Results 11 to 20 of about 177,883 (410)
Mitophagy and Neuroprotection. [PDF]
Trends in Molecular Medicine, 2019 Neurodegenerative diseases are strongly age-related and currently cannot be cured, with a surge of patient numbers in the coming decades in view of the emerging worldwide ageing population, bringing healthcare and socioeconomic challenges.
Guofeng Lou +5 more
semanticscholar +4 more sources
Neuroprotection in glaucoma: a model for neuroprotection in optic neuropathies
Current Opinion in Ophthalmology, 2003 Purpose of review: Efforts to discover modalities and pathophysiologies that might afford successful neurorescue, neurorestoration, and neuroprotection of cells of the central nervous system have focused on processes that affect the central nervous ...
Belyea, D.A. +5 more
core +3 more sources
Hypothermic neuroprotection [PDF]
Neurotherapeutics, 2006 The possibility that hypothermia during or after resuscitation from asphyxia at birth, or cardiac arrest in adults, might reduce evolving damage has tantalized clinicians for a very long time. It is now known that severe hypoxia-ischemia may not necessarily cause immediate cell death, but can precipitate a complex biochemical cascade leading to the ...
Gunn, AJ, Thoresen, M
openaire +2 more sources
Mitochondrial surface coating with artificial lipid membrane improves the transfer efficacy
Communications Biology, 2022 A new approach is developed to promote mitochondria transfer and the efficacy by surface decoration of cationic and fusogenic lipids, DOTAP and DOPE, showing improved neuroprotection in vitro and in vivo.
Takafumi Nakano +4 more
doaj +1 more source
A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants
New England Journal of Medicine, 2020 BACKGROUND High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy; however, the benefits and safety of this therapy in extremely preterm
Sandra E. Juul +27 more
semanticscholar +1 more source
, 2019 Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In
core +2 more sources
Basic Research in Cardiology, 2021 Stroke remains one of the most common causes of death and disability worldwide. Several preclinical studies demonstrated that the brain can be effectively protected against ischaemic stroke by two seemingly distinct treatments: remote ischaemic ...
S. Nizari +11 more
semanticscholar +1 more source
British Medical Bulletin, 2000 Thrombolysis improves stroke outcome, but is applicable to a limited number of patients. Neuroprotection has the prospect to be universally offered, either alone or in combination with thrombolysis. Potential drug targets include elements of the excitotoxic glutamate cascade, calcium entry, intracellular protease activation, free radical damage, the ...
openaire +2 more sources
Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective.
Pharmacology and Therapeutics, 2020 There is a growing interest in using natural medicines to treat stroke as the leading cause of disability worldwide. Especially plant-derived natural medicines have multiple beneficial effects, including antioxidative, anti-inflammatory, antiapoptotic ...
Tao Tao +8 more
semanticscholar +1 more source
Neuroprotection in glaucoma [PDF]
Cell and Tissue Research, 2013 Glaucoma is a frequent eye disease in the elderly and the second leading cause of irreversible blindness both in developed and developing countries (Resnikoff et al. 2004). Presently, about 50 million people are blind from glaucoma worldwide, a number that has not significantly changed over the last decade (Resnikoff et al. 2004; Thylefors et al. 1995).
Ernst R, Tamm +2 more
openaire +2 more sources