Results 51 to 60 of about 14,599 (210)

A Specific tRNA Half, 3'tiRNA‐GlyGCC, Regulates Hypoxic Pulmonary Artery Smooth Muscle Cell Proliferation via Myrf‐Mediated Endoplasmic Reticulum Stress

Cell Proliferation, EarlyView.
A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang, Xiaoyu Guan, Xiangrui Zhu, Yingying Hao, Ya Xu, Hao Yuan, Danni Gao, Hongxia Du, Jiayu Li, Weiwei Cao, Cui Ma, Xiaoying Wang   +11 more
wiley   +1 more source

Neurotensin activates orexin neurons.

, 2013
A, Whole cell current clamp recording of orexin neurons shows that neurotensin (100 nM) depolarized orexin neurons in the absence (top) or presence (bottom) of TTX (1 µM).
Seiji Shioda (204796), Natsuko Tsujino (169784), Masashi Yanagisawa (224823), Mari Hondo (204857), Haruaki Kageyama (404473), Michihiro Mieda (219471), Naoki Furutani (169799), Takeshi Sakurai (144574)   +7 more
core   +1 more source

Endometrial Epithelial Cell Apoptosis Is Inhibited by a ciR8073-miR181a-Neurotensis Pathway during Embryo Implantation

Molecular Therapy: Nucleic Acids, 2019
Development of the receptive endometrium (RE) from the pre-receptive endometrium (PE) is essential for embryo implantation, but its molecular mechanisms have not been fully understood. In this study, lncRNA-miRNA-mRNA and circRNA-miRNA-mRNA networks were
Lei Zhang, Xiaorui Liu, Sicheng Che, Jiuzeng Cui, Xingna Ma, Xiaopeng An, Binyun Cao, Yuxuan Song   +7 more
doaj   +1 more source

Intravenous Oxytocin Does Not Affect Glucose‐Regulating Hormones or Markers of Bone Turnover During Graded Glucose Infusion in Healthy Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Oxytocin has been proposed to exert glucose‐stabilising effects via modulation of pancreatic hormone secretion and to play a role in bone homeostasis. However, human data under controlled conditions are limited. We investigated the effects of intravenously infused oxytocin during a graded glucose infusion on glucose‐regulating hormones and
Vivian Kliim‐Hansen, Ida M. Gether, Aliya M. Thomas, Anne‐Marie Ellegaard, Miriam G. Pedersen, Jens J. Holst, Bolette Hartmann, Filip K. Knop, Lærke S. Gasbjerg, Asger B. Lund   +9 more
wiley   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Pioglitazone abolishes cognition impairments as well as BDNF and neurotensin disturbances in a rat model of autism

Biology Open, 2019
We have shown that exposure of rats to lipopolysaccharide (LPS) during gestation induces autistic-like behaviors in juvenile offspring and pioglitazone post treatment corrects social and communication deficits.
Thiago B. Kirsten, Renato C. Casarin, Maria M. Bernardi, Luciano F. Felicio   +3 more
doaj   +1 more source

Key-Protease Inhibition Regimens Promote Tumor Targeting of Neurotensin Radioligands

Pharmaceutics, 2020
Neurotensin subtype 1 receptors (NTS1R) represent attractive molecular targets for directing radiolabeled neurotensin (NT) analogs to tumor lesions for diagnostic and therapeutic purposes.
Panagiotis Kanellopoulos, Aikaterini Kaloudi, Marion de Jong, Eric P. Krenning, Berthold A. Nock, Theodosia Maina   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, Volume 600, Issue 17, Page 2437-2450, September 2026.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Neurotensin receptors in human meningiomas

, 1991
We have investigated the presence of neurotensin receptors in human meningiomas by in vitro binding autoradiography. Ten of the 12 meningiomas tested displayed specific [3H}neurotensin binding.
Levivier, M., Cadet, J.L., Przedborski, S., Levivier, Marc, Przedborski, Serge, Cadet, Jean   +5 more
core   +1 more source

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, Volume 5, Issue 3, Page 769-776, September 2026.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source