Results 21 to 30 of about 12,269,638 (359)
Melatonin: A Neurotrophic Factor?
Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal environment with the photoperiod. It is synthesized in the pineal gland and greatly depends on the endogenous circadian clock located in the suprachiasmatic nucleus and the retina’s exposure to different light intensities.
Armida Miranda-Riestra+5 more
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Antidepressant-like effects of trophic factor receptor signaling
A significant body of research has demonstrated that antidepressants regulate neurotrophic factors and that neurotrophins themselves are capable of independently producing antidepressant-like effects.
Monica Sathyanesan+3 more
doaj +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo+11 more
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The Role of BDNF on Neural Plasticity in Depression
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that depression is closely related to the abnormal neural plasticity processes occurring in the prefrontal cortex and limbic system such as the hippocampus and amygdala ...
Tao Yang+7 more
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Neurotrophic Factors and Their Receptors [PDF]
Several new members of the nerve growth factor family of neurotrophins, which comprises nerve growth factor itself, brain-derived neurotrophic factor and neurotrophins-3, -4 (also known as neurotrophin-5) and -6, have been isolated in recent years.
Vimal Parkash
openalex +4 more sources
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza+3 more
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MANF: A New Player in the Control of Energy Homeostasis, and Beyond
All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
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Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease
The involvement of the changed expression/function of neurotrophic factors in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD), has been suggested.
Tadahiro Numakawa, Ryutaro Kajihara
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Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]
Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P+3 more
core +1 more source
Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression
Depression is a major health problem with a high prevalence and a heavy socioeconomic burden in western societies. It is associated with atrophy and impaired functioning of cortico-limbic regions involved in mood and emotion regulation.
M. Levy+5 more
semanticscholar +1 more source