Results 21 to 30 of about 176,376 (142)
Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease
The involvement of the changed expression/function of neurotrophic factors in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD), has been suggested.
Tadahiro Numakawa, Ryutaro Kajihara
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Increasing evidence suggests that abnormal regulation of neurotrophic factors is involved in the etiology and pathogenesis of Autism Spectrum Disorder (ASD).
Shu-Han Liu+3 more
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Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio+3 more
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Ischemic stroke and traumatic brain injury (TBI) are among the leading causes of death and disability worldwide with impairments ranging from mild to severe.
Serena-Kaye Sims+5 more
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Neurotrophic factor-based pharmacological approaches in neurological disorders
Aging is a physiological event dependent on multiple pathways that are linked to lifespan and processes leading to cognitive decline. This process represents the major risk factor for aging-related diseases such as Alzheimer’s disease, Parkinson’s ...
Margherita Alfonsetti+2 more
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Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth [PDF]
Designing synthetic microenvironments for cellular investigations is a very active area of research at the crossroads of cell biology and materials science. The present work describes the design and functionalization of a three-dimensional (3D) culture support dedicated to the study of neurite outgrowth from neural cells.
arxiv +1 more source
[INLINE:1] The introduction of neurotrophic factors into injured peripheral nerve sites is beneficial to peripheral nerve regeneration. However, neurotrophic factors are rapidly degraded in vivo and obstruct axonal regeneration when used at a ...
Ci Li+7 more
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Neurotrophic factors in tension-type headache
Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH).
Renan B. Domingues+3 more
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Neurotrophic factors and their effects in the treatment of multiple sclerosis
Neurotrophins are small molecules of polypeptides, which include nerve growth factor (NGF) family, glial cell line-derived neurotrophic factor (GDNF) family ligands, and neuropoietic cytokines. These factors have an important role in neural regeneration,
Shahnaz Razavi+5 more
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Neurotrophic Effects of Intermittent Fasting, Calorie Restriction and Exercise: A Review and Annotated Bibliography [PDF]
In the last decades, important progress has been achieved in the understanding of the neurotrophic effects of intermittent fasting (IF), caloric restriction (CR) and exercise. Improved neuroprotection, synaptic plasticity and adult neurogenesis (NSPAN) are essential examples of these neurotrophic effects. The importance in this respect of the metabolic
arxiv