Results 21 to 30 of about 132,798 (382)

Prediction of presynaptic and postsynaptic neurotoxins based on feature extraction

Mathematical Biosciences and Engineering, 2021
A neurotoxin is essentially a protein that mainly acts on the nervous system; it has a selective toxic effect on the central nervous system and neuromuscular nodes, can cause muscle paralysis and respiratory paralysis, and has strong lethality. According
Wen Zhu, Yuxin Guo, Quan Zou
doaj   +1 more source

Incobotulinum Toxin Type A for Treatment of Ultraviolet-B-Induced Hyperpigmentation: A Prospective, Randomized, Controlled Trial

Toxins, 2022
Incobotulinum toxin A (IncoBoNT-A) is effective in preventing ultraviolet B (UVB)-induced hyperpigmentation. This prospective, randomized, controlled study aimed to evaluate the effect of IncoBoNT-A on the treatment of UVB-induced hyperpigmentation in 15
Vasanop Vachiramon, Tanaporn Anuntrangsee, Pasita Palakornkitti, Natthachat Jurairattanaporn, Sarawin Harnchoowong   +4 more
doaj   +1 more source

Recombinant botulinum neurotoxin serotype A1 in vivo characterization

Pharmacology Research & Perspectives, 2021
Clinically used botulinum neurotoxins (BoNTs) are natural products of Clostridium botulinum. A novel, recombinant BoNT type A1 (rBoNT/A1; IPN10260) has been synthesized using the native amino acid sequence expressed in Escherichia coli and has previously
Cindy Périer, Vincent Martin, Sylvie Cornet, Christine Favre‐Guilmard, Marie‐Noelle Rocher, Julien Bindler, Stéphanie Wagner, Emile Andriambeloson, Brian B. Rudkin, Rudy Marty, Alban Vignaud, Matthew Beard, Stephane Lezmi, Mikhail Kalinichev   +13 more
doaj   +1 more source

Behavioral Tests in Neurotoxin-Induced Animal Models of Parkinson’s Disease

Antioxidants, 2020
Currently, neurodegenerative diseases are a major cause of disability around the world. Parkinson’s disease (PD) is the second-leading cause of neurodegenerative disorder after Alzheimer’s disease.
Maruthi Prasad E, Shih-Ya Hung
semanticscholar   +1 more source

Development of Antibody Detection ELISA Based on Immunoreactive Toxins and Toxin-Derived Peptides to Evaluate the Neutralization Potency of Equine Plasma against Naja atra in Taiwan

Toxins, 2021
Naja atra, also known as Taiwanese cobra, is one of the most prevalent venomous snakes in Taiwan. Clinically, freeze-dried neurotoxic antivenom (FNAV) produced from horses by Taiwan Centers for Disease Control (CDC) has been the only approved treatment ...
Chien-Chun Liu, Yung-Chin Hsiao, Lichieh Julie Chu, Po-Jung Wang, Chien-Hsin Liu, Wen-Chin Hsieh, Jau-Song Yu   +6 more
doaj   +1 more source

Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses [PDF]

, 2006
Synaptic vesicle (SV) exocytosis mediating neurotransmitter release occurs spontaneously at low intraterminal calcium concentrations and is stimulated by a rise in intracellular calcium.
A. Scheuber, Blagoveshchenskaya, Dell'Angelica, Fa  ndez, G. Raposo, Goda, Guti  rrez, Hayashi, J.-C. Poncer, Kamiya, Kantheti, L. Danglot, Li, Lopantsev, Musleh, Muzerelle, R. Rudge, Rizzoli, Rosenmund, Sakaba, Schoch, Sj  str  m, Stobrawa, Stoppini, Sudhof, Sugita, Sugita, T. Binz, T. Galli, Takei, Vogt, Woodhall, Xu   +32 more
core   +6 more sources

The binding of botulinum neurotoxins to different peripheral neurons [PDF]

, 2017
Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core   +1 more source

Safety and patient satisfaction of abobotulinumtoxinA for aesthetic use. A systematic review [PDF]

, 2017
A systematic review of the published literature (from January 2000 to January 2016) to ascertain the safety of, and patient satisfaction with, the aesthetic use of abobotulinumtoxinA was conducted.
Cohen, Joel L, Scuderi, Nicolo'
core   +1 more source

Botulinum Neurotoxin for the Treatment of Neuropathic Pain

Frontiers in Neurology, 2020
Botulinum neurotoxin is widely used for the treatment of central and peripherical neurological conditions. Initially used to treat strabismus, over the years its use has been expanded also to spasticity and other neurological disorders.
G. Egeo, L. Fofi, P. Barbanti
semanticscholar   +1 more source

Compensatory Masseteric Bulging: A Novel Observation and Its Implications for Botulinum Neurotoxin Injection Techniques. [PDF]

J Cosmet Dermatol
Yi KH, Wan J.
europepmc   +3 more sources