Results 151 to 160 of about 304,289 (334)

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha   +4 more
wiley   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu   +8 more
wiley   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

open access: yesAdvanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns   +10 more
wiley   +1 more source

Age-specific kinetics of neutralizing antibodies and infection enhancement among ≤1 year-old Indian infants

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundInfants born to dengue-immune mothers acquire maternal antibodies to dengue. Maternal antibodies decline over time, making infants susceptible to primary dengue infections. Another important concern is the role of maternal antibodies in causing
Shweta Chelluboina   +3 more
doaj   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li   +8 more
wiley   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

open access: yesAdvanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh   +5 more
wiley   +1 more source

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