Results 31 to 40 of about 749,501 (334)
Cell Cycle, 2015 Neutrophils are short-lived effector cells of the innate immune system that form the first line of defense against microbial pathogens.1 Recent studies show that, by migrating to bone marrow, these cells can also induce (VACV)-specific T cell responses.2 Neutrophils polarize to distinct phenotypes in response to environmental cytokine/chemokine signals.
Mariano Esteban, Mauro Di Pilato
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Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]
, 2018 Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J +7 more
core +1 more source
ERJ Open Research, 2015 In the airways of severe asthmatics, an increase of neutrophils and eosinophils is often observed despite high-dose corticosteroid therapy. We previously reported that interleukin-8-stimulated neutrophils induced trans-basement membrane migration (TBM ...
Fuyumi Nishihara +7 more
doaj +1 more source
Frontiers in Medicine, 2022 Transfusion of granulocyte concentrates (GC) is an alternative therapy for neutropenic patients with life-threatening infections. While neutrophils are the main source of antimicrobial activity, only neutrophil numbers are used to certify GCs.
Andréa Murru +19 more
doaj +1 more source
Circulation Research, 2015 More than a century ago, in 1881, Bizzozero1 discovered platelets and their role in primary hemostasis. Since this founding study, it has been shown that, in addition to the scaffold of platelets and fibrin, other proteins and cells play an important role in thrombus formation and stabilization.
Benoît Ho-Tin-Noé +1 more
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Single cell analysis of neutrophils NETs by Microscopic LSPR imaging system [PDF]
, 2019 A simple microengraving cell monitoring method for neutrophil extracellular traps (NETs) released from single neutrophils has been realized using a polydimethylsiloxane (PDMS) microwell array (MWA) sheet on a plasmon chip platform. An imbalance between
Espulgar, Wilfred +7 more
core +1 more source
Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]
, 2009 Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina +7 more
core +1 more source
Journal of Immunology Research, 2021 Neutrophils are prominent components of gastric cancer (GC) tumors and exhibit distinct phenotypes in GC environment. However, the phenotype, regulation, and clinical relevance of neutrophils in human GC are presently unknown. Here, immunohistochemistry,
Zhi-guo Shan +8 more
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Immunological Reviews, 2023 neutrofili, infiammazione, immunità
Marco A. Cassatella, William M. Nauseef
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Immunoreceptors on neutrophils
Seminars in Immunology, 2016 Neutrophils play a critical role in the host defense against infection, and they are able to perform a variety of effector mechanisms for this purpose. However, there are also a number of pathological conditions, including autoimmunity and cancer, in which the activities of neutrophils can be harmful to the host. Thus the activities of neutrophils need
van Rees, Dieke J +4 more
openaire +4 more sources