Results 51 to 60 of about 525,635 (287)

MOESM1 of Amentoflavone ameliorates cold stress-induced inflammation in lung by suppression of C3/BCR/NF-κB pathways

open access: yes, 2019
Additional file 1. Assessment of inflammation due to cold stress.
Cai, Jiayi   +4 more
openaire   +1 more source

NF-κB total and phosphorylated in sham and infarcted rats with and without açai supplementation. [PDF]

open access: yes, 2022
(A) NF-κB total: nuclear factor kappa B, (B) pNF-κB: nuclear factor kappa B: phosphorylated nuclear factor kappa B. Sample size: SA0 = 8; SA2 = 8; SA5 = 6; IA0 = 6; IA2 = 6; IA5 = 7. (TIF)
Ana Carolina Cardoso (12197285)   +15 more
core   +1 more source

The levels of NF-κB p50 and NF-κB p65 play a role in thyroid carcinoma malignancy in vivo

open access: yesJournal of International Medical Research, 2018
Background To investigate the relationship between the levels of nuclear factor (NF)-κB p50 and NF-κB p65 and tumour characteristics in patients with thyroid carcinoma.
Fei Le   +4 more
doaj   +1 more source

Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain

open access: yesJournal of Neuroinflammation, 2019
Background While NF-κB p50 function is impaired in central nervous system disease, aging in non-CNS tissues, and response to reactive oxygen species, the role of NF-κB p50 in aging-associated microglial pro-inflammatory priming is poorly understood ...
Thomas Taetzsch   +4 more
doaj   +1 more source

Gentiopicrin exerts anti-rheumatic effect in human fibroblast-like synoviocytes via inhibition of p38MAPK/NF-κB pathway

open access: yesCellular and Molecular Biology, 2019
To investigate the effect of gentiopicrin on the expressions of inflammatory factors in human fibroblast-like synoviocytes (HFLS) and the underlying mechanism. Human fibroblast-like synoviocytes (HFLS) were cultured in vitro at 37 °C in Dulbecco's modified Eagle's medium (DMEM) supplemented with 5 % fetal bovine serum (FBS) in a humidified incubator ...
Nian, Zhang   +4 more
openaire   +3 more sources

Dexamethasone suppresses interleukin-1β-induced human β-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-κB transcriptional factor in A549 cells [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 2007
Human beta-defensin (HBD)-2 is an inducible antimicrobial peptide that plays an important role in innate immunity. Glucocorticoids, on the other hand, exert immunosuppressive and anti-inflammatory actions. We have previously reported that interleukin (IL)-1beta induces HBD-2 mRNA expression through the activation of nuclear factor-kappaB (NF-kappaB ...
Byeong-Churl Jang   +4 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Neutrophil Gelatinase-associated lipocalin (NGAL), a NF-kB regulated gene, is a survival factor for thyroid neoplastic cells [PDF]

open access: yes, 2008
NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell line, FRO, leads to an increased susceptibility to ...
Iannetti, Alessio
core  

Risk stratification of patients with diffuse large B-cell lymphoma using plasma NMR-based metabolomics at diagnosis

open access: yesBlood Advances
: Early detection of ultrahigh-risk diffuse large B-cell lymphoma (DLBCL) is an unmet medical need to aid patient stratification for alternative treatment approaches.
Aurélie Montagne   +18 more
doaj   +1 more source

The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability

open access: yesFrontiers in Immunology, 2019
Regulatory T cells (Tregs) play a major role in immune homeostasis and in the prevention of autoimmune diseases. It has been shown that c-Rel is critical in Treg thymic differentiation, but little is known on the role of NF-κB on mature Treg biology.
Emilie Ronin   +10 more
doaj   +1 more source

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