Highly Selective Exogenous Neutrophils Effectively Inhibit Growth of Colon Cancer under the Guidance of Precision Navigation [PDF]
ResearchThe diversity of neutrophils’ subtypes and functions in the tumor microenvironmentunderlies their contributions to both pro- and anti-tumorigenic activities.
Yunxi Yang +7 more
doaj +2 more sources
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
Clinical and Translational Medicine, 2023 Sepsis is a persistent systemic inflammatory condition involving multiple organ failures resulting from a dysregulated immune response to infection, and one of the hallmarks of sepsis is endothelial dysfunction.
Hao Zhang +6 more
semanticscholar +1 more source
Effect of Lonomia obliqua Venom on Human Neutrophils
Toxins, 2021 The significant incidence of deforestation in South America culminates in the contact of humans with typical forests species. Among these species, one may highlight Lonomia obliqua caterpillar, which, when touched by humans, can poison them through their
João Alfredo Moraes +8 more
doaj +1 more source
Dysregulated Neutrophil Phenotype and Function in Hospitalised Non-ICU COVID-19 Pneumonia
Cells, 2022 Rationale: Infection with the SARS-CoV2 virus is associated with elevated neutrophil counts. Evidence of neutrophil dysfunction in COVID-19 is based on transcriptomics or single functional assays. Cell functions are interwoven pathways, and understanding
Kylie B. R. Belchamber +13 more
doaj +1 more source
Neutrophil Activated by the Famous and Potent PMA (Phorbol Myristate Acetate)
Cells, 2022 This review will briefly outline the major signaling pathways in PMA-activated neutrophils. PMA is widely used to understand neutrophil pathways and formation of NETs.
Hylane Luiz Damascena +3 more
doaj +1 more source
Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases
Nature reviews. Immunology, 2022 Systemic autoimmune diseases are characterized by the failure of the immune system to differentiate self from non-self. These conditions are associated with significant morbidity and mortality, and they can affect many organs and systems, having ...
G. Wigerblad, M. Kaplan
semanticscholar +1 more source
Biomolecules, 2022 Bilirubin (BR) is a tetrapyrrolic compound stemming from heme catabolism with diverse physiological functions. It can be oxidized by H2O2 to form several degradation products, some of which have been detected in vivo and may contribute to the ...
Fei-Fei Yu +9 more
doaj +1 more source
Neutrophil phenotypes and functions in cancer: A consensus statement
Journal of Experimental Medicine, 2022 There is a growing appreciation for the vastness of neutrophil functional states in cancer. Quail et al. provide a consensus statement on mechanisms governing neutrophil heterogeneity in the context of malignancy and discuss controversies and solutions ...
D. Quail +24 more
semanticscholar +1 more source
Glutathione peroxidase 4 regulated neutrophil ferroptosis induces systemic autoimmunity
Nature Immunology, 2021 The linkage between neutrophil death and the development of autoimmunity has not been thoroughly explored. Here, we show that neutrophils from either lupus-prone mice or patients with systemic lupus erythematosus (SLE) undergo ferroptosis ...
Pengchong Li +10 more
semanticscholar +1 more source
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +13 more sources