Results 51 to 60 of about 438,037 (298)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Curvature of NCNTs induced selectivity of CO2 electroreduction into CO

open access: yesCarbon Neutralization, 2022
Nitrogen‐doped carbon nanotubes (NCNTs) are usually selective and robust electrocatalysts for CO2 reduction to CO in aqueous media. However, the electronic property of NCNTs is strongly dependent on their curvature, the change of curvature has a great ...
Kuilin Lv   +4 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Green governance and its peer effect in the Yangtze River Delta region of China

open access: yesCarbon Neutralization, 2022
The extensive development of social economy and other fields poses challenges to environmental management in the new era. The pressure of climate adaptation and the failure of environmental regulation policies make the Chinese government seek a new ...
Hongda Liu
doaj   +1 more source

Neutralization against Omicron SARS-CoV-2 from previous non-Omicron infection

open access: yesbioRxiv, 2021
The spread of the Omicron SARS-CoV-2 variant underscores the importance of analyzing the cross-protection from previous non-Omicron infection. We have developed a high-throughput neutralization assay for Omicron SARS-CoV-2 by engineering the Omicron ...
Jing Zou   +7 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Insights into the synergistic effect between nickel and molybdenum for catalyzing urea electrooxidation

open access: yesCarbon Neutralization, 2022
The efficiency of many clean technologies, such as urea fuel cells, hydrogen production from urea‐containing water splitting, and sewage treatment, and so forth, is restricted due to the sluggish kinetics of the urea oxygen reaction (UOR).
Jiaqi Wang   +7 more
doaj   +1 more source

Enhanced SARS-CoV-2 neutralization by dimeric IgA

open access: yesScience Translational Medicine, 2020
Human dimeric IgA antibodies are potent neutralizers of SARS-CoV-2. Two is better than one for COVID-19 Most individuals that become infected with SARS-CoV-2, the virus that causes COVID-19, produce neutralizing antibodies against the virus. However, the
Zijun Wang   +19 more
semanticscholar   +1 more source

Neutralization of SARS-CoV-2 variants by convalescent and BNT162b2 vaccinated serum

open access: yesNature Communications, 2021
SARS-CoV-2 and its variants continue to infect hundreds of thousands every day despite the rollout of effective vaccines. Therefore, it is essential to understand the levels of protection that these vaccines provide in the face of emerging variants. Here,
T. Bates   +18 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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