Results 1 to 10 of about 12,876,613 (271)

Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]

open access: bronze, 2001
Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P   +3 more
core   +3 more sources

The impact of brain-derived neurotrophic factor gene polymorphisms on post-stroke naming in aphasia. [PDF]

open access: yesPLoS ONE
Post-stroke aphasia, or language deficits after stroke, afflicts 20-30% of survivors and often persists into the chronic phase. The protein brain-derived neurotrophic factor has been identified as important for neuroplasticity, and is regulated by the ...
Matilda Randighieri   +8 more
doaj   +2 more sources

Melatonin: A Neurotrophic Factor?

open access: yesMolecules, 2022
Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal environment with the photoperiod. It is synthesized in the pineal gland and greatly depends on the endogenous circadian clock located in the suprachiasmatic nucleus and ...
Armida Miranda-Riestra   +5 more
doaj   +1 more source

Neurotrophic basis to the pathogenesis of depression and phytotherapy

open access: yesFrontiers in Pharmacology, 2023
Depression is a major neuropsychiatric disease that considerably impacts individuals’ psychosocial function and life quality. Neurotrophic factors are now connected to the pathogenesis of depression, while the definitive neurotrophic basis remains ...
Huiqin Wang   +6 more
doaj   +1 more source

FEATURES OF METABOLISM AND THE POTENTIAL ROLE OF NEUROTROPHIC FACTORS OF THE BRAIN IN THE REHABILITATION PROCESS

open access: yesSiberian Journal of Life Sciences and Agriculture, 2023
Understanding the metabolic pathways of regulation and interaction of neurotrophic factors is interesting from the point of view of discussing neurotrophic factors as biological markers reflecting the dynamics and effectiveness of the rehabilitation ...
Elizaveta S. Ageeva   +6 more
doaj   +1 more source

Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone

open access: yesNeural Regeneration Research, 2023
The trigeminal root entry zone is the zone at which the myelination switches from peripheral Schwann cells to central oligodendrocytes. Its special anatomical and physiological structure renders it susceptible to nerve injury.
Madeha Ishag Adam   +8 more
doaj   +1 more source

Ciliary neurotrophic factor [PDF]

open access: yesJournal of Neurobiology, 1994
AbstractCiliary neurotrophic factor (CNTF) was first identified and partially purified from embryonic chick eye tissues. Subsequently, it was shown that CNTF is also present in large amounts in sciatic nerves of adult rats and rabbits, which led to its final purification and cloning. CNTF is not secreted by the classical secretory pathway involving the
Sendtner, Michael   +4 more
openaire   +3 more sources

Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease

open access: yesNeural Regeneration Research, 2023
Studies have found that the absence of glial cell line-derived neurotrophic factor may be the primary risk factor for Parkinson’s disease. However, there have not been any studies conducted on the potential relationship between glial cell line-derived ...
Chuan-Xi Tang   +16 more
doaj   +1 more source

S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk. [PDF]

open access: yesPLoS ONE, 2011
Human milk contains a wide variety of nutrients that contribute to the fulfillment of its functions, which include the regulation of newborn development.
Ruisong Li   +3 more
doaj   +1 more source

GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries

open access: yesNeural Regeneration Research, 2022
Peripheral nerve injuries commonly occur due to trauma, like a traffic accident. Peripheral nerves get severed, causing motor neuron death and potential muscle atrophy.
Alberto F Cintron-Colon   +3 more
doaj   +1 more source

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