Results 201 to 210 of about 195,340 (251)
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Dendritic Release of Neurotransmitters
Comprehensive Physiology, 2017ABSTRACT Release of neuroactive substances by exocytosis from dendrites is surprisingly widespread and is not confined to a particular class of transmitters: it occurs in multiple brain regions, and includes a range of neuropeptides, classical neurotransmitters, and signaling molecules, such as nitric oxide ...
Mike, Ludwig +4 more
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Uptake and Release of Neurotransmitters
Current Protocols in Neuroscience, 1998AbstractThe availability of clonal cell lines for norepinephrine, dopamine, and serotonin transporters allows the characterization of drug interactions with transporter recognition sites using radioligands, as well as the characterization of drug effects on selective transporter‐mediated uptake and release of substrate. In addition to clonal cell lines,
A, Janowsky, K, Neve, A J, Eshleman
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The bioenergetics of neurotransmitter release
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1991Synaptosomal energetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 A. Na + and K+-circuits across the synaptosomal plasma membrane . . . . . . . . . . . . . . . . . . . . . 246 B. The thermodynamics of Na + coupled transmitter carriers . . . . . . . . . . . . . . . . . . . . . . . . . 248
H T, McMahon, D G, Nicholls
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Mechanisms of Neurotransmitter Release
International Review of Neurobiology, 1999Publisher Summary This chapter focuses on the mechanism of neurotransmitter release. The primary form of intercellular communication within the nervous system is mediated by chemical transmission at synapses. Upon propagation of an action potential into the nerve terminal, there is an influx of Ca2+ through voltage-activated Ca2+ channels, which ...
J T, Littleton, L, Pallanck, B, Ganetzky
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Annual Review of Neuroscience, 1996
Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Storage and release of neurotransmitters
Cell, 1993Because synaptic vesicles and secretory granules are simple in composition and easy to purify, many of their protein components have been identified and often sequenced. Attempts are underway to link the small number of membrane proteins to the small number of functions the vesicles perform.
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2008
Neurons send out a multitude of chemical signals, called neurotransmitters, to communicate between neurons in brain, and between neurons and target cells in the periphery. The most important of these communication processes is synaptic transmission, which accounts for the ability of the brain to rapidly process information, and which is characterized ...
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Neurons send out a multitude of chemical signals, called neurotransmitters, to communicate between neurons in brain, and between neurons and target cells in the periphery. The most important of these communication processes is synaptic transmission, which accounts for the ability of the brain to rapidly process information, and which is characterized ...
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Neurotransmitter release at fast synapses
The Journal of Membrane Biology, 1994As stated at the beginning of this review, the mechanism of neurotransmitter release is not yet known. Keeping this in mind, we shall, nevertheless, attempt to speculate and outline a possible scenario of events as it emerges from the foregoing discussion.
H, Parnas, I, Parnas
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Carrier-mediated release of neurotransmitters
Trends in Neurosciences, 1993There is growing evidence that neurotransmitters can be released not only by exocytosis but also through the membrane carriers responsible for transmitter reuptake. Giulio Levi and Maurizio Raiteri review the in vitro and in vivo evidence supporting the existence of a carrier-mediated release for different classes of transmitters.
G, Levi, M, Raiteri
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Neurotransmitter release at rapid synapses
Biochimie, 2000The classical concept of the vesicular hypothesis for acetylcholine (ACh) release, one quantum resulting from exocytosis of one vesicle, is becoming more complicated than initially thought. 1) synaptic vesicles do contain ACh, but the cytoplasmic pool of ACh is the first to be used and renewed on stimulation.
Dunant Y, Israël M
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