Results 21 to 30 of about 12,648,804 (372)
The Role of BDNF on Neural Plasticity in Depression
Frontiers in Cellular Neuroscience, 2020 Using behavioral, pharmacological, and molecular methods, lots of studies reveal that depression is closely related to the abnormal neural plasticity processes occurring in the prefrontal cortex and limbic system such as the hippocampus and amygdala ...
Tao Yang +7 more
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Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
, 2017 The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo +11 more
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MANF: A New Player in the Control of Energy Homeostasis, and Beyond
Frontiers in Physiology, 2018 All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
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Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]
, 1989 Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A. +5 more
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Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
, 2020 Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
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Materials & Design, 2022 The combination of biological scaffold and neural stem cells (NSCs) is a promising treatment strategy for spinal cord injury (SCI). But adverse niche at injures spinal cord severe hamper the transplanted NSCs to preferentially differentiate neurons.
Shuo Liu +5 more
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Involvement of ras p2I in Neurotrophin-induced Response of Sensory, but Not Sympathetic Neurons [PDF]
, 1993 Little is known about the signal transduction mechanisms involved in the response to neurotrophins and other neurotrophic factors in neurons, beyond the activation of the tyrosine kinase activity of the neurotrophin receptors belonging to the trk family.
Barde, Y. A. +4 more
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Scientific Reports, 2021 Increasing evidence suggests that abnormal regulation of neurotrophic factors is involved in the etiology and pathogenesis of Autism Spectrum Disorder (ASD).
Shu-Han Liu +3 more
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Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease
Life, 2023 The involvement of the changed expression/function of neurotrophic factors in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD), has been suggested.
Tadahiro Numakawa, Ryutaro Kajihara
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Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]
, 2001 Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P +3 more
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