Results 11 to 20 of about 396,196 (289)
Nuclear factor-kappa B inhibition can enhance apoptosis of differentiated thyroid cancer cells induced by 131I. [PDF]
PLoS ONE, 2012 OBJECTIVE: To evaluate changes of nuclear factor-kappa B (NF-κB) during radioiodine 131 ((131)I) therapy and whether NF-κB inhibition could enhance (131)I-induced apoptosis in differentiated thyroid cancer (DTC) cells in a synergistic manner.
Zhaowei Meng +5 more
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Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer
Biomolecules, 2020 The nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor central to inflammation and various malignant diseases in humans. The regulation of NF-κB can be influenced by a myriad of post-translational modifications (PTMs), including ...
Aishat Motolani +3 more
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Understanding NF‐κB signaling via mathematical modeling
Molecular Systems Biology, 2008 Mammalian inflammatory signaling, for which NF‐κB is a principal transcription factor, is an exquisite example of how cellular signaling pathways can be regulated to produce different yet specific responses to different inflammatory insults. Mathematical
Raymond Cheong +2 more
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Kaohsiung Journal of Medical Sciences, 2012 Modulation of nuclear factor-kappa B (NF-κB) expression has important clinical implications including anti-inflammation. Recently, we have shown that direct regulation of NF-κB/p65 subunit may account for tacrolimus ointment’s remarkable clinical ...
Ching-Shuang Wu +5 more
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Listeria monocytogenesinfection of Caco-2 human epithelial cells induces activation of transcription factor NF-κB/Rel-like DNA binding activities [PDF]
FEMS Microbiology Letters, 1999 The effect of Listeria monocytogenes infection on the cellular level of transcription factor NF-kappa B in the human epithelia-like cell line Caco-2 was investigated. Infection with L. monocytogenes or treatment with lipoteichoic acid induced the formation of three NF-kappa B-like DNA-protein complexes C1, C2, and C3, which were identified as ...
N, Hauf, W, Goebel, F, Fiedler, M, Kuhn
openaire +2 more sources
Translational Psychiatry, 2021 Bipolar disorder and schizophrenia have multiple clinical and genetic features in common, including shared risk associated with overlapping susceptibility loci in immune-related genes. Higher activity of the nuclear factor-κB (NF-κB) transcription factor
Kaitlyn M. Roman +3 more
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Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation [PDF]
Frontiers in Genetics, 2014 Cardiovascular diseases such as atherosclerosis are one of the leading causes of morbidity and mortality worldwide. The clinical manifestations of atherosclerosis, which include heart attack and stroke, occur several decades after initiation of the disease and become more severe with age.
Cheng, Henry S. +4 more
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NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
Frontiers in Oncology, 2023 IntroductionImproving treatments for Diffuse Large B-Cell Lymphoma (DLBCL) is challenged by the vast heterogeneity of the disease. Nuclear factor-κB (NF-κB) is frequently aberrantly activated in DLBCL. Transcriptionally active NF-κB is a dimer containing
Eleanor Jayawant +8 more
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The Regulation of NF-κB Subunits by Phosphorylation
Cells, 2016 The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of genes that control inflammation, immune cell development, cell cycle ...
Frank Christian +2 more
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A role for NF-κB activity in skin hyperplasia and the development of keratoacanthomata in mice. [PDF]
PLoS ONE, 2013 Previous studies have implicated NF-κB signaling in both cutaneous development and oncogenesis. However, these studies have been limited in part by the lethality that results from extreme over- or under-expression of NF-κB in available mouse models. Even
Brian Poligone +5 more
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