Results 121 to 130 of about 922,079 (252)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Incite 2012: Angels and Demons, March 10-12, 2012 [PDF]
, 2012 This is the concert program of the Incite 2012: Angels and Demons performance on Saturday, March 10, 2012 at 8:00 p.m., at the BMCC Tribeca Performing Arts Center, 199 Chambers St, New York. New York.
School of Music, Boston University
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Quality in SportThis study takes the humanities exchange of sports events as the research object, uses the literature method, the historical method and the logical analysis method to deeply interpret the essence of the humanities exchange of sports events in China and ...
Jin Huang, Shaojie Wang, Bo Jiang
doaj +1 more source
, 2009 This special section on ‘Rethinking Leninism’ emerges from sessions organized at the Society for Socialist Studies’ Annual Meetings, held at the Congress of the Humanities and Social Sciences in May 2009 at Carleton University in Ottawa, Ontario, Canada.
Levant, Alex
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Construction of home by Polish and Lithuanian migrants in the UK [PDF]
, 2006 Researchers across the social sciences and humanities have sought to understand the nature of people's affiliation with a particular place, to understand the emotional and symbolic ties that bind people to a place and make them feel at home.
Parutis, V.
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Construction of the Medical and Health Humanities System in China
Yixue yu zhexueDuring the advancement of the Healthy China initiative, facing the needs of social development and public health in the new era, the construction of a medical and health humanities system has become increasingly important and urgent.
Zhiguang DUAN, Chen WANG, Yan SHI
doaj +1 more source
Digital Humanities in the Classroom and Beyond: 1) How Scaffolding Saved the Day -- Integrating Omeka into Classroom Curricula 2) New Ecologies of Collaboration -- Digital Humanities and Renaissance Drama [PDF]
, 2018 This session will feature perspectives on digital humanities from presenters at two different institutions: 1) How Scaffolding Saved the Day: Integrating Omeka into Classroom Curricula This presentation chronicles a university’s journey to bring digital ...
Eastman, Teagan +2 more
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