Results 41 to 50 of about 105,668 (383)

Distribution of Tetrodotoxin in the New Zealand Clam, Paphies australis, Established Using Immunohistochemistry and Liquid Chromatography-Tandem Quadrupole Mass Spectrometry

Toxins, 2018
Tetrodotoxin (TTX) is one of the most potent neurotoxins known. It was originally thought to only occur in puffer fish but has now been identified in twelve different classes of freshwater and marine organisms, including bivalves.
Laura Biessy, Kirsty F. Smith, Michael J. Boundy, Stephen C. Webb, Ian Hawes, Susanna A. Wood   +5 more
doaj   +1 more source

β-n-oxalyl-l-α, β -diaminopropionic acid (β -odap) content in lathyrus sativus: The integration of nitrogen and sulfur metabolism through β -cyanoalanine synthase [PDF]

, 2017
Grass pea (Lathyrus sativus L.) is an important legume crop grown mainly in South Asia and Sub-Saharan Africa. This underutilized legume can withstand harsh environmental conditions including drought and flooding.
Chen, Peng, Jez, Joseph M, Krishnan, Hari B, Liu, Fengjuan, Xu, Quanle   +4 more
core   +3 more sources

Neurotoxin-Induced Animal Models of Parkinson Disease: Pathogenic Mechanism and Assessment

ASN Neuro, 2018
Parkinson disease (PD) is the second most common neurodegenerative movement disorder. Pharmacological animal models are invaluable tools to study the pathological mechanisms of PD.
Xiansi Zeng, Wenshuo Geng, Jinjing Jia
semanticscholar   +1 more source

An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management

Marine Drugs, 2017
Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world. It causes substantial human health, social, and economic impacts.
Melissa A. Friedman, Mercedes Fernandez, Lorraine C. Backer, Robert W. Dickey, Jeffrey Bernstein, Kathleen Schrank, Steven Kibler, Wendy Stephan, Matthew O. Gribble, Paul Bienfang, Robert E. Bowen, Stacey Degrasse, Harold A. Flores Quintana, Christopher R. Loeffler, Richard Weisman, Donna Blythe, Elisa Berdalet, Ram Ayyar, Danielle Clarkson-Townsend, Karen Swajian, Ronald Benner, Tom Brewer, Lora E. Fleming   +22 more
doaj   +1 more source

Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom

Science, 2018
How algae turn tides toxic Algal blooms can devastate marine mammal communities through the production of neurotoxins that accumulate within the food web. Brunson et al.
J. K. Brunson, J. K. Brunson, Shaun M. K. McKinnie, J. R. Chekan, J. McCrow, Z. Miles, Erin M. Bertrand, Erin M. Bertrand, Vincent A. Bielinski, H. Luhavaya, M. Oborník, G. Smith, D. Hutchins, A. Allen, A. Allen, B. Moore, B. Moore   +16 more
semanticscholar   +1 more source

Botulinum and Tetanus Neurotoxins [PDF]

Annual Review of Biochemistry, 2019
Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as therapeutic toxins. They contain three functional domains responsible for receptor-binding, membrane translocation, and proteolytic cleavage of host proteins required for synaptic ...
Min Dong, Min Dong, Geoffrey Masuyer, Pål Stenmark   +3 more
openaire   +4 more sources

Overlooked Short Toxin-Like Proteins: A Shortcut to Drug Design

Toxins, 2017
Short stable peptides have huge potential for novel therapies and biosimilars. Cysteine-rich short proteins are characterized by multiple disulfide bridges in a compact structure.
Michal Linial, Nadav Rappoport, Dan Ofer
doaj   +1 more source

Resistance to cosmetic botulinum toxin A: A 15-patient case series across 12 sites [PDF]

JAAD International
Carlos G. Wambier, MD, PhD, Fatima N. Mirza, MD, MPH, Sarah P.F. Wambier, MD, PhD, Vince Bertucci, MD, Jean Carruthers, MD, Joely Kaufman, MD, John Martin, MD, J. Barton Sterling, MD, Flávia Brasileiro, MD, Carolina Marçon, MD, MSc, Allison J. Brown, MD, Miranda Rosenberg, MD, Lilia R.S. Guadanhim, MD, PhD, Doris Hexsel, MD   +13 more
doaj   +2 more sources

Evaluation of a Commercial Enzyme Linked Immunosorbent Assay (ELISA) for the Determination of the Neurotoxin BMAA in Surface Waters [PDF]

, 2013
The neurotoxin ß-N-methylamino-L-alanine (BMAA) is suspected to play a role in Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. Because BMAA seems to be produced by cyanobacteria, surface waters are screened for BMAA.
A Vega, AS Chiu, EJ Faassen, Elisabeth J. Faassen, H Zahradníčková, J Rosén, JS Metcalf, M Esterhuizen, Miquel Lürling, PA Cox, PA Cox, R Dai, RC Cervantes Cianca, S Jonasson, SA Cohen, T Krüger, Tilmann Harder, WB Glover, Wendy Beekman, WG Bradley, Z Spáčil   +20 more
core   +8 more sources

Centrally mediated late motor recovery after botulinum toxin injection: Case reports and a review of current evidence

Journal of Rehabilitation Medicine, 2017
Objective: Botulinum neurotoxin is commonly utilized in neurorehabilitation as a treatment for focal spasticity. Clinical experience has yielded observations of late motor recovery after intramuscular injection of botulinum neurotoxin, that are not ...
Manuel F. Mas, Sheng Li, Gerard E. Francisco   +2 more
doaj   +1 more source