Results 41 to 50 of about 132,798 (382)

Evaluation of a Commercial Enzyme Linked Immunosorbent Assay (ELISA) for the Determination of the Neurotoxin BMAA in Surface Waters [PDF]

, 2013
The neurotoxin ß-N-methylamino-L-alanine (BMAA) is suspected to play a role in Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. Because BMAA seems to be produced by cyanobacteria, surface waters are screened for BMAA.
A Vega, AS Chiu, EJ Faassen, Elisabeth J. Faassen, H Zahradníčková, J Rosén, JS Metcalf, M Esterhuizen, Miquel Lürling, PA Cox, PA Cox, R Dai, RC Cervantes Cianca, S Jonasson, SA Cohen, T Krüger, Tilmann Harder, WB Glover, Wendy Beekman, WG Bradley, Z Spáčil   +20 more
core   +5 more sources

The Effect of Australian and Asian Commercial Antivenoms in Reversing the Post-Synaptic Neurotoxicity of O. hannah, N. naja and N. kaouthia Venoms In Vitro

Toxins, 2022
Despite antivenoms being the only established specific treatment for neuromuscular paralysis arising from snake envenoming, their ability to reverse the post-synaptic neurotoxicity in snake envenoming is poorly understood.
Tam M. Huynh, Wayne C. Hodgson, Geoffrey K. Isbister, Anjana Silva   +3 more
doaj   +1 more source

Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom

Science, 2018
How algae turn tides toxic Algal blooms can devastate marine mammal communities through the production of neurotoxins that accumulate within the food web. Brunson et al.
J. K. Brunson, J. K. Brunson, Shaun M. K. McKinnie, J. R. Chekan, J. McCrow, Z. Miles, Erin M. Bertrand, Erin M. Bertrand, Vincent A. Bielinski, H. Luhavaya, M. Oborník, G. Smith, D. Hutchins, A. Allen, A. Allen, B. Moore, B. Moore   +16 more
semanticscholar   +1 more source

The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. [PDF]

, 2016
Cell polarity and precise subcellular protein localization are pivotal to neuronal function. The SNARE machinery underlies intracellular membrane fusion events, but its role in neuronal polarity and selective protein targeting remain unclear.
Albertolle, Mary E, Banna, Chris D, Low, Seng Hui, Radeke, Carolyn M, Sharma, Nikunj, Soo Hoo, Linda, Vandenberg, Carol A, Weimbs, Thomas   +7 more
core   +1 more source

Neurotoxin-Induced Animal Models of Parkinson Disease: Pathogenic Mechanism and Assessment

ASN Neuro, 2018
Parkinson disease (PD) is the second most common neurodegenerative movement disorder. Pharmacological animal models are invaluable tools to study the pathological mechanisms of PD.
Xiansi Zeng, Wenshuo Geng, Jinjing Jia
semanticscholar   +1 more source

Peptide Toxins in Solitary Wasp Venoms

Toxins, 2016
Solitary wasps paralyze insects or spiders with stinging venom and feed the paralyzed preys to their larva. Accordingly, the venoms should contain a variety of constituents acting on nervous systems.
Katsuhiro Konno, Kohei Kazuma, Ken-ichi Nihei   +2 more
doaj   +1 more source

Cholinergic innervation is necessary to shift reward timing activity in rodent visual cortex [PDF]

, 2011
While the biological analogue of prediction error has been well characterized in the midbrain dopaminergic system, the possibility of other neuromodulatory systems acting as global reinforcers is a topic of much debate.
Emma Roach, Marshall Hussain Shuler
core   +2 more sources

Centrally mediated late motor recovery after botulinum toxin injection: Case reports and a review of current evidence

Journal of Rehabilitation Medicine, 2017
Objective: Botulinum neurotoxin is commonly utilized in neurorehabilitation as a treatment for focal spasticity. Clinical experience has yielded observations of late motor recovery after intramuscular injection of botulinum neurotoxin, that are not ...
Manuel F. Mas, Sheng Li, Gerard E. Francisco   +2 more
doaj   +1 more source

Short Toxin-like Proteins Attack the Defense Line of Innate Immunity

Toxins, 2013
ClanTox (classifier of animal toxins) was developed for identifying toxin-like candidates from complete proteomes. Searching mammalian proteomes for short toxin-like proteins (coined TOLIPs) revealed a number of overlooked secreted short proteins with an
Tsiona Eliyahu, Michal Linial, Yitshak Tirosh, Dan Ofer   +3 more
doaj   +1 more source

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]

, 1996
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
Bahn, R. S., Gleich, G. J., Goellner, J. R., Hay, I. D., Heufelder, Armin E.   +4 more
core   +1 more source