Results 1 to 10 of about 95,554 (282)
Electrical or magnetic nerve stimulation enhance the BoNT/A-mediated muscle paralysis [PDF]
Journal of NeuroEngineering and RehabilitationBackground Botulinum toxin type A (BoNT/A) is first-line treatment for muscle spasticity but the dose can be limited by side effects depending on the treated muscle mass and location.
Stefanie Honndorf, Klaus Fink
doaj +2 more sources
Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
core +17 more sources
Retroform Cervical Dystonia: Target Muscle Selection and Efficacy of Botulinum Toxin Injection
Frontiers in Neurology, 2022 IntroductionRetroform cervical dystonia (RCD), which includes retrocaput and retrocollis, is a rare form of cervical dystonia. Few reports have been published on RCD.
Yaowen Hu +8 more
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Botulinum Neurotoxin Type A Directly Affects Sebocytes and Modulates Oleic Acid-Induced Lipogenesis
Toxins, 2022 Excess sebum (seborrhea) results in oily skin and is associated with large pore size and acne. Studies in healthy, seborrheic volunteers have reported that intradermal injection of commercial preparations of botulinum neurotoxin type A (BoNT/A ...
Karen Brami-Cherrier +5 more
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Correction: Steele et al. Misincorporation Proteomics Technologies: A Review. Proteomes 2021, 9, 2
Proteomes, 2022 In the original publication, there was a mistake in Table 2 as published [...]
Joel R. Steele +6 more
doaj +1 more source
Scientific Reports, 2021 Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis.
Nicholas G. James +7 more
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Misincorporation Proteomics Technologies: A Review
Proteomes, 2021 Proteinopathies are diseases caused by factors that affect proteoform conformation. As such, a prevalent hypothesis is that the misincorporation of noncanonical amino acids into a proteoform results in detrimental structures.
Joel R. Steele +6 more
doaj +1 more source
Kinect-based objective evaluation of bradykinesia in patients with Parkinson's disease
Digital Health, 2023 Objective To quantify bradykinesia in Parkinson's disease (PD) with a Kinect depth camera-based motion analysis system and to compare PD and healthy control (HC) subjects. Methods Fifty PD patients and twenty-five HCs were recruited.
Zhuang Wu +15 more
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Frontiers in Aging Neuroscience, 2022 BackgroundExercise plays an essential role in improving motor symptoms in Parkinson’s disease (PD), but the underlying mechanism in the central nervous system remains unclear.MethodsMotor ability was observed after 12-week treadmill exercise on a 1 ...
Weifang Tong +12 more
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npj Parkinson's Disease, 2022 Postural abnormalities are common disabling motor complications affecting patients with Parkinson’s disease (PD). We proposed a summary index for postural abnormalities (IPA) based on Kinect depth camera and explored the clinical value of this indicator.
Ronghua Hong +13 more
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