P. Ananyeva   +2 more
doaj   +1 more source

Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer. [PDF]

Oncogene, 2022
Wang J, Li J, Yin L, Pu T, Wei J, Karthikeyan V, Lin TP, Gao AC, Wu BJ.   +8 more
europepmc   +1 more source