Results 51 to 60 of about 7,614 (192)

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, Volume 30, Issue 2, Page 168-175, April 2026.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye. [PDF]

, 2015
Accumulation of protein- and lipid-containing deposits external to the retinal pigment epithelium (RPE) is common in the aging eye, and has long been viewed as the hallmark of age-related macular degeneration (AMD).
Bird, AC, Boldt, K, Bundy, JG, Fearn, S, Flinn, JM, Jones, EA, Kortvely, E, Lanzirotti, A, Lengyel, I, McPhail, DS, Pauleikhoff, L, Ratu, SG, Reffatto, V, Thompson, RB, Ueffing, M   +14 more
core   +1 more source

Comparison of Presumed Geographic Retinal Dysplasia Between a Cavalier King Charles Spaniel and a Labrador Retriever

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Geographic retinal dysplasia is inherited in the Cavalier King Charles Spaniel. This detailed multimodal imaging description of an affected dog demonstrates that the presumed dysplastic retina area consists of a thickened retinal nerve fiber layer, similar to plaque‐like lesions previously reported in other breeds, such as the Labrador ...
Shaile Gehrke, Christine D. Harman, Amanda L. Jacobson, Gail McRae, András M. Komáromy   +4 more
wiley   +1 more source

L-DOPA is an endogenous ligand for OA1.

PLoS Biology, 2008
Albinism is a genetic defect characterized by a loss of pigmentation. The neurosensory retina, which is not pigmented, exhibits pathologic changes secondary to the loss of pigmentation in the retina pigment epithelium (RPE).
Vanessa M Lopez, Christina L Decatur, W Daniel Stamer, Ronald M Lynch, Brian S McKay   +4 more
doaj   +1 more source

A new surgical technique using steel suture for trans-scleral fixation of posterior chamber intraocular lenses

Indian Journal of Ophthalmology, 2013
Background: A new emerging complication of trans-scleral fixation of posterior chamber (PC) intraocular lens (IOL) with polypropylene suture is high rates of spontaneous dislocation of the IOL due to disintegration or breakage of suture.
Jagat Ram, Nishant Gupta, Manish Chaudhary, Neelam Verma   +3 more
doaj   +1 more source

Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. [PDF]

, 2013
Potassium (K(+)) ions released into brain extracellular space (ECS) during neuroexcitation are efficiently taken up by astrocytes. Deletion of astrocyte water channel aquaporin-4 (AQP4) in mice alters neuroexcitation by reducing ECS [K(+)] accumulation ...
Binder, Devin K, Jin, Byung-Ju, Verkman, AS, Zhang, Hua   +3 more
core   +2 more sources

Secretory autophagy and epithelial‐to‐mesenchymal transition in cadaveric AMD samples: Novel pathways in disease progression

Acta Ophthalmologica, Volume 104, Issue 2, Page 239-251, March 2026.
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran, Ali Koskela, Hanna Heloterä, Kai Kaarniranta   +3 more
wiley   +1 more source

Dietary and lifestyle risk factors associated with age-related macular degeneration: A hospital based study

Indian Journal of Ophthalmology, 2013
Aim : To establish the frequency, associations and risk factors for age-related macular degeneration (AMD) in hospital population of South India. Materials and Methods : In this cross-sectional hospital based study, 3549 subjects (2090 men and 1459 women)
Bhatiwada Nidhi, Bangera Sheshappa Mamatha, Chamrajnagar Anantharajiah Padmaprabhu, Prabhu Pallavi, Baskaran Vallikannan   +4 more
doaj   +1 more source

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function [PDF]

, 2018
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual ...
Angueyra, Juan M, Badiee, Mohsen, Kefalov, Vladimir J, Kinoshita, Junzo, Kiser, Philip D, Kolesnikov, Alexander V, Li, Wei, Palczewski, Krzysztof, Peachey, Neal S, Sharma, Aditya, Tochtrop, Gregory P, Zhang, Jianye   +11 more
core   +1 more source

Retinal Pigmented Epithelial Cells Cytotoxicity and Apoptosis through Activation of the Mitochondrial Intrinsic Pathway: Role of Indocyanine Green, Brilliant Blue and Implications for Chromovitrectomy [PDF]

, 2013
Purpose: To investigate the in vitro effect of four vital dyes on toxicity and apoptosis in a human retinal pigment epithelial (RPE) cell line.Methods: ARPE-19 cells were exposed to brilliant blue (BriB), methyl blue (MetB), acid violet (AcV) and ...
Cardoso, Emmerson Badaro, Costa, Elaine Fiod, Dib, Eduardo, Farah, Michel Eid, Maia, Mauricio, Marin-Castano, Maria E., Penha, Fernando Marcondes, Pons, Marianne, Rodrigues, Eduardo Buchele, Tenorio Barros, Nilana Meza   +9 more
core   +3 more sources