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The Function of Neuropilin/L1 Complex
2002L1, a cell adhesion molecule of the Ig superfamily (IgCAM) plays a critical role in the formation of neuronal networks. This is reflected by the variety of clinical signs associated with the X-linked recessive neurological disorder that is caused by mutations in the L1 gene.
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Flow regulation of Neuropilin-1 and the role of Neuropilin-1 in mechanotransduction
2011Le concept de l'angiogénèse est simple et bien défini, comme la formation de nouveaux vaisseaux sanguins à partir de vaisseaux préexistants, mais son mécanisme est complexe, et implique une multitude de facteurs qui sont encore méconnus. Une des choses que nous savons avec certitude, est que l'angiogénèse est une composante vitale de la vie, autant que
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Neuropilin invites reoviruses into neurons
Cell Host & MicrobeIn this issue of Cell Host & Microbe, Shang et al. identify murine neuropilin 1 as a host factor that binds reovirus particles, directing cell entry and contributing to viral dissemination and neurovirulence. This study highlights the reovirus model system to investigate host receptors and their significance in viral pathogenesis.
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The Function of Neuropilin/Plexin Complexes
2002Neuropilins bind the secreted class 3 semaphorins with high affinity but require a member of the plexin family to form receptors that are able to activate downstream signal transduction cascades. In this receptor complex neuropilins act as the ligand-binding subunit while plexins function as the signal-transducing subunit in the induction of ...
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Neuropilins, Semaphorins, and Their Role in Thymocyte Development
Annals of the New York Academy of Sciences, 2009Lepelletier Y +2 more
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