Results 11 to 20 of about 17,164 (224)
Non-Coding RNA, 2021 Neuropilin-1 is a transmembrane glycoprotein that has been implicated in several processes including angiogenesis and immunity. Recent evidence has also shown that it is implied in the cellular internalization of the severe acute respiratory syndrome ...
Pasquale Mone +5 more
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Neuropilin Is a Semaphorin III Receptor [PDF]
Cell, 1997 The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been shown to function in repulsive axon guidance. Semaphorin III (Sema III) is a secreted protein that in vitro causes neuronal growth cone collapse and chemorepulsion of neurites, and in vivo is required for correct sensory ...
Kolodkin, Alex L +5 more
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Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. [PDF]
PLoS ONE, 2015 PAX8 is a transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated state in the adult.
Valeria Lucci +2 more
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Significance of Neuropilin-1 Expression in Acute Myeloid Leukemia
Turkish Journal of Hematology, 2013 Objective: Neuropilin-1 is a vascular endothelial growth factor receptor that acts as a mediator of angiogenesis. Its importance in hematological malignancies such as acute myeloid leukemia (AML) remains to be elucidated.
Tarif H. Sallam +3 more
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Neuropilin-1 in Transplantation Tolerance [PDF]
Frontiers in Immunology, 2013 In the immune system, Neuropilin-1 (Nrp1) is a molecule that plays an important role in establishing the immunological synapse between dendritic cells (DCs) and T cells.
Mauricio eCampos-Mora +4 more
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Lymphatic Vasculature in Energy Homeostasis and Obesity
Frontiers in Physiology, 2020 Obesity is a leading cause of cardiovascular diseases and cancer. Body mass is regulated by the balance between energy uptake and energy expenditure. The etiology of obesity is determined by multiple factors including genetics, nutrient absorption, and ...
Yen-Chun Ho +2 more
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Contribution of Neuropilin-1 in Radiation-Survived Subclones of NSCLC Cell Line H1299
Current Issues in Molecular Biology, 2021 Non-small cell lung cancer (NSCLC) is an aggressive lung cancer accounting for approximately 85% of all lung cancer patients. For the patients with Stages IIIA, IIIB, and IIIC, the 5-year survival is low though with the combination with radiotherapy and ...
Kaori Tsutsumi +5 more
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médecine/sciences, 2020 Une angiogenèse exacerbée est une des caractéristiques («hallmarks») du cancer, définies par Hanahan et Weinberg1. Cependant, le ciblage de la voie de signalisation du VEGF (vascular endothelial growth factor) ou de ses récepteurs a montré ses limites thérapeutiques.
Dumond, Aurore +2 more
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The Significance of Neuropilins in Gastrointestinal Cancers. [PDF]
Int J Mol SciCancers represent a significant global health concern, being among the most prevalent malignancies and contributing substantially to morbidity and mortality rates. Notably, colorectal, gastric, pancreatic, and liver cancers are the most frequently diagnosed among these malignancies.
Królikowska K +5 more
europepmc +4 more sources
Cell Adhesion & Migration, 2007 It is now well established that neuropilins (NRP1 and NRP2), first described as mediators of neuronal guidance, are also mediators of angiogenesis and tumor progression. NRPs are receptors for the class-3 semaphorin (SEMA) family of axon guidance molecules and also for the vascular endothelial growth factor (VEGF) family of angiogenic factors. VEGF-NRP
Elena, Geretti, Michael, Klagsbrun
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