Results 11 to 20 of about 495,858 (236)

Bridelia ferruginea Produces Anti-neuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling [PDF]

, 2012
Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models.
Aderogba, Mutallib A., Fiebich, Bernd L., Aderogba, Mutalib A., Okorji, Uchechukwu P., Okorji, U. P., Fiebich, B.L., Olajide, Olumayokun A.   +6 more
core   +1 more source

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes [PDF]

, 2011
NF-κB is involved in immune responses, inflammation, oncogenesis, cell proliferation and apoptosis. Even though NF-κB can be activated by DNA damage via Ataxia telangiectasia-mutated (ATM) signalling, little was known about an involvement in DNA repair ...
Salles, Daniela, Bernd Baumann, Lisa Wiesmüller, Volcic, Meta, Fulda, Simone, Meta Volcic, Volcic, M., Wiesmueller, L., Baumann, B., Daniel, P., Sabine Karl, Simone Fulda, Daniela Salles, Peter Daniel, Karl, Sabine, Baumann, Bernd, Fulda, S., Salles, D., Karl, S., Daniel, Peter, Wiesmüller, Lisa   +20 more
core   +1 more source

Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression [PDF]

Nature Communications, 2018
AbstractKnowledge of stromal factors that have a role in the transcriptional regulation of metabolic pathways aside from c-Myc is fundamental to improvements in lymphoma therapy. Using a MYC-inducible human B-cell line, we observed the cooperative activation of STAT3 and NF-κB by IL10 and CpG stimulation.
Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja, Gronwald, Wolfram, Reinders, Jörg, Engelmann, Julia C., Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J., Kube, D.   +18 more
openaire   +5 more sources

WITHDRAWN: Inhibition of CHOP weakens the promotion of chronic intermittent hypoxia on epithelial cells apoptosis via inhibiting PI3K-Akt and NF-κB signaling pathways

Oncotarget, 2017
// Yi-Bin Wang 1, * , Yin Ni 2, * , Ren-Hua Sun 2 , Xiao-Zhou Mou 3 , Fang Han 2 , Qian Li 2 , Hai-Jun Huang 4 , Jing-Quan Liu 2 and Yue-Xing Tu 2 1 Department of Cardiology, Chun’an First People’s Hospital, Zhejiang Provincial People’s Hospital Chun’an Branch, Hangzhou, Zhejiang 311700, China 2 Department of Critical Care Medicine ...
Yi-Bin Wang, Yi-Bin Wang, Yin Ni, Yin Ni, Ren-Hua Sun, Ren-Hua Sun, Xiao-Zhou Mou, Xiao-Zhou Mou, Fang Han, Fang Han, Qian Li, Qian Li, Hai-Jun Huang, Hai-Jun Huang, Jing-Quan Liu, Jing-Quan Liu, Yue-Xing Tu, Yue-Xing Tu   +17 more
openaire   +1 more source

Listeria monocytogenesinfection of Caco-2 human epithelial cells induces activation of transcription factor NF-κB/Rel-like DNA binding activities [PDF]

FEMS Microbiology Letters, 1999
The effect of Listeria monocytogenes infection on the cellular level of transcription factor NF-kappa B in the human epithelia-like cell line Caco-2 was investigated. Infection with L. monocytogenes or treatment with lipoteichoic acid induced the formation of three NF-kappa B-like DNA-protein complexes C1, C2, and C3, which were identified as ...
N, Hauf, W, Goebel, F, Fiedler, M, Kuhn
openaire   +2 more sources

Effect of Aqueous Ozone on the NF-κB System [PDF]

, 2007
Ozone has been proposed as an alternative oral antiseptic in dentistry, due to its antimicrobial power reported for gaseous and aqueous forms, the latter showing a high biocompatibility with mammalian cells.
Paschos, E., Ern, K., Jakob, F.M., Hickel, R., Huth, K.C., Cappello, C., Quirling, M., Saugel, B., Brand, K.   +8 more
core   +1 more source

NF-κB affects E-box-mediated transcription.

, 2021
Steady-state luciferase reporter assay in transiently transfected 293T cells. (A) NF-κB itself, in the absence of BMAL1/CLOCK (B/C), did not activate the E-box transcription from the 3xE-box::Luc or Per2-dLuc reporters (left, middle), but repressed BMAL1/
Yang Shen (66591), Carrie L. Partch (1980499), David W. Hammers (3357035), Zhiguang Huo (785658), Wei Wang (17594), Andrew R. Morris (10090727), Lauren J. Francey (9270960), John B. Hogenesch (149244), Mehari Endale (11740641), Rachel L. Harold (11740644), Zhao-Hui Wu (8159670), Andrew C. Liu (11740647)   +11 more
core   +1 more source

An unexpected twist to the activation of IKKβ:TAK1 primes IKKβ for activation by autophosphorylation [PDF]

, 2014
IKKß {IkB [inhibitor of NF-?B (nuclear factor ?B)] kinase ß} is required to activate the transcription factor NF-?B, but how IKKß itself is activated in vivo is still unclear.
Lawrence, T., Peggie, M. W., Lawrence, Toby, Peggie, Mark W., Clark, Kristopher, Cohen, P., Cohen, Philip; id_orcid, Clark, K., Zhang, Jiazhen, Zhang, J.   +9 more
core   +1 more source

Ekspresi dan Aktivasi Sub Unit p65 NF-κB pada Sel Mononuklear Penderita Sindrom Nefrotik Resisten Steroid Anak

Jurnal Kedokteran Brawijaya, 2013
Resitance  to  steroid  therapy  is  a  poor  prognosis  sign  for  nephrotic  syndrome,  but  this  mechanism is  still unclear. NF-κB has been reported to affect the glucocorticoid at the T cell through the transrepression in  the glucocorticoid  receptor .  Until  know,  this  study  was  still  limited.  The  aim  of  
Brigitta Ida RV Corebima, Krisni Subandiyah, Loeki Enggar Fitri   +2 more
openaire   +2 more sources

Plant polyphenols as inhibitors of NF-κB induced cytokine production—a potential anti-inflammatory treatment for Alzheimer's disease? [PDF]

Frontiers in Molecular Neuroscience, 2015
Alzheimer’s disease (AD) is a neurodegenerative disorder that impacts the daily lives of many sufferers throughmemory loss as well as behavioral and cognitive changes. AD is themost common form of dementia. One in ten people over the age of 65, and around half of those over 85 have AD.
Karunaweera, Niloo (S31677), Raju, Ritesh (R17740), Gyengesi, Erika (R17270), Muench, Gerald (R12224)   +3 more
openaire   +3 more sources