Results 81 to 90 of about 922,079 (252)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Coming Up Taller [PDF]

open access: yes, 2010
Coming Up Taller is a report filled with hope, a narrative about youth learning to paint, sing, write plays and poems, take photographs, make videos and play drums or violins.

core  

Research \u2018Values\u2019 in the Humanities: Funding Policies, Evaluation and Cultural Resources. Some Introductory Remarks [PDF]

open access: yes, 2015
: In her capacity as guest editor, the author introduces a set of essays examining the trends, risks, needs, pressures, and prospects of the humanities after recent reforms to tertiary education throughout Europe. By focusing on the educational, cultural,
Ferrini, Cinzia
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Visiting Professorship in Undergraduate Medical Education at the University of Alberta: Reflections on possibilities for medical humanities in China, and elsewhere

open access: yesMedEdPublish, 2020
Enhancing humanities in medical education is a pressing concern in China. Similar to other countries, medical education in China evolved over the past century to emphasize bioscience and technology in treating illness and disease.
Liying Wei   +3 more
doaj  

Przyczynek do rozważań nad przynależnością dziedzinową nauk o polityce

open access: yesPoliteja, 2015
Since the number of academic specializations and disciplines has consistently been increasing, it has become necessary to supplement present classifications and categorizations, as well as come up with new ones, on a regular basis.
Tadeusz Wallas
doaj   +1 more source

Learning from Jesus’ Wife: What Does Forgery Have to Do with the Digital Humanities? [PDF]

open access: yes, 2019
McGrath’s chapter on the so-called Gospel of Jesus’ Wife sets aside as settled the question of the papyrus’ authenticity, and explores instead what we can learn about the Digital Humanities and scholarly interaction in a digital era from the way the ...
McGrath, James F
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Faculty recital: Sarah Arneson with George Kern, January 27, 2004 [PDF]

open access: yes, 2004
This is the concert program of the faculty recital of Sarah Arneson and George Kern on Tuesday, January 27, 2004 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts. Works performed were Misera, dove son? K.
School of Music, Boston University
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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