Results 21 to 30 of about 599,978 (240)

Tiliroside Produced Anti-Neuroinflammatory Effects Through Interference With NF-κB And MAPK Signalling In LPS+ IFN-γ Stimulated BV-2 Microglia. [PDF]

, 2014
Tiliroside is a glycosidic flavonoid, which possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities. It is contained in several dietary plants like linden, rosehip, raspberry and strawberry [1, 2].
Aderogba, Mutallib A., Olajide, Olumayokun A, Velagapudi, Ravikanth   +2 more
core   +2 more sources

The Regulation of NF-κB Subunits by Phosphorylation

Cells, 2016
The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of genes that control inflammation, immune cell development, cell cycle ...
Frank Christian, Emma L. Smith, Ruaidhrí J. Carmody   +2 more
doaj   +1 more source

A role for NF-κB activity in skin hyperplasia and the development of keratoacanthomata in mice. [PDF]

PLoS ONE, 2013
Previous studies have implicated NF-κB signaling in both cutaneous development and oncogenesis. However, these studies have been limited in part by the lethality that results from extreme over- or under-expression of NF-κB in available mouse models. Even
Brian Poligone, Matthew S Hayden, Luojing Chen, Alice P Pentland, Eijiro Jimi, Sankar Ghosh   +5 more
doaj   +1 more source

Additional file 4 of Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblasts

, 2022
Additional file 4. The raw data of western blot of p-p65-NF-κB, p65-NF-κB, Cyclin D1 and GAPDH. After incubation with or without ARS-853, the amounts of (a) p-p65-NF-κB protein levels, (b) p65-NF-κB protein levels, (c) cyclin D1 protein levels and (d ...
Jinzhu Fan (12405409), Dingjun Hao (12199388), Shuguang Liu (12405412), Yunshan Guo (12405406)   +3 more
core   +1 more source

Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

Biomedicines
Backgroung/objectives: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of malignant lymphoma and is a heterogeneous disease with various gene and chromosomal abnormalities.
Aurélie Montagne, Konstantina Kotta, Karoline Kielbassa-Elkadi, Isabelle Martins, José Ángel Martinez-Climent, Guido Kroemer, Catherine Thieblemont, Véronique Baud   +7 more
doaj   +1 more source

The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability

Frontiers in Immunology, 2019
Regulatory T cells (Tregs) play a major role in immune homeostasis and in the prevention of autoimmune diseases. It has been shown that c-Rel is critical in Treg thymic differentiation, but little is known on the role of NF-κB on mature Treg biology.
Emilie Ronin, Martina Lubrano di Ricco, Romain Vallion, Jordane Divoux, Ho-Keun Kwon, Sylvie Grégoire, Davi Collares, Angéline Rouers, Véronique Baud, Christophe Benoist, Benoit L. Salomon   +10 more
doaj   +1 more source

The Role of Ubiquitination in NF-κB Signaling during Virus Infection

Viruses, 2021
The nuclear factor κB (NF-κB) family are the master transcription factors that control cell proliferation, apoptosis, the expression of interferons and proinflammatory factors, and viral infection. During viral infection, host innate immune system senses
Kun Song, Shitao Li
doaj   +1 more source

Natural Small Molecules Targeting NF-κB Signaling in Glioblastoma [PDF]

, 2021
Nuclear factor-κB (NF-κB) is a transcription factor that regulates various genes that mediate various cellular activities, including propagation, differentiation, motility, and survival.
Albadrani, Ghadeer M, Bin Emran, Talha, Abdullah Al Mamun, Alanazi, Ibtesam S, Ghadeer M. Albadrani, Ibtesam S. Alanazi, Nasrin, Fatema, Talha Bin Emran, Kabir, Md Tanvir, Amany A. Sayed, Rauf, Abdur, Al Mamun, Abdullah, Mousa, Shaker A, Shaker A. Mousa, Fatema Nasrin, Sarwar, Md Shahid, Abdur Rauf, Md. Sahab Uddin, Mohamed M. Abdel-Daim, Md. Tanvir Kabir, Sayed, Amany A, Md. Shahid Sarwar, Uddin, Md Sahab, Abdel-Daim, Mohamed M   +23 more
core   +1 more source

Additional file 3 of Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblasts

, 2022
Additional file 3. The raw data of western blot of Ras-GRF, Ras, p-p65-NF-κB, p65-NF-κB and GAPDH. a Ras-GRF protein levels, (b) Ras protein levels, (c) p-p65-NF-κB protein levels, (d) p65-NF-κB protein levels (e) GAPDH protein levels were examined by ...
Jinzhu Fan (12405409), Dingjun Hao (12199388), Shuguang Liu (12405412), Yunshan Guo (12405406)   +3 more
core   +1 more source

Nuclear Factor-κB/p65 (Rel A) Is Constitutively Activated in Human Prostate Adenocarcinoma and Correlates with Disease Progression

Neoplasia: An International Journal for Oncology Research, 2004
Aberrant nuclear factor-κB (NF-κB) activation has been implicated in the pathogenesis of several human malignancies. In this study, we determined whether NF-κB is constitutively activated in human prostate adenocarcinoma, and, if so, whether increased NF-
Sanjeev Shukla, Gregory T. MacLennan, Pingfu Fu, Jigar Patel, Susan R. Marengo, Martin l. Resnick, Sanjay Gupta   +6 more
doaj   +1 more source