Results 11 to 20 of about 13,403,812 (361)

Neurotrophic factors and corneal nerve regeneration [PDF]

Neural Regeneration Research, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Marta Sacchetti, Alessandro Lambiase
doaj   +5 more sources

The Role of Metals in the Neuroregenerative Action of BDNF, GDNF, NGF and Other Neurotrophic Factors

Biomolecules, 2022
Mature neurotrophic factors and their propeptides play key roles ranging from the regulation of neuronal growth and differentiation to prominent participation in neuronal survival and recovery after injury.
Vincenzo Giuseppe Nicoletti, Krisztián Pajer, Damiano Calcagno, Gholam Pajenda, Antal Nógrádi   +4 more
doaj   +2 more sources

Neurotrophic factors in multiple sclerosis [PDF]

Frontiers in Immunology
Smoldering inflammation and neurodegeneration, primarily driven by intraparenchymal immune cell activation and glial dysfunction, remains a major therapeutic challenge in Multiple Sclerosis (MS) and contributes largely to disability progression.
Fabian Güner, Fabian Güner, Veit Rothhammer, Veit Rothhammer   +3 more
doaj   +2 more sources

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

Neural Regeneration Research, 2017
Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio, Anne Suely Savall, Maria Eduarda Ziani Gutierrez, Simone Pinton   +3 more
doaj   +2 more sources

Neurotrophic Factors in Health and Disease [PDF]

Cells, 2022
Neurotrophic factors, including neurotrophins and neuropeptides, are secreted proteins that regulate the survival, development, and physiological functions of neurons in both the central and peripheral nervous systems [...]
Cinzia Severini
doaj   +2 more sources

Neurotrophic factors and their effects in the treatment of multiple sclerosis

Advanced Biomedical Research, 2015
Neurotrophins are small molecules of polypeptides, which include nerve growth factor (NGF) family, glial cell line-derived neurotrophic factor (GDNF) family ligands, and neuropoietic cytokines. These factors have an important role in neural regeneration,
Shahnaz Razavi, Ghasemi Nazem, Mohammad Mardani, Ebrahim Esfandiari, Hossein Salehi, Sayyed Hamid Zarkesh Esfahani   +5 more
doaj   +2 more sources

Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?

Neurobiology of Disease, 2017
The therapeutic potential of neurotrophic factors has been recognized for decades, with clinical trials in human neurodegenerative diseases extending back at least 25 years.
Raymond T. Bartus, Eugene M. Johnson, Jr.   +1 more
doaj   +2 more sources

Inflammatory Biomarkers and Neurotrophic Factors in Preterm Newborns as Predictors of Motor Development: A Systematic Review [PDF]

Pediatric Reports
Background/Objectives: Preterm newborns (NBs) are at increased risk of motor developmental impairments. Evidence on inflammatory and neurotrophic biomarkers measured in the neonatal period as predictors of motor outcomes is scarce and heterogeneous. This
Letícia Silva Gabriel, Vicente Donisete Ferreira Júnior, Marina Ornelas Anastácia Pereira, Dayanne Gabriela de Melo Marques, Virgínia Mendes Russo Vallejos, Melina Barros-Pinheiro   +5 more
doaj   +2 more sources

Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research

Neural Plasticity, 2022
Ischemic stroke and traumatic brain injury (TBI) are among the leading causes of death and disability worldwide with impairments ranging from mild to severe.
Serena-Kaye Sims, Brynna Wilken-Resman, Crystal J. Smith, Ashley Mitchell, Lilly McGonegal, Catrina Sims-Robinson   +5 more
doaj   +2 more sources

Priming Canine Adipose Tissue-Derived Mesenchymal Stem Cells with CBD-Rich Cannabis Extract Modulates Neurotrophic Factors Expression Profile. [PDF]

Vet Sci
Perino VS, Ferreira LVO, Kamura BDC, Chimenes ND, Olbera AVG, Pereira TT, Braz AMM, Golim MA, Carvalho M, Amorim RM.   +9 more
europepmc   +3 more sources