Results 121 to 130 of about 922,978 (253)

Digital Humanities and MU's CI plan : draft document [PDF]

open access: yes, 2015
Key Planning Assumption: This cyberinfrastructure plan recognizes the leadership role of MU's Digital Humanities Commons and assumes achieving the objectives described by the DHC will address the priority needs of MU's current and emerging digital ...

core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Embedding the Library into Scientific and Scholarly Communication through Knowledge Management [PDF]

open access: yes, 1992
Knowledge management is a new role for academic research libraries that has the potential to integrate the library into scholarly and scientific communication in a significant way.
Lucier, Richard E.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Shape the international discourse of Humanities Exchange in China's sports events within The Belt and Road Initiative

open access: yesQuality in Sport
This study takes the humanities exchange of sports events as the research object, uses the literature method, the historical method and the logical analysis method to deeply interpret the essence of the humanities exchange of sports events in China and ...
Jin Huang, Shaojie Wang, Bo Jiang
doaj   +1 more source

Construction of home by Polish and Lithuanian migrants in the UK [PDF]

open access: yes, 2006
Researchers across the social sciences and humanities have sought to understand the nature of people's affiliation with a particular place, to understand the emotional and symbolic ties that bind people to a place and make them feel at home.
Parutis, V.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Construction of the Medical and Health Humanities System in China

open access: yesYixue yu zhexue
During the advancement of the Healthy China initiative, facing the needs of social development and public health in the new era, the construction of a medical and health humanities system has become increasingly important and urgent.
Zhiguang DUAN, Chen WANG, Yan SHI
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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