Results 21 to 30 of about 134,809 (339)
Frontiers in Pharmacology, 2020 Histone deacetylases (HADC) are the enzymes that remove acetyl group from lysine residue of histones and non-histone proteins and regulate the process of transcription by binding to transcription factors and regulating fundamental cellular process such ...
S. Shukla, B. Tekwani
semanticscholar +1 more source
Basic Research in Cardiology, 2021 Stroke remains one of the most common causes of death and disability worldwide. Several preclinical studies demonstrated that the brain can be effectively protected against ischaemic stroke by two seemingly distinct treatments: remote ischaemic ...
S. Nizari +11 more
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A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants.
New England Journal of Medicine, 2020 BACKGROUND High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy; however, the benefits and safety of this therapy in extremely preterm
Sandra E. Juul +27 more
semanticscholar +1 more source
Data in Brief, 2020 This article provides information regarding the effect of four common high abundant protein (albumin and immunoglobulins (Ig)) depletion strategies upon serum proteomics datasets derived from normal, non-diseased rat or human serum. After tryptic digest,
Bharani Thangavelu +4 more
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Hibernation, a Model of Neuroprotection [PDF]
TheScientificWorldJOURNAL, 2001 Hibernation, a natural model of tolerance to cerebral ischemia, represents a state of pronounced fluctuation in cerebral blood flow where no brain damage occurs. Numerous neuroprotective aspects may contribute in concert to such tolerance. The purpose of this study was to determine whether hibernating brain tissue is tolerant to penetrating brain ...
Fang Zhou +6 more
+12 more sources
Polyphenols from Food and Natural Products: Neuroprotection and Safety
Antioxidants, 2020 Polyphenols are naturally occurring micronutrients that are present in many food sources. Besides being potent antioxidants, these molecules may also possess anti-inflammatory properties.
Rui F. M. Silva, L. Pogačnik
semanticscholar +1 more source
Neuroprotection by the Ketogenic Diet: Evidence and Controversies
Frontiers in Nutrition, 2021 The ketogenic diet (KD) is a high-fat low-carbohydrate diet that has been used for decades as a non-pharmacologic approach to treat metabolic disorders and refractory pediatric epilepsy.
S. Gough +3 more
semanticscholar +1 more source
Liquid–liquid phase separation in synaptopathies
Neuroprotection, 2023 Liquid–liquid phase separation has emerged as an important mechanism for regulating cell activity by promoting the formation of membrane‐less condensates.
Huihui Jiang, Haitao Wu
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Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
Translational Neurodegeneration, 2020 Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and oxidative stress, which are important factors contributing to the development of brain disease.
Luodan Yang +3 more
semanticscholar +1 more source
Journal of Ophthalmic and Vision Research, 2016 Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC) loss and visual field defects. It is known that in some glaucoma patients, death of RGCs continues despite intraocular pressure (IOP) reduction. Neuroprotection in the field of glaucoma is defined as any treatment, independent of IOP reduction, which prevents RGC ...
Shahin Yazdani, Azadeh Doozandeh
openaire +4 more sources