Results 21 to 30 of about 177,883 (410)

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

bioRxiv, 2020
Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. Repleting NAD via dietary supplementation of nicotinamide (
James R. Tribble, Amin Otmani, Shanshan Sun, Sevannah A Ellis, G. Cimaglia, R. Vohra, Melissa Jöe, E. Lardner, A. Venkataraman, Alberto Domínguez-Vicent, E. Kokkali, S. Rho, G. Jóhannesson, R. Burgess, P. Fuerst, R. Brautaset, M. Kolko, J. Morgan, J. Crowston, M. Votruba, Pete A. Williams   +20 more
semanticscholar   +1 more source

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation.

Neurobiology of Disease, 2020
Microglia-induced neuroinflammation plays a vital role in the etiology and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and multiple sclerosis. The neuroprotective role of androgens, including testosterone
Lei Yang, Renyuan Zhou, Y. Tong, Pengfei Chen, Yu Shen, S. Miao, Xiaoqiang Liu   +6 more
semanticscholar   +1 more source

Neuroprotection in glaucoma

Journal of Ophthalmic and Vision Research, 2016
Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC) loss and visual field defects. It is known that in some glaucoma patients, death of RGCs continues despite intraocular pressure (IOP) reduction. Neuroprotection in the field of glaucoma is defined as any treatment, independent of IOP reduction, which prevents RGC ...
Azadeh Doozandeh, Shahin Yazdani
openaire   +3 more sources

Nanodelivery of oxiracetam enhances memory, functional recovery and induces neuroprotection following concussive head injury

, 2021
Military personnel are the most susceptible to concussive head injury (CHI) caused by explosion, blast or missile or blunt head trauma. Mild to moderate CHI could induce lifetime functional and cognitive disturbances causing significant decrease in ...
Nozari, Ala, Preeti K. Menon, Castellani, Rudy J., Rudy J. Castellani, Menon, Preeti K.,, Aruna Sharma, Wang, Zhenguo, Lars Wiklund, Muresanu, Dafin F., Lianyuan Feng, Lafuente, José Vicente, Patnaik, Ranjana, Vicente Lafuente, José, Seaab Sahib, Sharma, Hari Shanker, Sahib, Seaab, Niu, Feng, Buzoianu, Anca D., Sharma, Aruna,, Ala Nozari, Ranjana Patnaik, Feng Niu, Dafin F. Muresanu, Sharma, Aruna, Menon, Preeti K., Wiklund, Lars, Hari Shanker Sharma, Feng, Lianyuan, Z. Ryan Tian, Tian, Z. Ryan, Wiklund, Lars,, Sharma, Hari Shanker,, Anca D. Buzoianu, José Vicente Lafuente, Zhenguo Wang   +34 more
core   +1 more source

Polyphenols from Food and Natural Products: Neuroprotection and Safety

Antioxidants, 2020
Polyphenols are naturally occurring micronutrients that are present in many food sources. Besides being potent antioxidants, these molecules may also possess anti-inflammatory properties.
Rui F. M. Silva, L. Pogačnik
semanticscholar   +1 more source

Neuroprotection by the Ketogenic Diet: Evidence and Controversies

Frontiers in Nutrition, 2021
The ketogenic diet (KD) is a high-fat low-carbohydrate diet that has been used for decades as a non-pharmacologic approach to treat metabolic disorders and refractory pediatric epilepsy.
S. Gough, A. Casella, K. Ortega, A. Hackam   +3 more
semanticscholar   +1 more source

Microglia and neuroprotection [PDF]

Journal of Neurochemistry, 2015
AbstractMicroglia were first identified over a century ago, but our knowledge about their ontogeny and functions has significantly expanded only recently. Microglia colonize the central nervous system (CNS) in utero and play essential roles in brain development.
Zhihong Chen, Bruce D. Trapp
openaire   +2 more sources

Concussive head injury exacerbates neuropathology of sleep deprivation : Superior neuroprotection by co-administration of TiO2-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells

, 2020
Sleep deprivation (SD) is common in military personnel engaged in combat operations leading to brain dysfunction. Military personnel during acute or chronic SD often prone to traumatic brain injury (TBI) indicating the possibility of further exacerbating
Patnaik, Ranjana,, Sharma, Aruna,, Bryukhovetskiy, Igor,, Tian, Z. Ryan,, Nozari, Ala,, Castellani, Rudy J.,, Vicente Lafuente, Jose,, Buzoianu, Anca D.,, Muresanu, Dafin F.,, Wiklund, Lars,, Sharma, Hari Shanker,, Sahib, Seaab,, Manzhulo, Igor,   +12 more
core   +1 more source

Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation

Translational Neurodegeneration, 2020
Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and oxidative stress, which are important factors contributing to the development of brain disease.
Luodan Yang, Hannah A Youngblood, Chongyun Wu, Quanguang Zhang   +3 more
semanticscholar   +1 more source

Neuroprotection in Brain Hypoxia

, 2019
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

core   +2 more sources