Results 41 to 50 of about 577,005 (273)

The Role of Ubiquitination in NF-κB Signaling during Virus Infection

Viruses, 2021
The nuclear factor κB (NF-κB) family are the master transcription factors that control cell proliferation, apoptosis, the expression of interferons and proinflammatory factors, and viral infection. During viral infection, host innate immune system senses
Kun Song, Shitao Li
doaj   +1 more source

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes [PDF]

, 2011
NF-κB is involved in immune responses, inflammation, oncogenesis, cell proliferation and apoptosis. Even though NF-κB can be activated by DNA damage via Ataxia telangiectasia-mutated (ATM) signalling, little was known about an involvement in DNA repair ...
Salles, Daniela, Bernd Baumann, Lisa Wiesmüller, Volcic, Meta, Fulda, Simone, Meta Volcic, Volcic, M., Wiesmueller, L., Baumann, B., Daniel, P., Sabine Karl, Simone Fulda, Daniela Salles, Peter Daniel, Karl, Sabine, Baumann, Bernd, Fulda, S., Salles, D., Karl, S., Daniel, Peter, Wiesmüller, Lisa   +20 more
core   +1 more source

WITHDRAWN: Inhibition of CHOP weakens the promotion of chronic intermittent hypoxia on epithelial cells apoptosis via inhibiting PI3K-Akt and NF-κB signaling pathways

Oncotarget, 2017
// Yi-Bin Wang 1, * , Yin Ni 2, * , Ren-Hua Sun 2 , Xiao-Zhou Mou 3 , Fang Han 2 , Qian Li 2 , Hai-Jun Huang 4 , Jing-Quan Liu 2 and Yue-Xing Tu 2 1 Department of Cardiology, Chun’an First People’s Hospital, Zhejiang Provincial People’s Hospital Chun’an Branch, Hangzhou, Zhejiang 311700, China 2 Department of Critical Care Medicine ...
Yi-Bin Wang, Yi-Bin Wang, Yin Ni, Yin Ni, Ren-Hua Sun, Ren-Hua Sun, Xiao-Zhou Mou, Xiao-Zhou Mou, Fang Han, Fang Han, Qian Li, Qian Li, Hai-Jun Huang, Hai-Jun Huang, Jing-Quan Liu, Jing-Quan Liu, Yue-Xing Tu, Yue-Xing Tu   +17 more
openaire   +1 more source

Listeria monocytogenesinfection of Caco-2 human epithelial cells induces activation of transcription factor NF-κB/Rel-like DNA binding activities [PDF]

FEMS Microbiology Letters, 1999
The effect of Listeria monocytogenes infection on the cellular level of transcription factor NF-kappa B in the human epithelia-like cell line Caco-2 was investigated. Infection with L. monocytogenes or treatment with lipoteichoic acid induced the formation of three NF-kappa B-like DNA-protein complexes C1, C2, and C3, which were identified as ...
N, Hauf, W, Goebel, F, Fiedler, M, Kuhn
openaire   +2 more sources

Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

Biomedicines
Backgroung/objectives: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of malignant lymphoma and is a heterogeneous disease with various gene and chromosomal abnormalities.
Aurélie Montagne, Konstantina Kotta, Karoline Kielbassa-Elkadi, Isabelle Martins, José Ángel Martinez-Climent, Guido Kroemer, Catherine Thieblemont, Véronique Baud   +7 more
doaj   +1 more source

Model simplification of signal transduction pathway networks via a hybrid inference strategy [PDF]

, 2008
A full-scale mathematical model of cellular networks normally involves a large number of variables and parameters. How to effectively develop manageable and reliable models is crucial for effective computation, analysis and design of such systems.
Yue, Hong, Jia, Jianfang
core   +4 more sources

Nuclear Factor-κB/p65 (Rel A) Is Constitutively Activated in Human Prostate Adenocarcinoma and Correlates with Disease Progression

Neoplasia: An International Journal for Oncology Research, 2004
Aberrant nuclear factor-κB (NF-κB) activation has been implicated in the pathogenesis of several human malignancies. In this study, we determined whether NF-κB is constitutively activated in human prostate adenocarcinoma, and, if so, whether increased NF-
Sanjeev Shukla, Gregory T. MacLennan, Pingfu Fu, Jigar Patel, Susan R. Marengo, Martin l. Resnick, Sanjay Gupta   +6 more
doaj   +1 more source

Kombinasi Artemisinin dan Ekstrak Moringa oleifera Menurunkan Ekspresi NF-κB namun Tidak Menurunkan Ekspresi iNOS pada Otak Mencit Diinfeksi Malaria

Jurnal Kedokteran Brawijaya, 2015
Malaria otak merupakan manifestasi tersering dari infeksi malaria berat yang ditandai dengan respon inflamasi berlebih di otak. Untuk mencegah terjadinya resistensi, penggunaan obat antimalaria standar (artemisinin) harus dikombinasikan dengan obat antimalaria lain.
Herpan Syafii Harahap, Mochammad Dalhar, Tinny Endang Endang H, Eviana Norahmawati, Loeki Enggar Fitri   +4 more
openaire   +2 more sources

The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability

Frontiers in Immunology, 2019
Regulatory T cells (Tregs) play a major role in immune homeostasis and in the prevention of autoimmune diseases. It has been shown that c-Rel is critical in Treg thymic differentiation, but little is known on the role of NF-κB on mature Treg biology.
Emilie Ronin, Martina Lubrano di Ricco, Romain Vallion, Jordane Divoux, Ho-Keun Kwon, Sylvie Grégoire, Davi Collares, Angéline Rouers, Véronique Baud, Christophe Benoist, Benoit L. Salomon   +10 more
doaj   +1 more source

Ginkgetin inhibits proliferation of HeLa cells via activation of p38/NF-κB pathway

Cellular and Molecular Biology, 2019
Effect of ginkgetin on proliferation of human cervical cancer (HeLa) cells and the underlying mechanism   were investigated. Human cervical cancer (HeLa) cells were cultured at 37 °C in 10 % fetal bovine serum (FBS) supplemented RPMI 1640 medium in a humidified incubator containing 5 % CO2.
Jianxia, Cheng, Yun, Li, Jianping, Kong
openaire   +3 more sources