Results 11 to 20 of about 14,670 (186)
Frontiers in Immunology, 2021 Semaphorins are a group of proteins that have been studied extensively for their critical function in neuronal development. They have been shown to regulate airway development, tumorigenesis, autoimmune diseases, and the adaptive immune response. Notably,
Shreya M. Kanth +2 more
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Hepatology, EarlyView., 2022 Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid +20 more
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Neuropilin-2 Is Associated With Increased Hepatoblastoma Cell Viability and Motility
Frontiers in Pediatrics, 2021 The neuropilins NRP1 and NRP2 are multifunctional glycoproteins that have been implicated in several cancer-related processes including cell survival, migration, and invasion in various tumor types.
Katja Eloranta +9 more
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Contribution of Neuropilin-1 in Radiation-Survived Subclones of NSCLC Cell Line H1299
Current Issues in Molecular Biology, 2021 Non-small cell lung cancer (NSCLC) is an aggressive lung cancer accounting for approximately 85% of all lung cancer patients. For the patients with Stages IIIA, IIIB, and IIIC, the 5-year survival is low though with the combination with radiotherapy and ...
Kaori Tsutsumi +5 more
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Non-Coding RNA, 2021 Neuropilin-1 is a transmembrane glycoprotein that has been implicated in several processes including angiogenesis and immunity. Recent evidence has also shown that it is implied in the cellular internalization of the severe acute respiratory syndrome ...
Pasquale Mone +5 more
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Lymphatic Vasculature in Energy Homeostasis and Obesity
Frontiers in Physiology, 2020 Obesity is a leading cause of cardiovascular diseases and cancer. Body mass is regulated by the balance between energy uptake and energy expenditure. The etiology of obesity is determined by multiple factors including genetics, nutrient absorption, and ...
Yen-Chun Ho +2 more
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médecine/sciences, 2020 Une angiogenèse exacerbée est une des caractéristiques («hallmarks») du cancer, définies par Hanahan et Weinberg1. Cependant, le ciblage de la voie de signalisation du VEGF (vascular endothelial growth factor) ou de ses récepteurs a montré ses limites thérapeutiques.
Dumond, Aurore +2 more
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Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. [PDF]
PLoS ONE, 2015 PAX8 is a transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated state in the adult.
Valeria Lucci +2 more
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Cell Adhesion & Migration, 2007 It is now well established that neuropilins (NRP1 and NRP2), first described as mediators of neuronal guidance, are also mediators of angiogenesis and tumor progression. NRPs are receptors for the class-3 semaphorin (SEMA) family of axon guidance molecules and also for the vascular endothelial growth factor (VEGF) family of angiogenic factors. VEGF-NRP
Elena, Geretti, Michael, Klagsbrun
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Semaphorin signaling in vertebrate neural circuit assembly
Frontiers in Molecular Neuroscience, 2012 Neural circuit formation requires the coordination of many complex developmental processes. First, neurons project axons over long distances to find their final targets and then establish appropriate connectivity essential for the formation of neuronal ...
Yutaka eYoshida
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