Results 91 to 100 of about 599,978 (240)

Expression of Ig receptors on the U937-NF-κB reporter cell line.

open access: yes, 2016
U937 cells express FcγRI, FcγRII, FcαRI of Fc receptors (A). Transfection with NF-κB-GFP did not alter the Fc receptor expression patterns in the U937 cell line (B).
László Homolya (538824)   +8 more
core   +1 more source

Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode

open access: yesCancer Biology & Medicine, 2017
The role of the transcription factor NF-κB in shaping the cancer microenvironment is becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF-κB function, and causes extensive changes in genomic chromatin that ultimately ...
Spiros A. Vlahopoulos
doaj   +1 more source

CIT increased NF-κB activation in aorta.

open access: yes, 2015
(A) Expression of NF-κB p65, phospho-NF-κB p65, I-κB, and phospho-I-κB in aorta analyzed by Western blotting. (B) The levels of phospho-NF-κB p65/NF-κB p65 and phospho-I-κB/I-κB. Data are presented as mean ± SEM (n = 5).
Jian-Bao Liu (733546)   +7 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

NF-κB translocation assay ImageJ macro

open access: yes, 2019
This is ImageJ macro used to determine the degree of NF-κB translocation in cells stained for NF-κB and nuclear signal. It is a part of publication entitled "Plasma extracellular vesicles signal spleen fibroblasts facilitating Plasmodium vivax adherence".
Chojnacki, Jakub (8330793)   +1 more
core   +1 more source

NF-κB mediated the effect of GDNF on CXCL1 and proliferation in rat C6 glioma cells.

open access: yes, 2023
(A) Western blot showed that NF-κB mediated the effect of exogenous GDNF on CXCL1. (B) The statistical results of (A). (C) NF-κB mediated GDNF enhanced the activity of CXCL1 gene promoter region by double luciferase reporter gene activity.
Dian Shuai Gao (16851471)   +5 more
core   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang   +16 more
wiley   +1 more source

Plumbagin Suppresses the Invasion of HER2-Overexpressing Breast Cancer Cells through Inhibition of IKKα-Mediated NF-κB Activation.

open access: yesPLoS ONE, 2016
HER2-overexpressing breast cancers account for about 30% of breast cancer occurrences and have been correlated with increased tumor aggressiveness and invasiveness.
Anna Kawiak, Anna Domachowska
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park   +5 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez   +12 more
wiley   +1 more source

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