Results 11 to 20 of about 118,682 (313)

Mitophagy and Neuroprotection [PDF]

Trends in Molecular Medicine, 2020
Neurodegenerative diseases are strongly age-related and currently cannot be cured, with a surge of patient numbers in the coming decades in view of the emerging worldwide ageing population, bringing healthcare and socioeconomic challenges. Effective therapies are urgently needed, and are dependent on new aetiological mechanisms.
Lou, Guofeng, Palikaras, Konstantinos, Lautrup, Sofie, Scheibye-Knudsen, Morten, Tavernarakis, Nektarios, Fang, Evandro F.   +5 more
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Nanodelivery of oxiracetam enhances memory, functional recovery and induces neuroprotection following concussive head injury [PDF]

, 2021
Military personnel are the most susceptible to concussive head injury (CHI) caused by explosion, blast or missile or blunt head trauma. Mild to moderate CHI could induce lifetime functional and cognitive disturbances causing significant decrease in ...
Nozari, Ala, Preeti K. Menon, Castellani, Rudy J., Rudy J. Castellani, Menon, Preeti K.,, Aruna Sharma, Wang, Zhenguo, Lars Wiklund, Muresanu, Dafin F., Lianyuan Feng, Lafuente, José Vicente, Patnaik, Ranjana, Vicente Lafuente, José, Seaab Sahib, Sharma, Hari Shanker, Sahib, Seaab, Niu, Feng, Buzoianu, Anca D., Sharma, Aruna,, Ala Nozari, Ranjana Patnaik, Feng Niu, Dafin F. Muresanu, Sharma, Aruna, Menon, Preeti K., Wiklund, Lars, Hari Shanker Sharma, Feng, Lianyuan, Z. Ryan Tian, Tian, Z. Ryan, Wiklund, Lars,, Sharma, Hari Shanker,, Anca D. Buzoianu, José Vicente Lafuente, Zhenguo Wang   +34 more
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Concussive head injury exacerbates neuropathology of sleep deprivation : Superior neuroprotection by co-administration of TiO2-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells [PDF]

, 2020
Sleep deprivation (SD) is common in military personnel engaged in combat operations leading to brain dysfunction. Military personnel during acute or chronic SD often prone to traumatic brain injury (TBI) indicating the possibility of further exacerbating
Patnaik, Ranjana,, Sharma, Aruna,, Bryukhovetskiy, Igor,, Tian, Z. Ryan,, Nozari, Ala,, Castellani, Rudy J.,, Vicente Lafuente, Jose,, Buzoianu, Anca D.,, Muresanu, Dafin F.,, Wiklund, Lars,, Sharma, Hari Shanker,, Sahib, Seaab,, Manzhulo, Igor,   +12 more
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Neuroprotection in Brain Hypoxia [PDF]

, 2019
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

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Hypothermic neuroprotection [PDF]

Neurotherapeutics, 2006
The possibility that hypothermia during or after resuscitation from asphyxia at birth, or cardiac arrest in adults, might reduce evolving damage has tantalized clinicians for a very long time. It is now known that severe hypoxia-ischemia may not necessarily cause immediate cell death, but can precipitate a complex biochemical cascade leading to the ...
Gunn, AJ, Thoresen, M
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Nanodelivery of histamine H3 receptor inverse agonist BF-2649 with H3 receptor antagonist and H4 receptor agonist clobenpropit induced neuroprotection is potentiated by antioxidant compound H-290/51 in spinal cord injury [PDF]

, 2023
Military personnel are often victims of spinal cord injury resulting in lifetime disability and decrease in quality of life. However, no suitable therapeutic measures are still available to restore functional disability or arresting the ...
Buzoianu, Anca D.,, Sharma, Aruna,, Vicente Lafuente, José,, Tian, Z. Ryan,, Muresanu, Dafin F.,, Nozari, Ala,, Wiklund, Lars,, Sharma, Hari Shanker,, Huang, Hongyun,, Chen, Lin,, Feng, Lianyuan,, Sjöqvist, Per-Ove,   +11 more
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Microglia and neuroprotection [PDF]

Journal of Neurochemistry, 2015
AbstractMicroglia were first identified over a century ago, but our knowledge about their ontogeny and functions has significantly expanded only recently. Microglia colonize the central nervous system (CNS) in utero and play essential roles in brain development.
Zhihong Chen, Bruce D. Trapp
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Neuroprotection [PDF]

, 2019
Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In

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Neuroprotection [PDF]

British Medical Bulletin, 2000
Thrombolysis improves stroke outcome, but is applicable to a limited number of patients. Neuroprotection has the prospect to be universally offered, either alone or in combination with thrombolysis. Potential drug targets include elements of the excitotoxic glutamate cascade, calcium entry, intracellular protease activation, free radical damage, the ...
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Neuroprotection in glaucoma

Indian Journal of Ophthalmology, 2022
Neuroprotective therapies in glaucoma may play a role in preventing ischemia and oxidative damage that results in apoptosis of retinal ganglion cells and optic nerve damage. Although intraocular pressure (IOP) is the only known modifiable risk factor for glaucoma, disease progression commonly occurs despite IOP control, suggesting that factors other ...
Vishwaraj, C R, Kavitha, Srinivasan, Venkatesh, Rengaraj, Shukla, Aakriti Garg, Chandran, Premanand, Tripathi, Shweta   +5 more
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