Results 11 to 20 of about 128,007 (210)

Neuroprotection [PDF]

Archives of Neurology, 2007
The ability of pharmacological agents to limit secondary biochemical damage and cell death has been well established in numerous animal models of stroke, head injury, and spinal cord injury, yet the results of such neuroprotective treatment strategies in human injury have been disappointing.
Alan I, Faden, Bogdan, Stoica
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Neuroprotection by estradiol [PDF]

Progress in Neurobiology, 2001
This review highlights recent evidence from clinical and basic science studies supporting a role for estrogen in neuroprotection. Accumulated clinical evidence suggests that estrogen exposure decreases the risk and delays the onset and progression of Alzheimer's disease and schizophrenia, and may also enhance recovery from traumatic neurological injury
García-Segura, Luis M., Azcoitia, I., Doncarlos, Lydia L.   +2 more
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Neuroprotection in glaucoma

Journal of Ophthalmic and Vision Research, 2016
Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC) loss and visual field defects. It is known that in some glaucoma patients, death of RGCs continues despite intraocular pressure (IOP) reduction. Neuroprotection in the field of glaucoma is defined as any treatment, independent of IOP reduction, which prevents RGC ...
Azadeh Doozandeh, Shahin Yazdani
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Manganese Porphyrin Promotes Post Cardiac Arrest Recovery in Mice and Rats

Biology, 2022
Introduction Cardiac arrest (CA) and resuscitation induces global cerebral ischemia and reperfusion, causing neurologic deficits or death. Manganese porphyrins, superoxide dismutase mimics, are reportedly able to effectively reduce ischemic injury in ...
Peng Wang, Ying Li, Baihui Yan, Zhong Yang, Litao Li, Zhipeng Cao, Xuan Li, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, Huaxin Sheng   +10 more
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Concussive head injury exacerbates neuropathology of sleep deprivation : Superior neuroprotection by co-administration of TiO2-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells

, 2020
Sleep deprivation (SD) is common in military personnel engaged in combat operations leading to brain dysfunction. Military personnel during acute or chronic SD often prone to traumatic brain injury (TBI) indicating the possibility of further exacerbating
Patnaik, Ranjana,, Sharma, Aruna,, Bryukhovetskiy, Igor,, Tian, Z. Ryan,, Nozari, Ala,, Castellani, Rudy J.,, Vicente Lafuente, Jose,, Buzoianu, Anca D.,, Muresanu, Dafin F.,, Wiklund, Lars,, Sharma, Hari Shanker,, Sahib, Seaab,, Manzhulo, Igor,   +12 more
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Neuroprotection in glaucoma

Indian Journal of Ophthalmology, 2022
Neuroprotective therapies in glaucoma may play a role in preventing ischemia and oxidative damage that results in apoptosis of retinal ganglion cells and optic nerve damage. Although intraocular pressure (IOP) is the only known modifiable risk factor for glaucoma, disease progression commonly occurs despite IOP control, suggesting that factors other ...
Vishwaraj, C R, Kavitha, Srinivasan, Venkatesh, Rengaraj, Shukla, Aakriti Garg, Chandran, Premanand, Tripathi, Shweta   +5 more
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Nanodelivery of oxiracetam enhances memory, functional recovery and induces neuroprotection following concussive head injury

, 2021
Military personnel are the most susceptible to concussive head injury (CHI) caused by explosion, blast or missile or blunt head trauma. Mild to moderate CHI could induce lifetime functional and cognitive disturbances causing significant decrease in ...
Nozari, Ala, Preeti K. Menon, Castellani, Rudy J., Rudy J. Castellani, Menon, Preeti K.,, Aruna Sharma, Wang, Zhenguo, Lars Wiklund, Muresanu, Dafin F., Lianyuan Feng, Lafuente, José Vicente, Patnaik, Ranjana, Vicente Lafuente, José, Seaab Sahib, Sharma, Hari Shanker, Sahib, Seaab, Niu, Feng, Buzoianu, Anca D., Sharma, Aruna,, Ala Nozari, Ranjana Patnaik, Feng Niu, Dafin F. Muresanu, Sharma, Aruna, Menon, Preeti K., Wiklund, Lars, Hari Shanker Sharma, Feng, Lianyuan, Z. Ryan Tian, Tian, Z. Ryan, Wiklund, Lars,, Sharma, Hari Shanker,, Anca D. Buzoianu, José Vicente Lafuente, Zhenguo Wang   +34 more
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Neuroprotection in Brain Hypoxia

, 2019
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

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Cell Specific Changes of Autophagy in a Mouse Model of Contusive Spinal Cord Injury

Frontiers in Cellular Neuroscience, 2018
Autophagy is an essential process of cellular waist clearance that becomes altered following spinal cord injury (SCI). Details on these changes, including timing after injury, underlying mechanisms, and affected cells, remain controversial.
Teresa Muñoz-Galdeano, David Reigada, Ángela del Águila, Ángela del Águila, Irene Velez, Marcos J. Caballero-López, Rodrigo M. Maza, Manuel Nieto-Díaz   +7 more
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Progesterone and neuroprotection [PDF]

Hormones and Behavior, 2013
Numerous studies aimed at identifying the role of estrogen on the brain have used the ovariectomized rodent as the experimental model. And while estrogen intervention in these animals has, at least partially, restored cholinergic, neurotrophin and cognitive deficits seen in the ovariectomized animal, it is worth considering that the removal of the ...
Meharvan, Singh, Chang, Su
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