Results 11 to 20 of about 548,906 (279)

TLR7, TLR9, MyD88, and NF-κB role on platelet aggregation in Yucatecan patients with type 2 diabetes

Alad, 2022
Objective: To analyze the expression of TLR7, TLR9, and signaling proteins MyD88 and NF-κB, and their relationship with platelet aggregation in Yucatecan patients with type 2 diabetes. Material and methods: Platelet aggregation was determined by light transmission and protein expression by flow cytometry in 31 patients and 29 controls from Yucatan ...
Lucía G. González-Espinosa, Irma G. Quintal-Ortiz, Yumi E. Nakazawa-Ueji, Juan D. Villarreal-Ku, Ligia G. Alonso-Salomón, Isaac A. López-Briceño, Nina Valadez-González, Guillermo Valencia-Pacheco   +7 more
openaire   +2 more sources

NF-κB signaling regulates myelination in the CNS [PDF]

Frontiers in Molecular Neuroscience, 2014
Besides myelination of neuronal axons by oligodendrocytes to facilitate propagation of action potentials, oligodendrocytes also support axon survival and function. A key transcription factor involved in these processes is nuclear factor-κB (NF-κB), a hetero or homodimer of the Rel family of proteins, including p65, c-Rel, RelB, p50, and p52.
Thomas eBlank, Marco ePrinz, Marco ePrinz   +2 more
openaire   +3 more sources

Oscillation dynamics underlie functional switching of NF-κB for B-cell activation. [PDF]

, 2016
Transcription factor nuclear factor kappa B (NF-κB) shows cooperative switch-like activation followed by prolonged oscillatory nuclear translocation in response to extracellular stimuli.
Aihara, Kazuyuki, Behar, Marcelo, Hoffmann, Alexander, Inoue, Kentaro, Okada-Hatakeyama, Mariko, Shinohara, Hisaaki, Tanaka, Gouhei, Yumoto, Noriko   +7 more
core   +1 more source

Parthenolide attenuates LPS-induced activation of NF-κB in a time-dependent manner in rat myocardium. [PDF]

, 2012
Parthenolide (PTN), a selective nuclear factor kappa B (NF-κB) inhibitor, has been used extensively to inhibit NF-κB activation. The duration of the inhibitory effect of PTN on NF-κB in vivo remains unclear.
Liu, Chunfeng, Liu, Hong, Liu, Xia, Qiao, Shigang, Wang, Chen, Wu, Xuemei, Xie, Hong   +6 more
core   +1 more source

Varied effects of algal symbionts on transcription factor NF-κB in a sea anemone and a coral: possible roles in symbiosis and thermotolerance [PDF]

, 2019
Many cnidarians, including the reef-building corals, undergo symbiotic mutualisms with photosynthetic dinoflagellate algae of the family Symbiodiniaceae.
Benson, Brooke E., Camacho, Dimitrios J., Cleves, Philip A., Davies, Sarah W., Gilmore, Thomas D., Hemond, Olivia, Kriefall, Nicola G., Mansfield, Katelyn M., Pedroza, Monique, Pringle, John R., Siggers, Trevor, Van Vlack, Emily   +11 more
core   +1 more source

Lipid peroxidation and apoptotic response in rat brain areas induced by long-term administration of nandrolone: the mutual crosstalk between ROS and NF-kB [PDF]

, 2016
The aim of this study was to evaluate the played by oxidative stress in the apoptotic response in different brain areas of rats chronically treated with supra-physiological doses of nandrolone decanoate (ND).
Busardo', FRANCESCO PAOLO, Cantatore, Santina, Cerretani, Daniela, Fineschi, Vittorio, Frati, Paola, Moltoni, Laura, Neri, Margherita, Pomara, Cristoforo, Riezzo, Irene, Turillazzi, Emanuela   +9 more
core   +2 more sources

CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter. [PDF]

, 2017
The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors controlling this complex response, but some aspects of its regulation remain unclear.
Carpenter, Susan, Covarrubias, Sergio, Fong, Nicholas, Hanley, Nicole, Katzman, Sol, McManus, Michael T, Robinson, Elektra K, Shapleigh, Barbara, Vollmers, Apple   +8 more
core   +1 more source

Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression [PDF]

Nature Communications, 2018
AbstractKnowledge of stromal factors that have a role in the transcriptional regulation of metabolic pathways aside from c-Myc is fundamental to improvements in lymphoma therapy. Using a MYC-inducible human B-cell line, we observed the cooperative activation of STAT3 and NF-κB by IL10 and CpG stimulation.
Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja, Gronwald, Wolfram, Reinders, Jörg, Engelmann, Julia C., Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J., Kube, D.   +18 more
openaire   +5 more sources

Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer

Biomolecules, 2020
The nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor central to inflammation and various malignant diseases in humans. The regulation of NF-κB can be influenced by a myriad of post-translational modifications (PTMs), including ...
Aishat Motolani, Matthew Martin, Mengyao Sun, Tao Lu   +3 more
doaj   +1 more source

Nuclear factor-kappa B inhibition can enhance apoptosis of differentiated thyroid cancer cells induced by 131I. [PDF]

PLoS ONE, 2012
OBJECTIVE: To evaluate changes of nuclear factor-kappa B (NF-κB) during radioiodine 131 ((131)I) therapy and whether NF-κB inhibition could enhance (131)I-induced apoptosis in differentiated thyroid cancer (DTC) cells in a synergistic manner.
Zhaowei Meng, Shanshan Lou, Jian Tan, Ke Xu, Qiang Jia, Wei Zheng   +5 more
doaj   +1 more source